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Chlamydia Detection in Blood

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Chlamydia pneumoniae Infection and Disease

Part of the book series: Infectious Agents and Pathogenesis ((IAPA))

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Conclusions

It has been widely believed that the blood of healthy individuals should be germ-free. However, as discussed in this chapter at least a significant fraction of the healthy population carries C. pneumoniae in their blood without any clinical symptoms. Because the detection of bacterial antigen, including DNA, in blood may not prove the viability of the bacteria, validation of viability of the organisms determined by PCR is essential for study of Chlamydia infection in certaininflammatory diseases, including atherosclerosis. In addition, the level of C. pneumoniae in blood is also important in determining whether this bacterium is involved in certain diseases because healthy subjects also carry this pathogen in their blood. Thus, there are still many questions which are currently being investigated by several study groups, including ours.

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Author information

Authors and Affiliations

  1. Division of Molecular Microbiology, Department of Basic Laboratory Sciences, Graduate School of Medicine, Osaka University, Osaka, Japan

    Yoshimasa Yamamoto

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  1. Yoshimasa Yamamoto
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Editors and Affiliations

  1. University of South Florida College of Medicine, Tampa, Florida

    Herman Friedman

  2. Osaka University, Osaka, Japan

    Yoshimasa Yamamoto

  3. University of Pisa, Pisa, Italy

    Mauro Bendinelli

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Yamamoto, Y. (2005). Chlamydia Detection in Blood. In: Friedman, H., Yamamoto, Y., Bendinelli, M. (eds) Chlamydia pneumoniae Infection and Disease. Infectious Agents and Pathogenesis. Springer, Boston, MA. https://doi.org/10.1007/0-306-48741-1_6

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  • DOI: https://doi.org/10.1007/0-306-48741-1_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-48487-2

  • Online ISBN: 978-0-306-48741-5

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