Skip to main content
SpringerLink
Log in

Vasostatins

Vascular Targets

  • Chapter
Chromogranins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 482))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aardal S., and Helle K.B., 1992, The vasoinhibitory activity of bovine chromogranin A fragments (vasostatin) and its independence of extracellular calcium in isolated segments ofhuman blood vessels. Regul. Pept.. 41: 9–18

    Article  PubMed  CAS  Google Scholar 

  • Aardal S., Helle K.B., Elsayed S., Reed R.K., and Serck-Hansen G., 1993, Vasostatins, comprising the N-terminal domain of chromogranin A, suppress tension in isolated human blood vessel segments. JNeuroendocrinol. 5: 105–112.

    Google Scholar 

  • Aardal, S., Helle, K.B., and Svensen, S., 1991, In vitro responses to atrial natriuretic polypeptide in human vessels commonly used as aortocoronaary bypass grafts. Scand.J. Thor.Cardiovasc.Surg. 26:135–141.

    Google Scholar 

  • Aardal, S., Aardal, N.P., Larsen, T.H., Angeletti, R.H., Stridsberg, M., Taupenot, L., Aunis, D., and K.B. Helle, 1996, Human pheochromocytoma: different patterns of catecholamines and chromogranins in the intact tumor, urine and serum in clinically unsuspected cases. Scand.J. Clin. Lab. Inv. 56:511–523.

    Article  CAS  Google Scholar 

  • Angeletti R.H., Aardal S., Serck-Hansen G., Gee P., and Helle K.B., 1994,. Vasoinhibiting activity of the synthetic peptides from the amino terminus of the adrenomedullary chromogranin A. Acta Physiol Scand. 152: 11–19

    PubMed  CAS  Google Scholar 

  • Angeletti RH, Mints L., Aber C., and Russel J., 1996, Determination of residues in chromogranin A (1 6-40) required for inhibition of parathyroid hormone secretion. Endocrinol 137: 2918–2922

    Article  CAS  Google Scholar 

  • Angeletti, R.H., Zouhheiry, H., D’Amico, T., and Russel J., 1997, Regulation of parathyroid secretion by chromogranin A amino terminal peptides. In Neurochemistry: Cellular, Molecular and Clinical aspects (Eds: Korf J, Teelken AW). Plenum Press. pp 583–588.

    Google Scholar 

  • Benedum, U.,, Bauerle, P., Konecki, D., Frank, R., Powell, J., Mallet, J., and Huttner, W.J., 1986, The primary structure of bovine chromogranin A: a representative for a class of acidic secretory proteins common to a variety ofpeptidergic cells. EMBO J. 5, 1495–1502.

    PubMed  CAS  Google Scholar 

  • Benedum, U., Lamoroux, A., Konecki, D., Rosa, P., Hille, A., Baauerle, P., Frank, R., Lottspeich, F., Mallet, J., and Huttner, W. 1987, The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region. EMBO J. 6: 1203–1211.

    PubMed  CAS  Google Scholar 

  • Bevan J.A., and Bevan D.R., 1988, Changes in arteries as they get smaller. In: Vasodilation: Vascular smooth muscle, peptides, autonomic nerves and endothelium, Edited by Vanhoutte P., Raven Press, Ltd. New York: 55–60

    Google Scholar 

  • Cryer, P.E., Wortman, J., Sha S.D., Nowak R.M., and Deftos L.J., 1991, Plasma chromogranin A as a marker for sympathochromaffin activity in humans. Am J. Physiol 260:E243–246

    PubMed  CAS  Google Scholar 

  • Daut, J., Standen, N.B., and Nelson, M.T. 1994, The role of the membrane potential of endothelial and smooth muscle cells in the regulation of coronary blood flow. J. Cardiovasc.Electrophysiol. 5: 154–181

    PubMed  CAS  Google Scholar 

  • DeFily, D.V., and Chilian, W.M., 1995, Coronary microcirculation: autoregulation and metabolic control. BasicRes. Cardiol. 90: 112–118.

