Epidural Blood and Fibrin Patches

  • Lisa Watanabe


Both epidural blood patch and fibrin glue patch injections may be useful in the treatment of CSF leaks. The fibrin glue patch has a more rapid and greater adhesive effect than the autologous blood patch. It is also readily available and may be useful when injection of autologous blood is contraindicated. However, autologous blood is inexpensive and raises no risk of allergic reaction or viral infection hazard from a donor. The epidural blood patch has been well documented to be effective in patients with PDPS and SIH. The fibrin patch has been demonstrated to be particularly effective in the event of postsurgical dural tears and may obviate the need for a second surgery in a patient with a postoperative dural leak. The fibrin patch may also be effective in symptomatic patients who are unrelieved by EBP.


Fibrin Glue Autologous Blood Epidural Injection Intracranial Hypotension Dural Puncture 
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© Springer-Verlag New York, Inc. 2004

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  • Lisa Watanabe

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