Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Benz, R., Jung, G. and Sahl, H.-G. (1991) Mechanism of channel-formation by lantibiotics in black lipid nienibranes in Jung, G. and Sahl, H.-G. (eds.), Nisin and Novel Lantibiotics, ESCOM, Leiden, pp. 359–372.
Börtz, H., Bierbaum, K., Reynolds, P.E. and Sahl, H.-G. (1997) The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation, Eur. J. Biochem. 246, 193–199.
Börtz, H., Bierbaum, G., Leopold, K., Reynolds, P.E. and Said H.-G. (1998) The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II, Antimicrob. Agents Chemother. 42, 154–160.
Bierbaum, G., Götz, F., Peschcl, A., Kupke, T., van de Kamp, M. and Sahl, H.-G. (1996) The biosythesis of the lantibiotics epiderinin, gallidermin, Pep5 and epilancin K7, Antonie von Leeuwenhoek 69, 119–127.
Breckel, A., Harder, M., Fiedler, H.-P. and Zahner, H. (1995) Production of gallidermin by Staphylococcus gallinarum Tü3928, in Schmid, R.D. (Ed.), Biochemical Engeneering 3, Kurz, Stuttgart, pp 62–66.
Devrieses, L.A., Poutrel, B., Kilpper-Bälz, R. and Schleifer, K.H. (1983) Staphylococcus gallinarum and Stuphylococcus caprae, two new species from animals, Int. J. Syst. Bacteriol. 33, 480–486.
Goldberg, D.E. (1989) Genetic Algorithms in Search, Optimization and Machine Learning, Addison-Welsley Publishing, Reading, Massachusetts.
Hörner, T., Ungermann, V., Zähner, H., Fiedler, H.-P., Utz, R., Kellner, R. and Jung G. (1990) Comparative studies on the fermentative production of lantibiotics by staphylococci, Appl. Microbiol. Biotechn. 32, 511–517.
Holland, J.H. (1992) Genetische Algorithmen, Spekt. Wiss. 9.
Hosobuchi. M. and Yoshikawa. H. (1999) Scale-up of microbial processes, in Demain, A.L. and Davies, J.E. (eds.), Manual of Industrial Microbiology and Biotechnology, 2nd edn., ASM Press, Washington, pp 236–239.
Humphry, A. (1998) Shake tlask to fermentor: what have we learned? Biotechno. Prog. 14, 3–7.
Jack, R.W., Bierbaum, G. and Sahl, H.-G. (1998) Lantibiotics and Related Peptides, Springer-Verlag, Heidelberg.
Jung, G. (1991) Lantibiotics: a survey, in Jung, G. and Sahl, H.-G. (eds.), Nisin and Novel Lantibiotics, ESCOM, Leiden, pp. 1–34.
Kellner, R., Jung, G., Hörner, T., Zahner, H., Schnell, N., Entian, K.-D. and Götz, F. (1988) Gallidermin: a new lanthionine-containing polypeptide antibiotic, Eur. J. Biochem. 177, 53–59.
Kempf, M., Theobald, U. and Fiedler H.-P. (1999a) Economic improvement ofthe fermentative production of gallidermin by Staphylococcus gallinarum, Biotechnology Letters 21, 663–667.
Kempf, M., Theobald, U. and Fiedler H.-P. (1999b) Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum, Biotechnology Letters 21, 959–963.
Kempf, M., Theobald, U. and Fiedler H.-P. (2000) Production ofthe antibiotic gallidermin by Staphylococcus gallinarum—development of a scale-up procedure, Biotechnology Letters 22, 123–128.
Kempf, M., Theobald, U. and Fiedler, H.-P. (1997) Influence of dissolved oxygen on the fermentativ production of gallidermin by Staphylococcus gallinarum, Biotech Letters 19, 1063–1065.
Omura, S. and Tanaka, Y, (1984) Control of ammonium ion level in antibiotic fermentation, in Ortiz-Ortiz, L., Bojalil, L.F. and Yakoleff, V. (eds.), Biological, Biochemical and Biomedical Aspects of Actinomycetes, Academic Press, Orlando, p. 367.
Reuss, M. and Bajpai, R. (1991) Stirred tank models, in Rehm. H.-J. and Reed. G. (eds.), Biotechnology Vol. 4, 2nd edn., VCH, Weinheim, pp 299–348.
Sahl, H.-G., Jack, R., Bierbaum, G. (1995) Biosynthesis and biological activities of lantibiotics with unique post-translational modifications, Eur. J Biochem. 230, 827–853.
Sanglier, J.J., Wellington, E.M.H., Behal, V., Fiedler, H.P., Ellouz Ghorbel, R., Finance, C., Hacene, M., Kamoun, A., Kelly, C., Mercer, D.K., Prinzis, S. and Trigo, S. (1993) Novel bioactive compounds from actinomycetes, Res. Microbiol. 144, 661–663.
Theobald, U. and Kempf M. (1998) A novel tool for medium optimization and characterization in the early stages of a metabolite production process, Biotechnology Techniques 12, 893–897.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Kluwer Academic Publishers
About this chapter
Cite this chapter
Kempf, M., Theobald, U., Fiedler, HP. (2001). The Antibiotic Gallidermin-Evolution of a Production Process. In: Van Broekhoven, A., Shapiro, F., Anné, J. (eds) Novel Frontiers in the Production of Compounds for Biomedical Use. Focus on Biotechnology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/0-306-46885-9_3
Download citation
DOI: https://doi.org/10.1007/0-306-46885-9_3
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-6747-5
Online ISBN: 978-0-306-46885-8
eBook Packages: Springer Book Archive