    CAS  Google Scholar 

  • Dillen, L., DeBlock, J., van Lear, L. and De Potter, W., 1989, Enzyme-linked immunosorbent assay for chromogranin A. Clin. Chem. 35: 1934–1938.

    PubMed  CAS  Google Scholar 

  • Halpem W., Osol G., and Coy G.S., 1984,. Mechanical behavior of pressurized in-vitro prearteriolar vessels determined with a video system. Annals ofBiomedical Engineering. 12: 463–479.

    Google Scholar 

  • Helle, K.B., and Angeletti, R.H. 1998 Chromogranins as multifunctional prohormones: A role in protection against excessive responses to stress? In Kanno, T. et al (Eds): The Adrenal Chromaffin Cell: Archetype and Exemplar of Cellular Signalling in Secretory Control. Hokkaido University Press, Sapporo, Japan, pp 273–281.

    Google Scholar 

  • Helle, K.B., Marley, P.D., Angeletti, R.H., Aunis, D., Galindo, E., Small, D.H, and Livett, B.G., 1993, Chromogranin A: secretion of processed products from the stimulated retrogradely perfused bovine adrenal gland. J Neuroendocrinol 5: 413–420

    PubMed  CAS  Google Scholar 

  • Highsmith, R.F., Blackburn, K., and Schmidt, D.J., 1992, Endothelin and calcium dynamics in vascular smooth muscle. Ann. Rev. Physiol. 54: 257–277.

    Article  CAS  Google Scholar 

  • Hutton, J.C., Davidson, H.W., and Peshevaria, M., 1987, Proteolytic processing of chromogranin A in purified insulin granules. Formation of a 20 kDa N-terminal fragment (betagranin) by the concerted action of a Ca2+-dependent endopeptidase and carboxypeptidase H. Biochem. J. 244: 457–464.

    PubMed  CAS  Google Scholar 

  • Iacangelo, A., and Eiden, L.E., 1995, Chromogranin A: current status as a precursor for bioactive peptides and a granulogenic/sorting factor in the regulated secretory pathway. Regul. Pept. 58: 65–88.

    Article  PubMed  CAS  Google Scholar 

  • Iacangelo, A., Affolter, H., Eiden, L., Herbert, E., and Grimes, M., 1986. Bovine chromogranin A: its sequence and the distribution of its messenger RNA in tissues. Nature, 323: 82–86.

    Article  PubMed  CAS  Google Scholar 

  • Iacangelo, A. Okayama, H., and Eiden, L.E., 1988. Primary structure of rat chromogranin A and distribution of its mRNA. FEBSLett. 227: 115–121.

    CAS  Google Scholar 

  • Kirkeleit, J., Lugardon, K., Angeletti, R.H., Corti, A., Osol G. J., and Helle, K. B., 2000, Vasodilation by the chromogranin A peptides, CGA1-76 and CGA1-40 in bovine adrenal arteries. Acta Physiol. Scand. Suppl. (ScanPhys2000, Stockholm 16–19 August) Abstract.

    Google Scholar 

  • Konecki, D., Benedum, U., Gerdes, H.-H., and Huttner, W., 1987, The primary structure of human chromogranin A and pancreastatin. J. Biol. Chem. 262: 17026–17030.

    PubMed  CAS  Google Scholar 

  • Liang, F., Dillen L, Zhang, X.Y., Cohen, E.P,, Angeletti, R.H., Claeys, M,, and De Potter, W.P, 1996, Vasostatins, N-terminal products of chromogranin A, are released from the stimulated calf spleen in vitro. Acta Physiol Scand 135: 23–30.

    Google Scholar 

  • Mandala, M., Serck-Hanssen,, Martino, G., and Helle, K. B., 1999, The fluorescent cation dye rhodamine 6G as a probe for membrane potential in bovine aortic endothelial cells. Analyt. Biochem.. 274: 1–6.

    PubMed  CAS  Google Scholar 

  • Metz-Boutigue, M.-H., Garcia-Sablone, P., Angeletti., R.H., and Aunis, D., 1993. Intracellular and extracellular processing of chromogranin A. Determination of cleavage sites. Eur. J. Biochem. 217:247–257.

