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Chromogenic Platform-Based Lateral Flow Immunoassay

  • Na Liu
  • Aibo WuEmail author
Chapter

Abstract

In general, several instrumental analytical methods (i.e., TLC, HPLC, CE-MS, LC-MS, MS-MS) of chromatography and rapid detection approaches of ELISA and FLA formats have been widely developed and proved to be sensitive and reliable for diverse occasions and purposes. In the recent decade, there is a still increasing interest in developing new strategic platforms which are simple, portable, disposable, and inexpensive, enabling to rapidly and simultaneously detect the target analytes in the fields of clinical diagnosis, environmental monitoring, and food safety control. Especially, those expected detection formats are extremely useful and highly welcome in remote settings, with high specificity and affinity to the target molecules showing more prospective to fulfill the above objective for these typed rapid analysis, which had been proved to be applicable for detecting clinical diseases and for monitoring environmental and food-based mycotoxins. We here propose some schematic immunoassay via a chromogenic platform-based FLA, attaining to the abovementioned expectations regarding developing ideal rapid tests of mycotoxins, especially for large-scale monitoring for industrial uses.

Keywords

Mycotoxin Rapid detection Immunoassay Lateral flow assay Chromogenic quantitation 

References

  1. Cavaliere C, Foglia P, Pastorini E, Samperi R, Lagana A (2005) Development of a multiresidue method for analysis of major Fusarium mycotoxins in corn meal using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 19(14):2085–2093CrossRefGoogle Scholar
  2. Feng L, Wang X, Jin H (2011) Rabbit monoclonal antibody: potential application in cancer therapy. Am J Transl Res 3(3):269PubMedPubMedCentralGoogle Scholar
  3. Friguet B, Chaffotte AF, Djavadi-Ohaniance L, Goldberg ME (1985) Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J Immunol Methods 77(2):305–319CrossRefGoogle Scholar
  4. Kinani S, Bouchonnet S, Bourcier S, Porcher JM, Ait-Aissa S (2008) Study of the chemical derivatization of zearalenone and its metabolites for gas chromatography-mass spectrometry analysis of environmental samples. J Chromatogr A 1190(1–2):307–315CrossRefGoogle Scholar
  5. Kolosova AY, De Saeger S, Sibanda L, Verheijen R, Van Peteghem C (2007) Development of a colloidal gold-based lateral-flow immunoassay for the rapid simultaneous detection of zearalenone and deoxynivalenol. Anal Bioanal Chem 389(7–8):2103–2107CrossRefGoogle Scholar
  6. Kolosova AY, Sibanda L, Dumoulin F, Lewis J, Duveiller E, Van Peteghem C, De Saeger S (2008) Lateral-flow colloidal gold-based immunoassay for the rapid detection of deoxynivalenol with two indicator ranges. Anal Chim Acta 616(2):235–244CrossRefGoogle Scholar
  7. Lai W, Fung DYC, Yang X, Renrong L, Xiong Y (2009) Development of a colloidal gold strip for rapid detection of ochratoxin A with mimotope peptide. Food Control 20(9):791–795CrossRefGoogle Scholar
  8. Laura A, Gilda DA, Claudio B, Cristina G, Gianfranco G (2011) A lateral flow immunoassay for measuring ochratoxin A: development of a single system for maize, wheat and durum wheat. Food Control 22(12):1965–1970CrossRefGoogle Scholar
  9. Li Y-S, Zhou Y, Lu S-Y, Guo D-J, Ren H-L, Meng X-M, Zhi B-H, Lin C, Wang Z, Li X-B, Liu Z-S (2012) Development of a one-step test strip for rapid screening of fumonisins B1, B2 and B3 in maize. Food Control 24(1–2):72–77CrossRefGoogle Scholar
