Nervous System Disorders in Chronic Kidney Disease: Neurocognitive Dysfunction, Depression, and Sleep Disorder

  • Wenjin LiuEmail author


Nervous system disorders, including cognitive impairment, depression, and sleep disorder, are highly prevalent in patients with chronic kidney disease (CKD). The mechanisms leading to the increased prevalence are usually multifaceted. These complications can pose great threat to patients’ health and quality of life, but sometimes could be neglected or unrealized in clinical practice. Therefore, physicians should be aware of the features of these conditions in CKD patients and need to consider performing routine screening tests, especially in those with advanced renal dysfunction. Management of these complications usually requires identification and targeted treatment of reversible underlying causes, general supporting management of CKD, and consultation with specialist in relevant areas.


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© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Centre for Kidney DiseaseSecond Affiliated Hospital, Nanjing Medical UniversityNanjingChina

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