    Article  PubMed  CAS  Google Scholar 

  • Miller, V.M., Komori, K., Burnett jr., J.C., and Vanhoutte, P.M., 1989, Differential sensitivity to endothelin in canine arteries and veins. Am. JPhysiol, 257: H1127–HI 13 1

    CAS  Google Scholar 

  • Moncada, S., and Vane, J.R. 1979. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin. Pharmacol. Rev. 30: 293–331.

    Google Scholar 

  • Mulvany, M.J., and Aalkjær, C., 1990, Structure and function of small arteries. Physiol Rev. 70: 921–961.

    PubMed  CAS  Google Scholar 

  • Nelson, M.T., Patlak, J.B., Worley, J.F., and Standen N.B., 1990, Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am. J. Physiol. 259: C3–C18.

    PubMed  CAS  Google Scholar 

  • Nelson, M.T., and Quayle J.M., 1995, Physiological roles and properties of potassium channels in arterial smooth muscle. Am JPhysiol. 268: C799–C822.

    CAS  Google Scholar 

  • O’Connor, D.T., and Bernstein, K.N.,( 1984, Radioimmunoassay of chromogranin A in plasma as a meassure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma. N. Engl. J. Med., 311, 764–70.

    Google Scholar 

  • Parmer, R.M., and Moncada, S., 1989, A novel citrullin-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. Biochim. Biophys.Res.Com. 158: 348–352

    Google Scholar 

  • Resink, T.J., Scott-Burden, S., Boulanger, C., Weber, E., and Bohler, F.R-1990, Internalisation of endothelin by cultured human vascular smooth muscle cells: characterization and physiological significance. Mol. Pharmacol. 38:244–252.

    PubMed  CAS  Google Scholar 

  • Russel,, J., Gee, P., Liu, S.M., and Angeletti, R.H., 1994, Inhibition of parathyroid hormone secretion by aminoterminalchromogranin peptides. Endocrinol. 135: 337–342

    Google Scholar 

  • Stridsberg, M., Øberg, K., Li, Q., Engstrom, U., and Lundqvist, G., 1995, Measurements of chromogranin A, chromogranin B (secretogranin I), chromogranin C (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours. J. Endocrinol. 144: 49–59.

    Article  PubMed  CAS  Google Scholar 

  • Stridsberg, M., Angeletti, R.H., and Helle, K.B., 2000, Quantitation of chromogranin A and chromograninBin mammals: molecular characterizationand comparative aspects. J. Endocrinol. In press.

    Google Scholar 

  • Strub, J.M., Garcia-Sablone, P., Lonning, K., Taupenot, L., Hubert, P., van Dorsselaer, A., Aunis, D., and Metz-Boutigue, M.-H., 1995, Processing of chromogranin B in bovine adrenal medulla: Identification of secretolytin, the endogenous 614–626 C-terminal fragment with antibacterial activity. Eur. J. Biochem. 229: 356–368

    Article  PubMed  CAS  Google Scholar 

  • Yaganisawa, M., Kurihara, H., and Kimura, S., 1988, A novel, potent vasoconstrictor peptide produced by vascular endothelial cells. Nature, 332: 411–415.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, University of Bergen, 5000, Bergen, Norway 1

    Karen B. Helle

Authors
  1. Karen B. Helle
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Bergen, Bergen, Norway

    Karen B. Helle

  2. INSERM U338, Centre of Neurochemistry, Strasbourg, France

    Dominique Aunis

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Kluwer Academic Publishers

About this chapter

Cite this chapter

Helle, K.B. (2002). Vasostatins. In: Helle, K.B., Aunis, D. (eds) Chromogranins. Advances in Experimental Medicine and Biology, vol 482. Springer, Boston, MA. https://doi.org/10.1007/0-306-46837-9_18

Download citation

  • DOI: https://doi.org/10.1007/0-306-46837-9_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46446-1

  • Online ISBN: 978-0-306-46837-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation