Extreme Environments as a Resource for Microorganisms and Novel Biocatalysts

  • Garabed Antranikian
  • Constantinos E. Vorgias
  • Costanzo Bertoldo
Chapter
Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 96)

Abstract

The steady increase in the number of newly isolated extremophilic microorganisms and the discovery of their enzymes by academic and industrial institutions underlines the enormous potential of extremophiles for application in future biotechnological processes. Enzymes from extremophilic microorganisms offer versatile tools for sustainable developments in a variety of industrial application as they show important environmental benefits due to their biodegradability, specific stability under extreme conditions, improved use of raw materials and decreased amount of waste products. Although major advances have been made in the last decade, our knowledge of the physiology, metabolism, enzymology and genetics of this fascinating group of extremophilic microorganisms and their related enzymes is still limited. In-depth information on the molecular properties of the enzymes and their genes, however, has to be obtained to analyze the structure and function of proteins that are catalytically active around the boiling and freezing points of water and extremes of pH. New techniques, such as genomics, metanogenomics, DNA evolution and gene shuffling, will lead to the production of enzymes that are highly specific for countless industrial applications. Due to the unusual properties of enzymes from extremophiles, they are expected to optimize already existing processes or even develop new sustainable technologies.

Extremophiles Stable biocatalysts Thermophiles Extremes of pH Psychrophiles Enantioselectivity 

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References

  1. 1.
    Woese CR, Kandler O, Wheelis ML (1990) Proc Natl Acad Sci USA 87:4576 PubMedGoogle Scholar
  2. 2.
    Woese CR, Achenbach L, Rouviere P, Mandelco L (1991) Syst Appl Microbiol 14:364 PubMedGoogle Scholar
  3. 3.
    Lorenz P, Liebeton K, Niehaus F, Eck J (2002) Curr Opin Biotechnol 13:572 CrossRefPubMedGoogle Scholar
  4. 4.
    Kauffmann IM, Schmitt J, Schmid RD (2004) Appl Microbiol Biotechnol 64:665 CrossRefPubMedGoogle Scholar
  5. 5.
    Beja O (2004) Curr Opin Biotechnol 15:187 CrossRefPubMedGoogle Scholar
  6. 6.
    Beja O, Suzuki MT, Heidelberg JF, Nelson WC, Preston CM, Hamada T, Eisen JA, Fraser CM, DeLong EF (2002) Nature 415:630 CrossRefPubMedGoogle Scholar
  7. 7.
    Beja O, Koonin EV, Aravind L, Taylor LT, Seitz H, Stein JL, Bensen DC, Feldman RA, Swanson RV, DeLong EF (2002) Appl Environ Microbiol 68:335 CrossRefPubMedGoogle Scholar
  8. 8.
    Beja O, Suzuki MT, Koonin EV, Aravind L, Hadd A, Nguyen LP, Villacorta R, Amjadi M, Garrigues C, Jovanovich SB, Feldman RA, DeLong EF (2000) Environ Microbiol 2:516 CrossRefPubMedGoogle Scholar
  9. 9.
    Beja O, Aravind L, Koonin EV, Suzuki MT, Hadd A, Nguyen LP, Jovanovich SB, Gates CM, Feldman RA, Spudich JL, Spudich EN, DeLong EF (2000) Science 289:1902 CrossRefPubMedGoogle Scholar
  10. 10.
    Henne A, Schmitz RA, Bomeke M, Gottschalk G, Daniel R (2000) Appl Environ Microbiol 66:3113 CrossRefPubMedGoogle Scholar
  11. 11.
    Healy FG, Ray RM, Aldrich HC, Wilkie AC, Ingram LO, Shanmugam KT (1995) Appl Microbiol Biotechnol 43:667 PubMedGoogle Scholar
  12. 12.
    Richardson TH, Tan X, Frey G, Callen W, Cabell M, Lam D, Macomber J, Short JM, Robertson DE, Miller C (2002) J Biol Chem 277:26 501 Google Scholar
  13. 13.
    Cottrell MT, Moore JA, Kirchman DL (1999) Appl Environ Microbiol 65:2553 PubMedGoogle Scholar
  14. 14.
    Cottrell MT, Wood DN, Yu L, Kirchman DL (2000) Appl Environ Microbiol 66:1195 CrossRefPubMedGoogle Scholar
  15. 15.
    Rondon MR, Raffel SJ, Goodman RM, Handelsman J (1999) Proc Natl Acad Sci USA 96:6451 CrossRefPubMedGoogle Scholar
  16. 16.
    Rondon MR, August PR, Bettermann AD, Brady SF, Grossman TH, Liles MR, Loiacono KA, Lynch BA, MacNeil IA, Minor C, Tiong CL, Gilman M, Osburne MS, Clardy J, Handelsman J, Goodman RM (2000) Appl Environ Microbiol 66:2541 CrossRefPubMedGoogle Scholar
  17. 17.
    Torsvik V, Ovreas L (2002) Curr Opin Microbiol 5:240 CrossRefPubMedGoogle Scholar
  18. 18.
    Torsvik V, Ovreas L, Thingstad TF (2002) Science 296:1064 CrossRefPubMedGoogle Scholar
  19. 19.
    Entcheva P, Liebl W, Johann A, Hartsch T, Streit WR (2001) Appl Environ Microbiol 67:89 CrossRefPubMedGoogle Scholar
  20. 20.
    Voget S, Leggewie C, Uesbeck A, Raasch C, Jaeger KE, Streit WR (2003) Appl Environ Microbiol 69:6235 CrossRefPubMedGoogle Scholar
  21. 21.
    Lorenz P, Scleper C (2002) J Mol Catal B 19–20:13 CrossRefGoogle Scholar
  22. 22.
    Morita RY (1975) Bacteriol Rev 39:144 PubMedGoogle Scholar
  23. 23.
    Gerday C, Aittaleb M, Bentahir M, Chessa JP, Claverie P, Collins T, D'Amico S, Dumont J, Garsoux G, Georlette D, Hoyoux A, Lonhienne T, Meuwis MA, Feller G (2000) Trends Biotechnol 18:103 CrossRefPubMedGoogle Scholar
  24. 24.
    Lonhienne T, Gerday C, Feller G (2000) Biochim Biophys Acta 1543:1 PubMedGoogle Scholar
  25. 25.
    Stetter KO (1996) Ciba Found Symp 202:1 Google Scholar
  26. 26.
    Huber R, Huber H, Stetter KO (2000) FEMS Microbiol Rev 24:615 CrossRefPubMedGoogle Scholar
  27. 27.
