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The Sepsis Text pp 769–785Cite as

The Place of Immunonutrition

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Conclusion

While there has been much progress toward understanding the relationship between route and type of nutrition and its effects upon the immune system, the field is still relatively young. Several clinical studies have shown that enteral supplementation with immune-enhancing nutrients can be beneficial in certain subpopulations. In particular, moderate to severely injured trauma patients who are expected to survive their injuries and patients undergoing elective upper GI surgery who are at risk of malnutrition-related complications appear to benefit from these supplemented diets. More study is necessary in patient populations with head injuries, burns, or medical ICU patients in order to determine the usefulness of immune-enhancing diets in these settings. In particular, more study must be directed to determining the correct dose and length of therapy required for these diets to be effective. Further study is necessary to define any increased inflammatory response or mortality rates in a small group of patients with preexisting inflammatory responses or sepsis.

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Authors
  1. Ben L. Zarzaur
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  2. Kenneth A. Kudsk
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme University Hospital, Brussels, Belgium

    Jean-Louis Vincent M.D.

  2. Service de Réanimation Polyvalente, Hôpital Saint-Joseph, Paris, France

    Jean Carlet M.D.

  3. Division of Infectious Diseases, The Memorial Hospital of Rhode Island, Pawtucket, RI

    Steven M. Opal M.D.

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© 2002 Kluwer Academic Publishers

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Zarzaur, B.L., Kudsk, K.A. (2002). The Place of Immunonutrition. In: Vincent, JL., Carlet, J., Opal, S.M. (eds) The Sepsis Text. Springer, Boston, MA. https://doi.org/10.1007/0-306-47664-9_45

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  • DOI: https://doi.org/10.1007/0-306-47664-9_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-7620-0

  • Online ISBN: 978-0-306-47664-8

  • eBook Packages: Springer Book Archive

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