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Novel Insights on the Functional Aspects of Quorum Sensing Systems and Its Applications in Medicine, Food Industry, and Agriculture

  • Pallaval Veera BramhachariEmail author
Chapter

Abstract

Microbes accustom to an array of behaviors and coordinate population signaled by AHL molecules to determine population density, trigger new patterns of gene expression, and mount virulence and pathogenesis. Diverse bacterial behaviors regulated by quorum sensing systems have a noteworthy impact on different fields of medicine, industry, and agriculture. Therefore, the ability of AHL molecules to modulate QS systems has remarkable real-world implications. This book exemplifies the magnitude and applications of QS and quorum sensing inhibitors (QSI) and its critical role in regulating diverse cellular functions. QS regulates interactions in both signal-producing organisms and between different species, viz., pathogenic, beneficial, and symbiotic microbes and higher organisms (symbiosis, growth promotion, pathogenicity). Its importance in agriculture (in the areas of plant–microbe interactions in connection to symbiosis and pathogenicity (plant growth promotion, biocontrol, virulence, and pathogenesis) ecology (microbial habitats), medicine (colonization of medical devices and disease causing human and animal hosts), food industry (food production, spoilage, and preservation), aquatic, industrial plant biofouling and activated sludge digestion. Nonetheless, complete management of bacterial quorum circuit in a biotechnological application is yet to be an incredulous goal. These strategies that are only in a preface and pose quite a lot of questions on exact nature of biofilms both in terms of implicated microbes and composition of extracellular matrix will remain a great task, but unquestionably this field stands high hope for future applications.

Keywords

Acyl homoserine lactones (AHL) Quorum sensing (QS) Quorum sensing inhibitors (QSI) Biofilm formation Medicine Agriculture Food industry 

Notes

Acknowledgments

Dr.Bramhachari is grateful to Krishna University for extending the necessary support.

Conflict of Interest

The author declare that there is no conflict of interest.

References

  1. Bai AJ, Rai VR (2011) Bacterial quorum sensing and food industry. Compr Rev Food Sci Food Saf 10(3):183–193CrossRefGoogle Scholar
  2. Bai AJ, Vittal RR (2014a) Quorum sensing inhibitory and anti-biofilm activity of essential oils and their in vivo efficacy in food systems. Food Biotechnol 28:269–292CrossRefGoogle Scholar
  3. Bai AJ, Vittal RR (2014b) Quorum sensing inhibitory and anti-biofilm activity of essential oils and their in vivo efficacy in food systems. Food Biotechnol 28:269–292CrossRefGoogle Scholar
  4. Bramhachari PV (2018) Introduction to quorum sensing research in diverse microbial systems. In: Implication of quorum sensing system in biofilm formation and virulence. Springer, Singapore, pp 3–6CrossRefGoogle Scholar
  5. Bramhachari PV (ed) (2019) Implication of quorum sensing system in biofilm formation and virulence. Springer, ChamGoogle Scholar
  6. Brooks JD, Flint SH (2008a) Biofilms in the food industry: problems and potential solutions. Int J Food Sci Technol 43:2163–2176CrossRefGoogle Scholar
  7. Brooks JD, Flint SH (2008b) Biofilms in the food industry: problems and potential solutions. Int J Food Sci Technol 43:2163–2176CrossRefGoogle Scholar
  8. Cao HJ et al (2009) Complex quorum-sensing regulatory systems regulate bacterial growth and symbiotic nodulation in Mesorhizobium tianshanense. Arch Microbiol 191:283–289CrossRefGoogle Scholar
  9. De Kievit TR (2009) Quorum sensing in Pseudomonas aeruginosa biofilms. Environ Microbiol 11(2):279–288Google Scholar
  10. Defoirdt T, Boon N, Bossier P, Verstraete W (2004) Disruption of bacterial quorum sensing: an unexplored strategy to fight infections in aquaculture. Aquaculture 240:69–88CrossRefGoogle Scholar
  11. Flemming H-C, Wingender J, Szewzyk U, Steinberg P, Rice SA, Kjelleberg S (2016) Biofilms: an emergent form of bacterial life. Nat Rev Microbiol 14:563–575CrossRefGoogle Scholar
  12. Galiè S, García-Gutiérrez C, Miguélez EM, Villar CJ, Lombó F (2018) Biofilms in the food industry: health aspects and control methods. Front Microbiol 9:898CrossRefGoogle Scholar
  13. Gopal N, Hill C, Ross PR, Beresford TP, Fenelon MA, Cotter PD (2015) The prevalence and control of Bacillus and related spore-forming bacteria in the dairy industry. Front Microbiol 6:1418CrossRefGoogle Scholar
  14. Huang J, Yang Y, Zeng G, Gu Y, Shi Y, Yi K et al (2019) Membrane layers intensifying quorum quenching alginate cores and its potential for membrane biofouling control. Bioresour Technol 279:195–201CrossRefGoogle Scholar
  15. Köhler T, Buckling A, Van Delden C (2009) Cooperation and virulence of clinical Pseudomonas aeruginosa populations. Proc Natl Acad Sci 106(15):6339–6344CrossRefGoogle Scholar
  16. Kothari V, Patel P, Joshi C (2018) Modulation of microbial quorum sensing: Nanotechnological approaches. In: Design of nanostructures for versatile therapeutic applications. William Andrew Publishing, Oxford, pp 523–563CrossRefGoogle Scholar
  17. Mangwani N, Dash HR, Chauhan A, Das S (2012) Bacterial quorum sensing: functional features and potential applications in biotechnology. J Mol Microbiol Biotechnol 22(4):215–227CrossRefGoogle Scholar
  18. Sanchez-Contreras M et al (2007) Quorum-sensing regulation in rhizobia and its role in symbiotic interactions with legumes. Philos Trans R Soc B Biol Sci 362:1149–1163CrossRefGoogle Scholar
  19. Shrout JD, Chopp DL, Just CL, Hentzer M, Givskov M, Parsek MR (2006) The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol Microbiol 62(5):1264–1277CrossRefGoogle Scholar
  20. von Bodman SB, Willey JM, Diggle SP (2008) Cell-cell communication in bacteria: united we stand. J Bacteriol 190(13):4377–4391CrossRefGoogle Scholar
  21. Wang ZW, Chen S (2009) Potential of biofilm-based biofuel production. Appl Microbiol Biotechnol 83(1):1–18CrossRefGoogle Scholar
  22. Waters CM, Bassler BL (2005) Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol 21:319–346CrossRefGoogle Scholar
  23. Welch M et al (2005) Cell–cell communication in Gram-negative bacteria. Mol BioSyst 1:196–202CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of BiotechnologyKrishna UniversityMachilipatnamIndia

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