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Characteristics of Specific Radiopharmaceuticals

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References and Suggested Reading

  • Abrams MJ, Davison A, Jones AG, et al. Synthesis and characterization of hexakis (alkylisocyanide) and hexakis (arylisocyanide complexes of Technetium (I). Inorg Chem. 1983; 22:2798.

    Article  CAS  Google Scholar 

  • Callahan RJ, Froelich JW, McKusick KA, et al. A modified method for the in vivo labeling of red blood cells with Tc-99m: concise communication. J Nucl Med. 1982; 23:315.

    CAS  PubMed  Google Scholar 

  • Dewanjee MK. The chemistry of 99mTc-labeled radiopharmaceuticals. Semin Nucl Med. 1990; 20:5.

    CAS  PubMed  Google Scholar 

  • Eckelman WC, Stiegman J, Paik CH. Radiopharmaceutical chemistry. In: Harpert J, Eckelman WC, Neumann RD, eds, Nuclear Medicine: Diagnosis and Therapy. New York: Thieme Medical; 1996:217.

    Google Scholar 

  • Edwards DS, Cheeseman EH, Watson MW, et al. Synthesis and characterization of technetium and rhenium complexes of N, N’-1, 2-diethylenediylbis-L-cysteine. Neurolites and its metabolites. In: Nicolini M, Bandoli G, Mazzi U, eds. Technetium and Rhenium in Chemistry and Nuclear Medicine. Verona, Italy: Cortina International; 1990; 433.

    Google Scholar 

  • Fritzberg AR, Kasina S, Eshima D, et al. Synthesis and biological evaluation of technetium-99m MAG3 as hippuran replacement. J Nucl Med. 1986; 27:11.

    Google Scholar 

  • Hamacher K, Coenen HH, Stocklin G. Efficient stereospecific synthesis of NCA 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution.J Nucl Med. 1986; 27:235.

    CAS  PubMed  Google Scholar 

  • Hnatowich DJ. Recent developments in the radiolabeling of antibodies with iodine, indium and technetium. Semin Nucl Med. 1990; 20:80.

    CAS  PubMed  Google Scholar 

  • Kabalka GW, Lambrecht RM, Fowler JS, et al. Synthesis of 15O-labelled butanol via organoborane chemistry. Appl Radiat Isot. 1985; 36:853.

    Article  CAS  Google Scholar 

  • Kelly JD, Forster AM, Higley B, et al. Technetium-99m-tetrofosmin as a new radiopharmaceutical for myocardial perfusion imaging. J Nucl Med. 1993; 34:222.

    CAS  PubMed  Google Scholar 

  • Kōhler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975; 256:495.

    Article  PubMed  Google Scholar 

  • Loberg MD, Cooper M, Harvey E, et al. Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid. J Nucl Med. 1976; 17:633.

    CAS  PubMed  Google Scholar 

  • Luxen A, Bida GT, Phelps ME, et al. Synthesis of enantiomerically pure D and L 6-[F-18] fluorodopa and in vivo metabolites via regioselective fluorodemercuration. J Nucl Med. 1987; 28:624.

    Google Scholar 

  • Machulla HJ, Blocher A, Kuntzsch M, et al. Simplified labeling approach for synthesizing 3’-dioxy-3’-[18F] fluorothymidine ([18F] FLT). J Radioanal Nucl Chem. 2000; 243:843.

    Article  CAS  Google Scholar 

  • Meyer GJ, Ostercholz A, Hundeshagen H. 15O-Water constant infusion system for clinical routine application. J Label Comp Radiopharm. 1986; 23:1209.

    Google Scholar 

  • Nunn AD. Radiopharmaceutical for imaging myocardial perfusion. Semin Nucl Med. 1990; 20:111.

    CAS  PubMed  Google Scholar 

  • Package inserts of various kits available from commercial suppliers.

    Google Scholar 

  • Peters AM, Danpure HJ, Osman S, et al. Clinical experience with 99mTc-hexamethyl propylene amine oxime for labeling leukocytes and imaging inflammation. Lancet. 1986; 2:946.

    Article  CAS  PubMed  Google Scholar 

  • Sodd VJ, Allen DR, Hoagland DR, et al., eds. Radiopharmaceuticals II. New York: Society of Nuclear Medicine; 1979.

    Google Scholar 

  • ten Berge RJM, Natarajan AT, Hardenman MR, et al. Labeling with indium-111 has detrimental effects on human lymphocytes. J Nucl Med. 1983; 24:615.

    PubMed  Google Scholar 

  • Thakur ML, Coleman RE, Welch MJ. Indium-111-labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution and comparison with gallium-67 citrate in dogs. J Lab Clin Med. 1977; 82:217.

    Google Scholar 

  • Troutner DR, Volkert WA, Hoffman TJ, et al. A neutral lipophilic complex of Tc-99m with a multidentate amine oxime. Int J Appl Radiat Isot. 1984; 35:467.

    Article  CAS  PubMed  Google Scholar 

  • U.S. Pharmacopeia 26 & National Formulary 21. United States Pharmacopeial Convention, Rockville, MD; 2003.

    Google Scholar 

  • Vanzelto G, Fagret D, Pasqualini R, et al. Biodistribution, dosimetry and safety of myocardial perfusion agent 99mTc-N-NOET in healthy volunteers. J Nucl Med. 2000; 41:141.

    Google Scholar 

  • Welch MJ, ed. Radiopharmaceuticals and Other compounds Labelled with Short-Lived Radionuclides. New York: Pergamon Press; 1977.

    Google Scholar 

  • Zuckier LS, Rodriguez LD, Scharff MD. Immunologic and pharmacologic concepts of monoclonal antibodies. Semin Nucl Med. 1990; 20:166.

    Google Scholar 

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(2004). Characteristics of Specific Radiopharmaceuticals. In: Fundamentals of Nuclear Pharmacy. Springer, New York, NY. https://doi.org/10.1007/0-387-21702-9_7

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  • DOI: https://doi.org/10.1007/0-387-21702-9_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-40360-1

  • Online ISBN: 978-0-387-21702-4

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