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Micrometastasis pp 139–172Cite as

Clinical Relevance of Tumor Cell Dissemination in Colorectal, Gastric and Pancreatic Carcinoma

  • Chapter

Part of the Cancer Metastasis - Biology and Treatment book series (CMBT,volume 5)

Abstract

Metastatic spread is a major factor in the prognosis of cancer patients. Early detection and eradication of circulating tumor cells prior to the development of metastases could help to improve the outcome of patients after tumor resection. Disseminated tumor cells have been detected in different compartments of the body using cytological and immunostaining methods and, more recently, using different molecular biological techniques. However, the specificity and the sensitivity of the methods and their prognostic impact are still being debated. This chapter gives an overview over the published studies regarding the prognostic relevance of the detection of disseminated tumor cells in lymph nodes, bone marrow, blood and peritoneal cavity in colorectal, gastric and pancreatic carcinoma patients.

Keywords

  • Gastric Cancer
  • Gastric Carcinoma
  • Colorectal Carcinoma
  • Pancreatic Carcinoma
  • Circulate Tumor Cell

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  1. Molecular Oncology Research Group, Department for General and Thoracic Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

    Ilka Vogel & Holger Kalthoff

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Vogel, I., Kalthoff, H. (2003). Clinical Relevance of Tumor Cell Dissemination in Colorectal, Gastric and Pancreatic Carcinoma. In: Pantel, K. (eds) Micrometastasis. Cancer Metastasis - Biology and Treatment, vol 5. Springer, Dordrecht. https://doi.org/10.1007/0-306-48355-6_8

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