Abstract
The IoT revolution reshapes contemporary healthcare systems by incorporate economic, social, and technological prospects. It is progressing from conventional healthcare systems to more personalized healthcare systems, where patients can be monitored, diagnosed and treated effortlessly. Radiomics is a sub-field of machine learning (ML) that mines quantitative features from radiological images relying on an image-based approach with ML models, which procure information surpassing orthodox medical imaging analysis as diagnosis, prognosis, prediction and response to therapy. The upsurge in the number of radiological images increases the workload of radiologist which in turns decreases their performance, thus they can only detect and evaluate a small portion of information present in images within a short-time. Hence, there is need for a better method for the increase in radiological image selection, detection and evaluation processes thereby reducing the workload of experts. Therefore, this chapter discusses the different types and sources of radiological data, feature extraction and selection method for image analysis. The chapter also presents different ML models ideal for the radiomics and parameter tuning. The challenges, applicability and limitations of Radiomics are also described in this chapter. The radiomic process involves radiological image gathering, segmentation, feature extraction and selection, model building and evaluation. Each of the stage of the process workflow is carefully evaluated for development of a reliable, effective and robust model to be shifted into medical practice for disease diagnosis and prognosis response to treatment.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
van Griethuysen, J. J. M., Fedorov, A., Parmar, C., Hosny, A., Aucoin, N., Narayan, V., Beets-Tan, R. G. H., Fillion-Robin, J.-C., Pieper, S., & Aerts, H. J. W. L. (2017). Computational radiomics system to decode the radiographic phenotype. Cancer Research, 77(21), e104–e107.
Lambin, P., Rios-Velazquez, E., Leijenaar, R., Carvalho, S., van Stiphout, R. G. P. M., Granton, P., Zegers, C. M. L., Gillies, R., Boellard, R., Dekker, A., & Aerts, H. J. W. L. (2012). Radiomics: Extracting more information from medical images using advanced feature analysis. European Journal of Cancer, 48, 441–446.
Gillies, R. J., Kinahan, P. E., & Hricak, H. (2016). Radiomics: Images are more than pictures, they are data. Radiology, 278(2), 563–577.
Akmandor, O. A., & Jha, N. K. (2017). Smart health care: An edge-side computing perspective. IEEE Consumer Electronics Magazine, 7(1), 29–37.
Greco, L., Percannella, G., Ritrovato, P., Tortorella, F., & Vento, M. (2020). Trends in IoT based solutions for health care: Moving AI to the edge. Pattern Recognition Letters, 135, 346–353.
Chen, P.-H., & Cross, N. (2018). IoT in radiology: Using Raspberry Pi to automatically log telephone calls in the reading room. Journal of Digital Imaging, 31, 371–378.
Gil, D., Ferrández, A., Mora-Mora, H., & Peral, J. (2016). Internet of Things: A review of surveys based on context aware intelligent services. Sensors, 16.
Upton, E. (2016). Ten Millionth raspberry pi, and a new kit. Raspberry Pi. [Online].
Mahdavinejad, M. S., Rezvan, M., Barekatain, M., Adibi, P., Barnaghi, P., & Sheth, A. P. (2018). Machine learning for internet of things data analysis: A survey. Digital Communications and Networks, 4, 161–175.
Qin, Y., Sheng, Q. Z., Falkner, N. J., Dustdar, S., Wang, H., & Vasilakos, A. V. (2016). When things matter: A survey on data-centric internet of things. Journal of Network and Computer Applications, 64, 137–153.
Sheng, Z., Yang, S., Yu, Y., Vasilakos, A. V., McCann, J. A., & Leung, K. K. (2013) A survey on the IETF protocol suite for the Internet of Things: Standards, challenges and opportunities. IEEE Wireless Communications, 20(6), 91–98.
Yadav, A., Kumar Singh, V., Kumar Bhoi, A., Marques, G., Garcia-Zapirain, B., & de la Torre Díez, I. (2020). Wireless body area networks: UWB wearable textile antenna for telemedicine and mobile health systems. Micromachines, 11(6), 558.
Marques, G., Bhoi, A. K., de Albuquerque, V. H. C., K.S., H. (Eds.), (2021). IoT in healthcare and ambient assisted living. Springer.
Marques, G., Miranda, N., Kumar Bhoi, A., Garcia-Zapirain, B., Hamrioui, S., & de la Torre Díez, I. (2020). Internet of Things and enhanced living environments: Measuring and mapping air quality using cyber-physical systems and mobile computing technologies. Sensors, 20(3), 720.
