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Reviews in Fluorescence 2005 pp 153–168Cite as

Time-Resolved Fluorescence in Biomedical Diagnostics

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Part of the book series: Reviews in Fluorescence ((RFLU,volume 2005))

Abstract

The application of time-resolving fluorescence techniques in biomedical research has been a challenge for many years. Since radiative and non-radiative transitions from the excited state of a molecule to its ground state are competing, the fluorescence lifetime (given as the reciprocal of the sum of all transition rates) of a molecule is sensitive to numerous parameters, e.g. its conformation or interaction with adjacent molecules. Therefore, fluorescence lifetime measurements can give numerous informations about the microenvironment of specific molecules

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Authors and Affiliations

  1. Institut für Angewandte Forschung, Beethovenstraße 1, 73430, Aalen, Germany

    Herbert Schneckenburger

  2. Institut für Angewandte Forschung, Hochschule Aalen, Beethovenstraße 1, 73430, Aalen, Germany

    Michael Wagner

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  1. Herbert Schneckenburger
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Editors and Affiliations

  1. Institute of Fluorescence and Center for Fluorescence Spectroscopy, University of Maryland Biotechnology Institute, Baltimore, Maryland

    Chris D. Geddes

  2. Center for Fluorescence Spectroscopy, University of Maryland School of Medicine, Baltimore, Maryland

    Joseph R. Lakowicz

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Schneckenburger, H., Wagner, M. (2005). Time-Resolved Fluorescence in Biomedical Diagnostics. In: Geddes, C.D., Lakowicz, J.R. (eds) Reviews in Fluorescence 2005. Reviews in Fluorescence, vol 2005. Springer, Boston, MA. https://doi.org/10.1007/0-387-23690-2_7

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