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Transcriptional Organisation and Regulation of E. coli Group 2 Capsule Expression

  • Ian S. Roberts
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 485)

Conclusion

Therefore as a consequence of our studies to date a picture is beginning to emerge of a complex integrated regulatory system involving a number of interacting regulatory proteins and over-arching regulatory control circuits (Fig. 1). The key questions that we need to address are how is transcription from the region 1 and 3 promoters co-ordinated? What is the role of global regulators such as H-NS in repressing transcription at 20ºC? How is capsule expression regulated in vivo and is capsule expression co-ordinated with the expression of other cell surface structures involved in disease?Answering these questions represents a fascinating biological problem.

Keywords

Polysialic Acid Integration Host Factor Transcriptional Organisation Capsule Gene Capsule Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Ian S. Roberts
    • 1
  1. 1.School of Biological SciencesUniversity of ManchesterManchesterUK

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