    Segerer AH, Burggraf S, Fiala G, Huber G, Huber R, Pley U, Stetter KO (1993) Orig Life Evol Biosph 23:77 CrossRefPubMedGoogle Scholar
  28. 28.
    Stetter KO (1999) FEBS Lett 452:22 CrossRefPubMedGoogle Scholar
  29. 29.
    Lien T, Madsen M, Rainey FA, Birkeland NK (1998) Int J Syst Bacteriol 48 Pt 3:1007 Google Scholar
  30. 30.
    Woese CR, Fox GE (1977) Proc Natl Acad Sci USA 74:5088 PubMedGoogle Scholar
  31. 31.
    Jan RL, Wu J, Chaw SM, Tsai CW, Tsen SD (1999) Int J Syst Bacteriol 49 Pt 4:1809 Google Scholar
  32. 32.
    Xiang X, Dong X, Huang L (2003) Extremophiles 7:493 CrossRefPubMedGoogle Scholar
  33. 33.
    He ZG, Zhong H, Li Y (2004) Curr Microbiol 48:159 CrossRefPubMedGoogle Scholar
  34. 34.
    Searcy DG, Stein DB (1980) Biochim Biophys Acta 609:180 PubMedGoogle Scholar
  35. 35.
    Schleper C, Puehler G, Holz I, Gambacorta A, Janekovic D, Santarius U, Klenk HP, Zillig W (1995) J Bacteriol 177:7050 PubMedGoogle Scholar
  36. 36.
    Smith PF (1980) Biochim Biophys Acta 619:367 PubMedGoogle Scholar
  37. 37.
    van de Vossenberg, Driessen AJ, Zillig W, Konings WN (1998) Extremophiles 2:67 CrossRefPubMedGoogle Scholar
  38. 38.
    Futterer O, Angelov A, Liesegang H, Gottschalk G, Schleper C, Schepers B, Dock C, Antranikian G, Liebl W (2004) Proc Natl Acad Sci USA 101:9091 CrossRefPubMedGoogle Scholar
  39. 39.
    Bandeiras TM, Salgueiro CA, Huber H, Gomes CM, Teixeira M (2003) Biochim Biophys Acta 1557:13 PubMedGoogle Scholar
  40. 40.
    Nemati M, Lowenadler J, Harrison ST (2000) Appl Microbiol Biotechnol 53:173 CrossRefPubMedGoogle Scholar
  41. 41.
    Burton NP, Williams TD, Norris PR (1999) Arch Microbiol 172:349 CrossRefPubMedGoogle Scholar
  42. 42.
    Gomes CM, Huber H, Stetter KO, Teixeira M (1998) FEBS Lett 432:99 CrossRefPubMedGoogle Scholar
  43. 43.
    Brierley CL, Brierley JA (1973) Can J Microbiol 19:183 PubMedGoogle Scholar
  44. 44.
    Kurosawa N, Itoh YH, Itoh T (2003) Int J Syst Evol Microbiol 53:1607 CrossRefPubMedGoogle Scholar
  45. 45.
    Krulwich TA, Guffanti AA, Ito M (1999) Novartis Found Symp 221:167 PubMedGoogle Scholar
  46. 46.
    Horikoshi K (1999) Microbiol Mol Biol Rev 63:735 PubMedGoogle Scholar
  47. 47.
    Jones BE, Grant WD, Duckworth AW, Owenson GG (1998) Extremophiles 2:191 CrossRefPubMedGoogle Scholar
  48. 48.
    Wiegel J, Kevbrin VV (2004) Biochem Soc Trans 32:193 CrossRefPubMedGoogle Scholar
  49. 49.
    Prowe SG, Antranikian G (2001) Int J Syst Evol Microbiol 51:457 PubMedGoogle Scholar
  50. 50.
    Engle M, Li Y, Woese C, Wiegel J (1995) Int J Syst Bacteriol 45:454 PubMedGoogle Scholar
  51. 51.
    Keller M, Braun FJ, Dirmeier R, Hafenbradl D, Burggraf S, Rachel R, Stetter KO (1995) Arch Microbiol 164:390 CrossRefPubMedGoogle Scholar
  52. 52.
    Dirmeier R, Keller M, Hafenbradl D, Braun FJ, Rachel R, Burggraf S, Stetter KO (1998) Extremophiles 2:109 CrossRefPubMedGoogle Scholar
  53. 53.
    Litchfield CD, Gillevet PM (2002) J Ind Microbiol Biotechnol 28:48 Google Scholar
  54. 54.
    Sanchez-Porro C, Martin S, Mellado E, Ventosa A (2003) J Appl Microbiol 94:295 CrossRefPubMedGoogle Scholar
  55. 55.
    Ventosa A, Marquez MC, Garabito MJ, Arahal DR (1998) Extremophiles 2:297 CrossRefPubMedGoogle Scholar
  56. 56.
    Ollivier B, Caumette P, Garcia JL, Mah RA (1994) Microbiol Rev 58:27 PubMedGoogle Scholar
  57. 57.
    Ventosa A, Nieto JJ, Oren A (1998) Microbiol Mol Biol Rev 62:504 PubMedGoogle Scholar
  58. 58.
    Liebl W (2001) Methods Enzymol 330:290 PubMedGoogle Scholar
  59. 59.
    Bronnenmeier K, Kern A, Liebl W, Staudenbauer WL (1995) Appl Environ Microbiol 61:1399 PubMedGoogle Scholar
  60. 60.
    Bok JD, Yernool DA, Eveleigh DE (1998) Appl Environ Microbiol 64:4774 PubMedGoogle Scholar
  61. 61.
    Te'o VS, Saul DJ, Bergquist PL (1995) Appl Microbiol Biotechnol 43:291 CrossRefPubMedGoogle Scholar
  62. 62.
    Saul DJ, Williams LC, Grayling RA, Chamley LW, Love DR, Bergquist PL (1990) Appl Environ Microbiol 56:3117 PubMedGoogle Scholar
  63. 63.
    Saul DJ, Williams LC, Love DR, Chamley LW, Bergquist PL (1989) Nucleic Acids Res 17:439 PubMedGoogle Scholar
  64. 64.
    Ruttersmith LD, Daniel RM (1991) Biochem J 277 (Pt 3):887 Google Scholar
  65. 65.
    Halldorsdottir S, Thorolfsdottir ET, Spilliaert R, Johansson M, Thorbjarnardottir SH, Palsdottir A, Hreggvidsson GO, Kristjansson JK, Holst O, Eggertsson G (1998) Appl Microbiol Biotechnol 49:277 CrossRefPubMedGoogle Scholar
  66. 66.
    Crennell SJ, Hreggvidsson GO, Nordberg Karlsson E (2002) J Mol Biol 320:883 CrossRefPubMedGoogle Scholar
  67. 67.