  10. Liu G, Han Z, Nie D, Yang J, Zhao Z, Zhang J, Li H, Liao Y, Song S, De Saeger S, Wu A (2012) Rapid and sensitive quantitation of zearalenone in food and feed by lateral flow immunoassay. Food Control 27(1):200–205.  https://doi.org/10.1016/j.foodcont.2012.03.023CrossRefGoogle Scholar
  11. Liu N, Zhao Z, Tan Y, Lu L, Wang L, Liao Y, Beloglazova N, De Saeger S, Zheng X, Wu A (2016) Simultaneous raising of rabbit monoclonal antibodies to fluoroquinolones with diverse recognition functionalities via single mixture immunization. Anal Chem 88(2):1246–1252.  https://doi.org/10.1021/acs.analchem.5b03637CrossRefPubMedGoogle Scholar
  12. Molinelli A, Grossalber K, Führer M, Baumgartner S, Sulyok M, Krska R (2008) Development of qualitative and semiquantitative immunoassay-based rapid strip tests for the detection of T-2 toxin in wheat and oat. J Agric Food Chem 56(8):2589–2594.  https://doi.org/10.1021/jf800393jCrossRefPubMedGoogle Scholar
  13. Rocha R, Nunes C, Rocha G, Oliveira F, Sanches F, Gobbi H (2008) Rabbit monoclonal antibodies show higher sensitivity than mouse monoclonals for estrogen and progesterone receptor evaluation in breast cancer by immunohistochemistry. Pathol Res Pract 204(9):655–662.  https://doi.org/10.1016/j.prp.2008.03.010CrossRefPubMedGoogle Scholar
  14. Smits HL, Eapen CK, Sugathan S, Kuriakose M, Gasem MH, Yersin C, Sasaki D, Pujianto B, Vestering M, Abdoel TH, Gussenhoven GC (2001) Lateral-flow assay for rapid serodiagnosis of human leptospirosis. Clin Diagn Lab Immunol 8(1):166–169.  https://doi.org/10.1128/cdli.8.1.166-169.2001CrossRefPubMedPubMedCentralGoogle Scholar
  15. Song S, Liu N, Zhao Z, Njumbe Ediage E, Wu S, Sun C, De Saeger S, Wu A (2014) Multiplex lateral flow immunoassay for mycotoxin determination. Anal Chem 86(10):4995–5001.  https://doi.org/10.1021/ac500540zCrossRefPubMedGoogle Scholar
  16. Spieker-Polet H, Sethupathi P, Yam PC, Knight KL (1995) Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas. Proc Natl Acad Sci 92(20):9348–9352CrossRefGoogle Scholar
  17. Swanson SP, Corley RA, White DG, Buck WB (1984) Rapid thin layer chromatographic method for determination of zearalenone and zearalenol in grains and animal feeds. J Assoc Off Anal Chem 67(3):580–582PubMedGoogle Scholar
  18. Tanaka T, Hasegawa A, Matsuki Y, Lee U-S, Ueno Y (1985) Rapid and sensitive determination of zearalenone in cereals by high-performance liquid chromatography with fluorescence detection. J Chromatogr A 328(0):271–278CrossRefGoogle Scholar
  19. Tang D, Sauceda JC, Lin Z, Ott S, Basova E, Goryacheva I, Biselli S, Lin J, Niessner R, Knopp D (2009) Magnetic nanogold microspheres-based lateral-flow immunodipstick for rapid detection of aflatoxin B2 in food. Biosens Bioelectron 25(2):514–518CrossRefGoogle Scholar
  20. Xu Y, Huang Z-B, He Q-H, Deng S-Z, Li L-S, Li Y-P (2010) Development of an immunochromatographic strip test for the rapid detection of deoxynivalenol in wheat and maize. Food Chem 119(2):834–839CrossRefGoogle Scholar
  21. Yu Y, Lee P, Ke Y, Zhang Y, Yu Q, Lee J, Li M, Song J, Chen J, Dai J (2010) A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models. PLoS One 5(2):e9072CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological SciencesUniversity of Chinese Academy of Sciences, Chinese Academy of SciencesShanghaiPeople’s Republic of China

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