The Role of C-type Lectins in the Innate Immunity Against Pulmonary Pathogens

Athamana, A., Ofek, I., Keisari, Y., Markowitz, S., Dutton, G. S., and Sharon, N. 1991. Lectinophagocytosis of encapsulated Klebsiella pneumoniae mediated by surface lectin of guinea pig alveolar macrophages and human-monocyte-derived macrophages. Infect. Immun. 59:1673–1682 (1991)Google Scholar

Baltimore R.S., Duncan R.L., Shapiro E.D., and Edberg S. C. 1989. Epidemiology of pharyngeal colonization of infants with aerobic gram-negative rod bacteria. J. Clin. Microbiol 27:91–95PubMedGoogle Scholar

Doebbeling, B.N., Epidemics: identification and management, in Prevention and control of nosocomial infections, R.P. Wenzel, Editor. 1993, Williams & Wilkins: Baltimore. p. 177–206.Google Scholar

Favre-Bonte, S., B. Joly, and C. Forestier. 1999. Consequences of reduction of Klebsiella pneumoniae capsule expression on interaction of this bacterium with epithelial cells. Infect. Immun. 67:554–561PubMedGoogle Scholar

Holst O., and Brade H. 1992. Chemical structure of the core region of lipopolysaccharides. In Bacterial Endotoxic Lipopolysaccharides (D.C. Morisson and L.L. Ryan, eds) Vol I, CRC Press, Boca Raton, FL, pp135–170.Google Scholar

Karunarante, D. N.: Structural investigation of the capsular polysaccharides of K. pneumoniae. PhD Thesis. Univ. British Columbia, Vancouver: Canada 1985Google Scholar

Kenne, L., Lindberg, B.: Bacterial polysaccharides. In: Aspinall, G. O., and Lindberg, B. (Eds): The Polysaccharides. 2:287–363. New-York: Acad. Press, Inc. 1983.Google Scholar

Kuan, S.F., K. Rust. and E. Crouch. 1992. Interactions of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia coli-binding protein in bronchoalveolar lavage. J.Clin.Invest. 90:97–103PubMedCrossRefGoogle Scholar

Lim, B.L., J.Y. Wang, U. Holmskov, H.J. Hoppe, and K.B. Reid. 1994. Expression of the carbohydrate recognition domain of lung surfactant protein D and demonstration of its binding to lipopolysaccharides of gram-negative bacteria. Biochem.Biophys.Res.Commun. 202: 1674–1678PubMedCrossRefGoogle Scholar

Matatov, R., J. Goldhar, E. Skutelsky, I. Sechter, R. Perry, R. Podschun, H. Sahly, K. Thankavel, S. N. Abraham, and I. Ofek. 1999. Encapsulated klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface. FEMS Microbiol. Letters 179: 123–130.CrossRefGoogle Scholar

Ofek, I., and E. Crouch. 2000. Interaction of microbial glycoconjugates with collectins: implications for pulmonary host defence. In Glycobiology (R. J. Doyle, ed) Kluwer-Plenum Co. London. (in press)Google Scholar

Ofek, I., K. Kabha, Y. Keisari, J. Schlepper-Schaefer, S.N. Abraham, D. McGregor, D. Chang, and E. Crouch. 1997. Recognition of Klebsiella pneumoniae by pulmonary C-type lectins. Nova Acta Leopold.NF 75:43–48 Google Scholar

Ofek, I., Kabha, K., Athamna, A., Frankel, G., Wozniak, D. J., Hasty, L. D. and Ohman, E. D. 1993. Genetic exchange of determinants for capsular polysaccharide biosynthesis between Klebsiella pneumoniae strains expressing serotypes K2 and K21a. Infect. Immun. 61:4208–4216PubMedGoogle Scholar

Podschun, R. and U. Ullmann,l998KlebsielIa spp. as nosocomial pathogen: Epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev, 11:589–603Google Scholar

Schelenz, S., R. Malhotra, R.B. Sim, U. Holmskov, and G.J. Bancroft. 1995. Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an agglutinin for acapsular yeast cells. Inlfect.Immunol. 63:3360–3368Google Scholar

Susskind M., S. Muller-Loennies, W. Nimmich, H. Brade, and O. Holst. 1995. Structural investigation on the carbohydrate backbone of the lipopolysaccharide from KIebsiella pneumoniae rough mutant R20/01-. Carbohydrate Res. 269:C1–C7.CrossRefGoogle Scholar

Valenti, W.M., Trudell R.G. and Bentley D.W. 1978. Factors predisposing to ortopharyngeal colonization with gram-negative bacilli in the aged. N. Engl. J. Med. 298: 1108–1111PubMedCrossRefGoogle Scholar

Weiss, J., Hutzler, M., and Kao, L. 1986. Environmental modulation of lipopolysaccharide chain length alters the sensitivity of Escherichia coli to the neutrophil bactericidal/permeability-increasing protein. Infect.Immunol. 51:594–599Google Scholar