    Bauer MW, Driskill LE, Callen W, Snead MA, Mathur EJ, Kelly RM (1999) J Bacteriol 181:284 PubMedGoogle Scholar
  68. 68.
    Moracci M, Ciaramella M, Rossi M (2001) Methods Enzymol 330:201 PubMedGoogle Scholar
  69. 69.
    Bauer MW, Bylina EJ, Swanson RV, Kelly RM (1996) J Biol Chem 271:23 749 Google Scholar
  70. 70.
    Bauer MW, Kelly RM (1998) Biochemistry 37:17 170 CrossRefGoogle Scholar
  71. 71.
    Nucci R, Moracci M, Vaccaro C, Vespa N, Rossi M (1993) Biotechnol Appl Biochem 17 (Pt 2):239 Google Scholar
  72. 72.
    Moracci M, Nucci R, Febbraio F, Vaccaro C, Vespa N, La Cara F, Rossi M (1995) Enzyme Microb Technol 17:992 CrossRefPubMedGoogle Scholar
  73. 73.
    Sivori AS, Mercuri OA, Forchiassin F (1996) Rev Argent Microbiol 28:9 PubMedGoogle Scholar
  74. 74.
    Durrant LR, Mello AB, Reginatto V (1992) Biochem Soc Trans 20:227S PubMedGoogle Scholar
  75. 75.
    Allen WG (1976) Biotechnol Bioeng Symp 6:303 Google Scholar
  76. 76.
    Schulein M (2000) Biochim Biophys Acta 1543:239 PubMedGoogle Scholar
  77. 77.
    Jeffries TW (1996) Curr Opin Biotechnol 7:337 CrossRefPubMedGoogle Scholar
  78. 78.
    Te'o VS, Cziferszky AE, Bergquist PL, Nevalainen KM (2000) FEMS Microbiol Lett 190:13 CrossRefPubMedGoogle Scholar
  79. 79.
    McCarthy AA, Morris DD, Bergquist PL, Baker EN (2000) Acta Crystallogr D Biol Crystallogr 56 (Pt 11):1367 Google Scholar
  80. 80.
    Simpson HD, Haufler UR, Daniel RM (1991) Biochem J 277 (Pt 2):413 Google Scholar
  81. 81.
    Winterhalter C, Heinrich P, Candussio A, Wich G, Liebl W (1995) Mol Microbiol 15:431 PubMedGoogle Scholar
  82. 82.
    Velikodvorskaya TV, Volkov I, Vasilevko VT, Zverlov VV, Piruzian ES (1997) Biochemistry (Mosc) 62:66 PubMedGoogle Scholar
  83. 83.
    Zverlov V, Piotukh K, Dakhova O, Velikodvorskaya G, Borriss R (1996) Appl Microbiol Biotechnol 45:245 CrossRefPubMedGoogle Scholar
  84. 84.
    Walsh DJ, Gibbs MD, Bergquist PL (1998) Extremophiles 2:9 CrossRefPubMedGoogle Scholar
  85. 85.
    Meissner K, Wassenberg D, Liebl W (2000) Mol Microbiol 36:898 CrossRefPubMedGoogle Scholar
  86. 86.
    Lama L, Calandrelli V, Gambacorta A, Nicolaus B (2004) Res Microbiol 155:283 CrossRefPubMedGoogle Scholar
  87. 87.
    Teplitsky A, Mechaly A, Stojanoff V, Sainz G, Golan G, Feinberg H, Gilboa R, Reiland V, Zolotnitsky G, Shallom D, Thompson A, Shoham Y, Shoham G (2004) Acta Crystallogr D Biol Crystallogr 60:836 Google Scholar
  88. 88.
    Andrade CM, Aguiar WB, Antranikian G (2001) Appl Biochem Biotechnol 91-93:655 CrossRefPubMedGoogle Scholar
  89. 89.
    Waino M, Ingvorsen K (2003) Extremophiles 7:87 PubMedGoogle Scholar
  90. 90.
    Linko M, Viikari L, Suihko ML (1984) Biotechnol Adv 2:233 CrossRefPubMedGoogle Scholar
  91. 91.
    Oksanen T, Pere J, Paavilainen L, Buchert J, Viikari L (2000) J Biotechnol 78:39 CrossRefPubMedGoogle Scholar
  92. 92.
    Schink B, Zeikus JB (1983) FEMS Microbiol Lett 17:295 CrossRefGoogle Scholar
  93. 93.
    Tamaru Y, Doi RH (2001) Proc Natl Acad Sci USA 98:4125 CrossRefPubMedGoogle Scholar
  94. 94.
    Van Rijssel M, Gerwig GJ, Hansen TA (1993) Appl Environ Microbiol 59:828 PubMedGoogle Scholar
  95. 95.
    Hoondal GS, Tiwari RP, Tewari R, Dahiya N, Beg QK (2002) Appl Microbiol Biotechnol 59:409 CrossRefPubMedGoogle Scholar
  96. 96.
    Kashyap DR, Vohra PK, Chopra S, Tewari R (2001) Bioresour Technol 77:215 CrossRefPubMedGoogle Scholar
  97. 97.
    Herron SR, Benen JA, Scavetta RD, Visser J, Jurnak F (2000) Proc Natl Acad Sci USA 97:8762 CrossRefPubMedGoogle Scholar
  98. 98.
    Prade RA, Zhan D, Ayoubi P, Mort AJ (1999) Biotechnol Genet Eng Rev 16:361 PubMedGoogle Scholar
  99. 99.
    Lang C, Dornenburg H (2000) Appl Microbiol Biotechnol 53:366 CrossRefPubMedGoogle Scholar
  100. 100.
    Sakai T, Sakamoto T, Hallaert J, Vandamme EJ (1993) Adv Appl Microbiol 39:213 PubMedGoogle Scholar
  101. 101.
    Rexova-Benkova L, Markovic O (1976) Adv Carbohydr Chem Biochem 33:323 PubMedGoogle Scholar
  102. 102.
    Kozianowski G, Canganella F, Rainey FA, Hippe H, Antranikian G (1997) Extremophiles 1:171 CrossRefPubMedGoogle Scholar
  103. 103.
    Kluskens LD, van Alebeek GJ, Voragen AG, de Vos WM, van der Oost J (2003) Biochem J 370:651 CrossRefPubMedGoogle Scholar
  104. 104.
    Cohen-Kupiec R, Chet I (1998) Curr Opin Biotechnol 9:270 CrossRefPubMedGoogle Scholar
  105. 105.
    Koga D, Mitsutomi M, Kono M, Matsumiya M (1999) EXS 87:111 PubMedGoogle Scholar
  106. 106.
    Fukamizo T (2000) Curr Protein Pept Sci 1:105 CrossRefPubMedGoogle Scholar
  107. 107.
    Takayanagi T, Ajisaka K, Takiguchi Y, Shimahara K (1991) Biochim Biophys Acta 1078:404 PubMedGoogle Scholar
  108. 108.
    Sakai K, Yokota A, Kurokawa H, Wakayama M, Moriguchi M (1998) Appl Environ Microbiol 64:3397 PubMedGoogle Scholar
  109. 109.
    Tsujibo H, Minoura K, Miyamoto K, Endo H, Moriwaki M, Inamori Y (1993) Appl Environ Microbiol 59:620 PubMedGoogle Scholar
  110. 110.
    Andronopoulou E, Vorgias CE (2004) Protein Expr Purif 35:264 CrossRefPubMedGoogle Scholar
  111. 111.
    Imanaka T, Fukui T, Fujiwara S (2001) Methods Enzymol 330:319 PubMedGoogle Scholar
  112. 112.
    Tanaka T, Fujiwara S, Nishikori S, Fukui T, Takagi M, Imanaka T (1999) Appl Environ Microbiol 65:5338 PubMedGoogle Scholar
  113. 113.
    Gao J, Bauer MW, Shockley KR, Pysz MA, Kelly RM (2003) Appl Environ Microbiol 69:3119 CrossRefPubMedGoogle Scholar
  114. 114.
    Grzybowska B, Szweda P, Synowiecki J (2004) Mol Biotechnol 26:101 CrossRefPubMedGoogle Scholar
  115. 115.
    Berk H, Lebbink RJ (2003) Methods Mol Biol 230:127 PubMedGoogle Scholar
  116. 116.
    Linden A, Mayans O, Meyer-Klaucke W, Antranikian G, Wilmanns M (2003) J Biol Chem 278:9875 CrossRefPubMedGoogle Scholar
  117. 117.
    Savchenko A, Vieille C, Kang S, Zeikus JG (2002) Biochemistry 41:6193 CrossRefPubMedGoogle Scholar
  118. 118.
    Savchenko A, Vieille C, Zeikus JG (2001) Methods Enzymol 330:354 PubMedGoogle Scholar
  119. 119.
    Leveque E, Haye B, Belarbi A (2000) FEMS Microbiol Lett 186:67 CrossRefPubMedGoogle Scholar
  120. 120.
    Canganella F, Gambacorta A, Kato C, Horikoshi K (2000) Microbiol Res 154:297 PubMedGoogle Scholar
  121. 121.
    Kato M, Miura Y, Kettoku M, Shindo K, Iwamatsu A, Kobayashi K (1996) Biosci Biotechnol Biochem 60:546 PubMedGoogle Scholar
  122. 122.
    Kobayashi K, Kato M, Miura Y, Kettoku M, Komeda T, Iwamatsu A (1996) Biosci Biotechnol Biochem 60:1720 PubMedGoogle Scholar
  123. 123.
    Haseltine C, Rolfsmeier M, Blum P (1996) J Bacteriol 178:945 PubMedGoogle Scholar
  124. 124.
    Lee J, Kanai H, Kobayashi T, Akiba T, Kudo T (1996) J Ferment Bioeng 82:432 CrossRefGoogle Scholar
  125. 125.
    Tachibana Y, Mendez L, Fujiwara S, Takagi M, Imanaka T (1996) J Ferment Bioeng 82:224 CrossRefGoogle Scholar
  126. 126.
    Liebl W, Stemplinger I, Ruile P (1997) J Bacteriol 179:941 PubMedGoogle Scholar
  127. 127.
    Horinouchi S, Fukusumi S, Ohshima T, Beppu T (1988) Eur J Biochem 176:243 CrossRefPubMedGoogle Scholar
  128. 128.
    Fukusumi S, Kamizono A, Horinouchi S, Beppu T (1988) Eur J Biochem 174:15 CrossRefPubMedGoogle Scholar
  129. 129.
    Ducki A, Grundmann O, Konermann L, Mayer F, Hoppert M (1998) J Gen Appl Microbiol 44:327 CrossRefPubMedGoogle Scholar
  130. 130.
    Ganghofner D, Kellermann J, Staudenbauer WL, Bronnenmeier K (1998) Biosci Biotechnol Biochem 62:302 CrossRefPubMedGoogle Scholar
  131. 131.
    Coutinho PM, Reilly PJ (1994) Protein Eng 7:749 PubMedGoogle Scholar
  132. 132.
    Coutinho PM, Reilly PJ (1994) Protein Eng 7:393 PubMedGoogle Scholar
  133. 133.
    Ohnishi H, Matsumoto H, Sakai H, Ohta T (1994) J Biol Chem 269:3503 PubMedGoogle Scholar
  134. 134.
    Ohnishi H, Kitamura H, Minowa T, Sakai H, Ohta T (1992) Eur J Biochem 207:413 CrossRefPubMedGoogle Scholar
  135. 135.
    Paquet V, Croux C, Goma G, Soucaille P (1991) Appl Environ Microbiol 57:212 PubMedGoogle Scholar
  136. 136.
    Glushchenko EV, Kozlov DG, Podkovyrov SM, Mogutov MA (1990) Mol Biol (Mosk) 24:744 Google Scholar
  137. 137.
    Kozlov DG, Kurepina NE, Glushchenko EV, Mogutov MA, Podkovyrov SM (1990) Mol Biol (Mosk) 24:736 Google Scholar
  138. 138.
    Saha BC, Mathupala SP, Zeikus JG (1988) Biochem J 252:343 PubMedGoogle Scholar
  139. 139.
    Hyun HH, Shen GJ, Zeikus JG (1985) J Bacteriol 164:1153 PubMedGoogle Scholar
  140. 140.
    Hyun HH, Zeikus JG (1985) J Bacteriol 164:1146 PubMedGoogle Scholar
  141. 141.
    Hyun HH, Zeikus JG (1985) J Bacteriol 164:1162 PubMedGoogle Scholar
  142. 142.
    Serour E, Antranikian G (2002) Antonie Van Leeuwenhoek 81:73 CrossRefGoogle Scholar
  143. 143.
    Kim MS, Park JT, Kim YW, Lee HS, Nyawira R, Shin HS, Park CS, Yoo SH, Kim YR, Moon TW, Park KH (2004) Appl Environ Microbiol 70:3933 CrossRefPubMedGoogle Scholar
  144. 144.
    Chang ST, Parker KN, Bauer MW, Kelly RM (2001) Methods Enzymol 330:260 PubMedGoogle Scholar
  145. 145.
    Galichet A, Belarbi A (1999) FEBS Lett 458:188 CrossRefPubMedGoogle Scholar
  146. 146.
    Xavier KB, Peist R, Kossmann M, Boos W, Santos H (1999) J Bacteriol 181:3358 PubMedGoogle Scholar
  147. 147.
    Schicho RN, Ma K, Adams MW, Kelly RM (1993) J Bacteriol 175:1823 PubMedGoogle Scholar
  148. 148.
    Costantino HR, Brown SH, Kelly RM (1990) J Bacteriol 172:3654 PubMedGoogle Scholar
  149. 149.
    Miura Y, Kettoku M, Kato M, Kobayashi K, Kondo K (1999) J Mol Microbiol Biotechnol 1:129 PubMedGoogle Scholar
  150. 150.
    Campbell BS, Siddique AB, McDougall BM, Seviour RJ (2004) FEMS Microbiol Lett 232:225 CrossRefPubMedGoogle Scholar
  151. 151.
    Bertoldo C, Antranikian G (2002) Curr Opin Chem Biol 6:151 CrossRefPubMedGoogle Scholar
  152. 152.
    Bertoldo C, Antranikian G (2001) Methods Enzymol 330:269 PubMedGoogle Scholar
  153. 153.
    Dong G, Vieille C, Zeikus JG (1997) Appl Environ Microbiol 63:3577 PubMedGoogle Scholar
  154. 154.
    Canganella F, Jones WJ, Gambacorta A, Antranikian G (1997) Arch Microbiol 167:233 CrossRefPubMedGoogle Scholar
  155. 155.
    Duffner F, Bertoldo C, Andersen JT, Wagner K, Antranikian G (2000) J Bacteriol 182:6331 CrossRefPubMedGoogle Scholar
  156. 156.
    Erra-Pujada M, Debeire P, Duchiron F, O'Donohue MJ (1999) J Bacteriol 181:3284 PubMedGoogle Scholar
  157. 157.
    Niehaus F, Peters A, Groudieva T, Antranikian G (2000) FEMS Microbiol Lett 190:223 CrossRefPubMedGoogle Scholar
  158. 158.
    Knapp S, Rudiger A, Antranikian G, Jorgensen PL, Ladenstein R (1995) Proteins 23:595 CrossRefPubMedGoogle Scholar
  159. 159.
    Rudiger A, Jorgensen PL, Antranikian G (1995) Appl Environ Microbiol 61:567 PubMedGoogle Scholar
  160. 160.
    Schwerdtfeger RM, Chiaraluce R, Consalvi V, Scandurra R, Antranikian G (1999) Eur J Biochem 264:479 CrossRefPubMedGoogle Scholar
  161. 161.
    Zona R, Chang-Pi-Hin F, O'Donohue MJ, Janecek S (2004) Eur J Biochem 271:2863 CrossRefPubMedGoogle Scholar
  162. 162.
    Kang S, Vieille C, Zeikus JG (2005) Appl Microbiol Biotechnol 66:408 CrossRefPubMedGoogle Scholar
  163. 163.
    Kim CH, Nashiru O, Ko JH (1996) FEMS Microbiol Lett 138:147 CrossRefPubMedGoogle Scholar
  164. 164.
    Bertoldo C, Duffner F, Jorgensen PL, Antranikian G (1999) Appl Environ Microbiol 65:2084 PubMedGoogle Scholar
  165. 165.
    Lebbink JH, Bertoldo C, Tibbelin G, Andersen JT, Duffner F, Antranikian G, Ladenstein R (2000) Acta Crystallogr D Biol Crystallogr 56 (Pt 11):1470 Google Scholar
  166. 166.
    Koch R, Canganella F, Hippe H, Jahnke K, Antranikian G (1997) Appl Environ Microbiol 63:1088 Google Scholar
  167. 167.
    Bibel M, Brettl C, Gosslar U, Kriegshauser G, Liebl W (1998) FEMS Microbiol Lett 158:9 CrossRefPubMedGoogle Scholar
  168. 168.
    Bertoldo C, Armbrecht M, Becker F, Schafer T, Antranikian G, Liebl W (2004) Appl Environ Microbiol 70:3407 CrossRefPubMedGoogle Scholar
  169. 169.
    Wind RD, Liebl W, Buitelaar RM, Penninga D, Spreinat A, Dijkhuizen L, Bahl H (1995) Appl Environ Microbiol 61:1257 PubMedGoogle Scholar
  170. 170.
    Knegtel RM, Wind RD, Rozeboom HJ, Kalk KH, Buitelaar RM, Dijkhuizen L, Dijkstra BW (1996) J Mol Biol 256:611 CrossRefPubMedGoogle Scholar
  171. 171.
    Tachibana Y, Kuramura A, Shirasaka N, Suzuki Y, Yamamoto T, Fujiwara S, Takagi M, Imanaka T (1999) Appl Environ Microbiol 65:1991 PubMedGoogle Scholar
  172. 172.
    Biwer A, Antranikian G, Heinzle E (2002) Appl Microbiol Biotechnol 59:609 CrossRefPubMedGoogle Scholar
  173. 173.
    Cowan DA, Smolenski KA, Daniel RM, Morgan HW (1987) Biochem J 247:121 PubMedGoogle Scholar
  174. 174.
    Guagliardi A, Cerchia L, Rossi M (2002) Biochem J 368:357 CrossRefPubMedGoogle Scholar
  175. 175.
    Burlini N, Magnani P, Villa A, Macchi F, Tortora P, Guerritore A (1992) Biochim Biophys Acta 1122:283 PubMedGoogle Scholar
  176. 176.
    Mayr J, Lupas A, Kellermann J, Eckerskorn C, Baumeister W, Peters J (1996) Curr Biol 6:739 CrossRefPubMedGoogle Scholar
  177. 177.
    Kannan Y, Koga Y, Inoue Y, Haruki M, Takagi M, Imanaka T, Morikawa M, Kanaya S (2001) Appl Environ Microbiol 67:2445 CrossRefPubMedGoogle Scholar
  178. 178.
    Morikawa M, Imanaka T (2001) Methods Enzymol 330:424 PubMedGoogle Scholar
  179. 179.
    Volkl P, Markiewicz P, Stetter KO, Miller JH (1994) Protein Sci 3:1329 PubMedGoogle Scholar
  180. 180.
    Chang LS, Hicks PM, Kelly RM (2001) Methods Enzymol 330:403 PubMedGoogle Scholar
  181. 181.
    Morikawa M, Izawa Y, Rashid N, Hoaki T, Imanaka T (1994) Appl Environ Microbiol 60:4559 PubMedGoogle Scholar
  182. 182.
    Klingeberg M, Galunsky B, Sjoholm C, Kasche V, Antranikian G (1995) Appl Environ Microbiol 61:3098 Google Scholar
  183. 183.
    Chavez Croocker P, Sako Y, Uchida A (1999) Extremophiles 3:3 CrossRefPubMedGoogle Scholar
  184. 184.
    Sako Y, Croocker PC, Ishida Y (1997) FEBS Lett 415:329 CrossRefPubMedGoogle Scholar
  185. 185.
    Catara G, Ruggiero G, La Cara F, Digilio FA, Capasso A, Rossi M (2003) Extremophiles 7:391 CrossRefPubMedGoogle Scholar
  186. 186.
    Voorhorst WG, Eggen RI, Geerling AC, Platteeuw C, Siezen RJ, Vos WM (1996) J Biol Chem 271:20 426 Google Scholar
  187. 187.
    de Vos WM, Voorhorst WG, Dijkgraaf M, Kluskens LD, Van der Oost J, Siezen RJ (2001) Methods Enzymol 330:383 Google Scholar
  188. 188.
    Voorhorst WG, Warner A, de Vos WM, Siezen RJ (1997) Protein Eng 10:905 CrossRefPubMedGoogle Scholar
  189. 189.
    Choi IG, Bang WG, Kim SH, Yu YG (1999) J Biol Chem 274:881 CrossRefPubMedGoogle Scholar
  190. 190.
    Lin X, Fusek M, Tang J (1991) Adv Exp Med Biol 306:255 PubMedGoogle Scholar
  191. 191.
    Fusek M, Lin XL, Tang J (1990) J Biol Chem 265:1496 PubMedGoogle Scholar
  192. 192.
    Lin X, Tang J (1990) J Biol Chem 265:1490 PubMedGoogle Scholar
  193. 193.
    Fujiwara S, Okuyama S, Imanaka T (1996) Gene 179:165 CrossRefPubMedGoogle Scholar
  194. 194.
    Friedrich A, Antranikian G (1996) Appl Environ Microbiol 62:2875 Google Scholar
  195. 195.
    Kim JS, Kluskens LD, de Vos WM, Huber R, van der Oost J (2004) J Mol Biol 335:787 CrossRefPubMedGoogle Scholar
  196. 196.
    Kluskens LD, Voorhorst WG, Siezen RJ, Schwerdtfeger RM, Antranikian G, van der Oost J, de Vos WM (2002) Extremophiles 6:185 CrossRefPubMedGoogle Scholar
  197. 197.
    Lesuisse E, Schanck K, Colson C (1993) Eur J Biochem 216:155 CrossRefPubMedGoogle Scholar
  198. 198.
    Sinchaikul S, Sookkheo B, Phutrakul S, Pan FM, Chen ST (2001) Protein Expr Purif 22:388 CrossRefPubMedGoogle Scholar
  199. 199.
    Cho AR, Yoo SK, Kim EJ (2000) FEMS Microbiol Lett 186:235 CrossRefPubMedGoogle Scholar
  200. 200.
    Lee D, Koh Y, Kim K, Kim B, Choi H, Kim D, Suhartono MT, Pyun Y (1999) FEMS Microbiol Lett 179:393 CrossRefPubMedGoogle Scholar
  201. 201.
    Tyndall JD, Sinchaikul S, Fothergill-Gilmore LA, Taylor P, Walkinshaw MD (2002) J Mol Biol 323:859 CrossRefPubMedGoogle Scholar
  202. 202.
    Crabb WD, Shetty JK (1999) Curr Opin Microbiol 2:252 CrossRefPubMedGoogle Scholar
  203. 203.
    Park BC, Koh S, Chang C, Suh SW, Lee DS, Byun SM (1997) Appl Biochem Biotechnol 62:15 PubMedGoogle Scholar
  204. 204.
    Liu SY, Wiegel J, Gherardini FC (1996) J Bacteriol 178:5938 PubMedGoogle Scholar
  205. 205.
    Vieille C, Hess JM, Kelly RM, Zeikus JG (1995) Appl Environ Microbiol 61:1867 PubMedGoogle Scholar
  206. 206.
    Vieille C, Sriprapundh D, Kelly RM, Zeikus JG (2001) Methods Enzymol 330:215 PubMedGoogle Scholar
  207. 207.
    Hess JM, Kelly RM (1999) Biotechnol Bioeng 62:509 CrossRefPubMedGoogle Scholar
  208. 208.
    Hess JM, Tchernajenko V, Vieille C, Zeikus JG, Kelly RM (1998) Appl Environ Microbiol 64:2357 PubMedGoogle Scholar
  209. 209.
    Cowan D (1996) Trends Biotech 14:177 CrossRefGoogle Scholar
  210. 210.
    Burdette DS, Vieille C, Zeikus JG (1996) Biochem J 316 (Pt 1):115 Google Scholar
  211. 211.
    Burdette DS, Jung SH, Shen GJ, Hollingsworth RI, Zeikus JG (2002) Appl Environ Microbiol 68:1914 CrossRefPubMedGoogle Scholar
  212. 212.
    Burdette DS, Tchernajencko VV, Zeikus JG (2000) Enzyme Microb Technol 27:11 CrossRefPubMedGoogle Scholar
  213. 213.
    Burdette DS, Secundo F, Phillips RS, Dong J, Scott RA, Zeikus JG (1997) Biochem J 326 (Pt 3):717 Google Scholar
  214. 214.
    Yoon SY, Noh HS, Kim EH, Kong KH (2002) Comp Biochem Physiol B Biochem Mol Biol 132:415 Google Scholar
  215. 215.
    Kong KH, Hong MP, Choi SS, Kim YT, Cho SH (2000) Biotechnol Appl Biochem 31 (Pt 2):113 Google Scholar
  216. 216.
    Abokitse K, Hummel W (2003) Appl Microbiol Biotechnol 62:380 CrossRefPubMedGoogle Scholar
  217. 217.
    Ma K, Adams MW (2001) Methods Enzymol 331:195 PubMedGoogle Scholar
  218. 218.
    Li D, Stevenson KJ (2001) Methods Enzymol 331:201 PubMedGoogle Scholar
  219. 219.
    Zhang J, Liu J, Zhou J, Ren Y, Dai X, Xiang H (2003) Biotechnol Lett 25:1463 CrossRefPubMedGoogle Scholar
  220. 220.
    Suzuki Y, Miyamoto K, Ohta H (2004) FEMS Microbiol Lett 236:97 CrossRefPubMedGoogle Scholar
  221. 221.
    Ikeda M, Clark DS (1998) Biotechnol Bioeng 57:624 CrossRefPubMedGoogle Scholar
  222. 222.
    Labahn J, Neumann S, Buldt G, Kula MR, Granzin J (2002) J Mol Biol 322:1053 CrossRefPubMedGoogle Scholar
  223. 223.
    Chebrou H, Bigey F, Arnaud A, Galzy P (1996) Biochim Biophys Acta 1298:285 PubMedGoogle Scholar
  224. 224.
    Kobayashi M, Komeda H, Nagasawa T, Nishiyama M, Horinouchi S, Beppu T, Yamada H, Shimizu S (1993) Eur J Biochem 217:327 CrossRefPubMedGoogle Scholar
  225. 225.
    Ciskanik l, Wilczek JM, Fallon RD (1995) Appl Environ Microbiol 61:998 Google Scholar
  226. 226.
    Trott S, Bauer R, Knackmuss HJ, Stolz A (2001) Microbiology 147:1815 PubMedGoogle Scholar
  227. 227.
    Mayaux J, Cerbelaud E, Soubrier F, Yeh P, Blanche F, Petre D (1991) J Bacteriol 173:6694 PubMedGoogle Scholar
  228. 228.
    Hirrlinger B, Stolz A, Knackmuss HJ (1996) J Bacteriol 178:3501 PubMedGoogle Scholar
  229. 229.
    Layh N, Hirrlinger B, Stolz A, Knackmuss HJ (1997) Appl Microbiol Biotechnol 47:668 CrossRefGoogle Scholar
  230. 230.
    Hermes H, Tandler RF, Sonke T, Dijkhuizen L, Meijer EM (1994) Appl Environ Microbiol 1:153 Google Scholar
  231. 231.
    Sonke T, Kaptein B, Boesten WHJ, Boxterman QB, Schoemaker HE, Kamphuis J, Formaggio F, Toniolo C, Rutjes FP (2000) In: RN P (ed) Stereoselective Biocatalysis. Marcel Dekker, New York p 23 Google Scholar
  232. 232.
    Kamphuis J, Boesten WHJ, Kaptein B, Hermes HFM, Sonke T, Broxterman QB, van den Tweel WJJ, Schoemaker HE (1992) in: Collins AN, Sheldrake GN, Crosby J (eds) Chirality in industry: the commercial manufacture and applications of optically active compounds. Wiley, Chichester, UK p 187 Google Scholar
  233. 233.
    Alcantara A-R, Sanchez-Montero JM, Sinisterra JV (2000) In: RN P (ed) Stereoselective biocatalysis. Marcel Dekker, New York p 659 Google Scholar
  234. 234.
    Webster N, Ramsden DK, Hughes J (2001) Biotechnol Lett 23:95 CrossRefGoogle Scholar
  235. 235.
    Fournand D, Arnaud A, Galzy P (1998) J Mol Catal 4:77 Google Scholar
  236. 236.
    Baek DH, Song JJ, Lee SG, Kwon SJ, Asano Y, Sung MH (2003) Enzyme Microb Technol 32:131 CrossRefGoogle Scholar
  237. 237.
    Nawaz M, Khan AA, Bhattacharayya D, Siitonen PH, Cerniglia CE (1996) J Bacteriol 178:2397 PubMedGoogle Scholar
  238. 238.
    d'Abusco AS, Ammendola S, Scandurra R, Politi L (2001) Extremophiles 5:183 CrossRefPubMedGoogle Scholar
  239. 239.
    Egorova K, Trauthwein H, Verseck S, Antranikian G (2004) Appl Microbiol Biotechnol 65:38 CrossRefPubMedGoogle Scholar
  240. 240.
    Mahadevan S, Thimann KV (1964) Arch Biochem Biophys 107:62 CrossRefPubMedGoogle Scholar
  241. 241.
    Thimann KV, Mahadevan S (1964) Arch Biochem Biophys 105:133 CrossRefPubMedGoogle Scholar
  242. 242.
    Hook RH, Robinson WG (1964) J Biol Chem 239:4263 PubMedGoogle Scholar
  243. 243.
    Robinson WG, Hook RH (1964) J Biol Chem 239:4257 PubMedGoogle Scholar
  244. 244.
    Arnaud A, Galzy P, Jallageas JC (1976) C R Acad Sci Hebd Seances Acad Sci D 283:571 PubMedGoogle Scholar
  245. 245.
    Harper DB (1977) Biochem J 167:685 PubMedGoogle Scholar
  246. 246.
    Harper DB (1977) Biochem J 165:309 PubMedGoogle Scholar
  247. 247.
    Wajant H, Effenberger F (2002) Eur J Biochem 269:680 CrossRefPubMedGoogle Scholar
  248. 248.
    Pekarsky Y, Campiglio M, Siprashvili Z, Druck T, Sedkov Y, Tillib S, Draganescu A, Wermuth P, Rothman JH, Huebner K, Buchberg AM, Mazo A, Brenner C, Croce CM (1998) Proc Natl Acad Sci USA 95:8744 CrossRefPubMedGoogle Scholar
  249. 249.
    Pace HC, Hodawadekar SC, Draganescu A, Huang J, Bieganowski P, Pekarsky Y, Croce CM, Brenner C (2000) Curr Biol 10:907 CrossRefPubMedGoogle Scholar
  250. 250.
    Harper DB (1985) Int J Biochem 17:677 CrossRefPubMedGoogle Scholar
  251. 251.
    Stevenson DE, Feng R, Dumas F, Groleau D, Mihoc A, Storer AC (1992) Biotechnol Appl Biochem 15:283 PubMedGoogle Scholar
  252. 252.
    Nagasawa T, Mauger J, Yamada H (1990) Eur J Biochem 194:765 CrossRefPubMedGoogle Scholar
  253. 253.
    Kobayashi M, Komeda H, Yanaka N, Nagasawa T, Yamada H (1992) J Biol Chem 267:20 746 Google Scholar
  254. 254.
    Kobayashi M, Yanaka N, Nagasawa T, Yamada H (1992) Biochemistry 31:9000 CrossRefPubMedGoogle Scholar
  255. 255.
    Banerjee A, Sharma R, Banerjee UC (2002) Appl Microbiol Biotechnol 60:33 CrossRefPubMedGoogle Scholar
  256. 256.
    Perler FB, Kumar S, Kong H (1996) Adv Protein Chem 48:377 PubMedGoogle Scholar
  257. 257.
    Mullis K, Faloona F, Scharf S, Saiki R, Horn G, Erlich H (1992) Biotechnology 24:17 PubMedGoogle Scholar
  258. 258.
    Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA (1988) Science 239:487 PubMedGoogle Scholar
  259. 259.
    Mullis K, Faloona F, Scharf S, Saiki R, Horn G, Erlich H (1986) Cold Spring Harb Symp Quant Biol 51 Pt 1:263 Google Scholar
  260. 260.
    Diaz RS, Sabino EC (1998) Braz J Med Biol Res 31:1239 CrossRefPubMedGoogle Scholar
  261. 261.
    Komori K, Ishino Y (2000) Protein Eng 13:41 CrossRefPubMedGoogle Scholar
  262. 262.
    Evans SJ, Fogg MJ, Mamone A, Davis M, Pearl LH, Connolly BA (2000) Nucleic Acids Res 28:1059 CrossRefPubMedGoogle Scholar
  263. 263.
    Hayashi I, Morikawa K, Ishino Y (1999) Nucleic Acids Res 27:4695 CrossRefPubMedGoogle Scholar
  264. 264.
    Goldman S, Kim R, Hung LW, Jancarik J, Kim SH (1998) Acta Crystallogr D Biol Crystallogr 54 (Pt 5):986 Google Scholar
  265. 265.
    Lu C, Erickson HP (1997) Protein Expr Purif 11:179 CrossRefPubMedGoogle Scholar
  266. 266.
    Uemori T, Sato Y, Kato I, Doi H, Ishino Y (1997) Genes Cells 2:499 CrossRefPubMedGoogle Scholar
  267. 267.
    Imamura M, Uemori T, Kato I, Ishino Y (1995) Biol Pharm Bull 18:1647 PubMedGoogle Scholar
  268. 268.
    Uemori T, Ishino Y, Toh H, Asada K, Kato I (1993) Nucleic Acids Res 21:259 PubMedGoogle Scholar
  269. 269.
    Ogata N, Miura T (2000) Biochemistry 39:13 993 CrossRefGoogle Scholar
  270. 270.
    Ogata N, Miura T (1998) Nucleic Acids Res 26:4652 CrossRefPubMedGoogle Scholar
  271. 271.
    Keohavong P, Ling L, Dias C, Thilly WG (1993) PCR Methods Appl 2:288 PubMedGoogle Scholar
  272. 272.
    Kong H, Kucera RB, Jack WE (1993) J Biol Chem 268:1965 PubMedGoogle Scholar
  273. 273.
    Mattila P, Korpela J, Tenkanen T, Pitkanen K (1991) Nucleic Acids Res 19:4967 PubMedGoogle Scholar
  274. 274.
    Cariello NF, Swenberg JA, Skopek TR (1991) Nucleic Acids Res 19:4193 PubMedGoogle Scholar
  275. 275.
    Hashimoto H, Nishioka M, Fujiwara S, Takagi M, Imanaka T, Inoue T, Kai Y (2001) J Mol Biol 306:469 CrossRefPubMedGoogle Scholar
  276. 276.
    Hashimoto H, Matsumoto T, Nishioka M, Yuasa T, Takeuchi S, Inoue T, Fujiwara S, Takagi M, Imanaka T, Kai Y (1999) J Biochem (Tokyo) 125:983 Google Scholar
  277. 277.
    Nishioka M, Fujiwara S, Takagi M, Imanaka T (1998) Nucleic Acids Res 26:4409 CrossRefPubMedGoogle Scholar
  278. 278.
    Takagi M, Nishioka M, Kakihara H, Kitabayashi M, Inoue H, Kawakami B, Oka M, Imanaka T (1997) Appl Environ Microbiol 63:4504 PubMedGoogle Scholar
  279. 279.
    Sanger F, Nicklen S, Coulson AR (1992) Biotechnology 24:104 PubMedGoogle Scholar
  280. 280.
    Bechtereva TA, Pavlov YI, Kramorov VI, Migunova B, Kiselev OI (1989) Nucleic Acids Res 17:10 507 Google Scholar
  281. 281.
    Rao VB, Saunders NB (1992) Gene 113:17 CrossRefPubMedGoogle Scholar
  282. 282.
    Vander Horn PB, Davis MC, Cunniff JJ, Ruan C, McArdle BF, Samols SB, Szasz J, Hu G, Hujer KM, Domke ST, Brummet SR, Moffett RB, Fuller CW (1997) Biotechniques 22:758 PubMedGoogle Scholar
  283. 283.
    Szybalski W (1990) Gene 90:177 CrossRefPubMedGoogle Scholar
  284. 284.
    Schalling M, Hudson TJ, Buetow KH, Housman DE (1993) Nat Genet 4:135 CrossRefPubMedGoogle Scholar
  285. 285.
    Landegren U, Schallmeiner E, Nilsson M, Fredriksson S, Baner J, Gullberg M, Jarvius J, Gustafsdottir S, Dahl F, Soderberg O, Ericsson O, Stenberg J (2004) J Mol Recognit 17:194 CrossRefPubMedGoogle Scholar
  286. 286.
    Georlette D, Blaise V, Bouillenne F, Damien B, Thorbjarnardottir SH, Depiereux E, Gerday C, Uversky VN, Feller G (2004) Biophys J 86:1089 PubMedGoogle Scholar
  287. 287.
    Housby JN, Southern EM (2002) Anal Biochem 302:88 CrossRefPubMedGoogle Scholar
  288. 288.
    Jonsson ZO, Thorbjarnardottir SH, Eggertsson G, Palsdottir A (1994) Gene 151:177 CrossRefPubMedGoogle Scholar
  289. 289.
    Thorbjarnardottir SH, Jonsson ZO, Andresson OS, Kristjansson JK, Eggertsson G, Palsdottir A (1995) Gene 161:1 CrossRefPubMedGoogle Scholar
  290. 290.
    Blondel T, Hjorleifsdottir SH, Fridjonsson OF, Aevarsson A, Skirnisdottir S, Hermannsdottir AG, Hreggvidsson GO, Smith AV, Kristjansson JK (2003) Nucleic Acid Res 31:7247 CrossRefPubMedGoogle Scholar
  291. 291.
    Kletzin A (1992) Nucleic Acid Res 20:5389 PubMedGoogle Scholar
  292. 292.
    Nakatani M, Ezaki S, Atomi H, Imanaka T (2002) Eur J Biochem 269:650 CrossRefPubMedGoogle Scholar
  293. 293.
    Rolland JL, Guenguen Y, Persillon C, Masson JM, Dietrich J (2004) FEMS Microbiol Lett 236:267 CrossRefPubMedGoogle Scholar

Authors and Affiliations

  • Garabed Antranikian
    • 1
  • Constantinos E. Vorgias
    • 2
  • Costanzo Bertoldo
    • 1
  1. 1.Institute of Technical MicrobiologyTechnical University Hamburg-HarburgHamburgGermany
  2. 2.Faculty of Biology, Department of Biochemistry and Molecular BiologyNational and Kapodistrian University of AthensAthensGreece

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