Oniani, S., Marques, G., Barnovi, S., Pires, I. M., & Bhoi, A. K. (2020). Artificial intelligence for internet of things and enhanced medical systems. In Bio-inspired neurocomputing (pp. 43–59). Springer.
Chandy, A. (2019). A review on IoT based medical imaging technology for healthcare applications. Journal of Innovative Image Processing (JIIP), 1(1), 51–60.
Lambin, P., Leijenaar, R. T. H., Deist, T. M., Peerlings, J., de Jong, E. E. C., van Timmeren, J., Sanduleanu, S., Larue, R. T. H. M., Even, A. J. G., Jochems, A., van Wijk, Y., Woodruff, H., van Soest, J., Lustberg, T., Roelofs, E., van Elmpt, W., Dekker, A., Mottaghy, F. M., Wildberger, J. E., & Walsh, S. (2017) Radiomics: The bridge between medical imaging and personalized medicine. Nature Reviews Clinical Oncology, 17, 749–762.
Bizzego, A., Bussola, N., Salvalai, D., Chierici, M., Maggio, V., Jurmany, G., & Furlanello, C. (2016) Integrating deep and radiomics features in cancer bioimaging.
Court, L. E., Fave, X., Mackin, D., Lee, J., Yang, J., & Zhang, L. (2016). Computational resources for radiomics. Translational Cancer Research, 5, 340–348.
Balagurunathan, Y., Gu, Y., Wang, H., Kumar, V., Grove, O., Hawkins, S., Kim, J., Goldgof, D. B., Hall, L. O., Gatenby, R. A., & Gillies, R. J. (2014). Reproducibility and prognosis of quantitative features extracted from CT images. Translational Oncology, 7(1), 72–87.
Hui, G., & Oksam, C. (2010). Individual tooth segmentation from CT images using level set method with shape and intensity prior. Pattern Recognition, 43(7), 2406–2417.
Ye, X., Beddoe, G., & Slabaugh, G. (2010). Automatic graph cut segmentation of lesions in CT using mean shift superpixels. International Journal of Biomedical Imaging, 983963.
Chen, X., Udupa, J. K., Bagci, U., Zhuge, Y., & Yao, J. (2012). Medical image segmentation by combining graph cuts and oriented active appearance models. IEEE Transactions on Image Processing, 21(4), 2035–2046.
Suzuki, K., Kohlbrenner, R., Epstein, M. L., Obajuluwa, A. M., Xu, J., & Hori, M. (2010). Computer-aided measurement of liver volumes in CT by means of geodesic active contour segmentation coupled with level-set algorithms. Medical Physics, 37(5), 2159–2166.
Zhou, M., Scott, J., Chaudhury, B., Hall, J., Goldgof, D., Yeom, K. W., Ou, I. M. Y., Kalpathy-Cramer, J., Napel, S., Gillies, R., Gevaert, O., & Gatenby, R. (2018). Radiomics in brain tumor: Image assessment, quantitative feature descriptors, and machine-learning approaches. American Journal of Neuroradiology, 39(2), 208–216.
Dalal, N., & Triggs, B. (2005). Histograms of oriented gradients for human detection. In Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR ‘05), San Diego, Calif, USA, June 2005.
Ojala, T., Pietikäinen, M., & Harwood, D. (1994). Performance evaluation of texture measures with classification based on Kullback discrimination of distributions. In Proceedings of the 12th IAPR International Conference on Pattern Recognition (ICPR 1994).
Nanni, I., Lumini, A., & Brahnam, S. (2010). Local binary patterns variants as texture descriptors for medical image analysis. Artificial Intelligence in Medicine, 49(2), 117–125.
Khoshgoftaar, T., Dittman, D., Wald, R., & Fazelpour, A. (2013). First order statistics based feature selection: A diverse and powerful family of feature seleciton techniques. In Proceedings of 11th International Conference on Machine Learning and Applications, Boca Raton, FL, Boca Raton, Florida.
Rivera, A. R., Castillo, J. R., & Chae, O. O. (2013). Local directional number pattern for face analysis: Face and expression recognition. IEEE Transactions on Image Processing, 22(5), 1740–1752.
Song, T., Li, H., Meng, F., Wu, Q., & Cai, J. (2018). LETRIST: Locally encoded transform feature histogram for rotation-invariant texture classification. IEEE Transactions on Circuits and Systems for Video Technology, 28(7), 1565–1579.
Kannala, J., & Rahtu, E. (2012). BSIF: Binarized statistical image features. In Proceedings of the 21st International Conference on Pattern Recognition (ICPR2012), Tsukuba.
Belahcene, M., Laid, M., Chouchane, A., Ouamane, A., & Bourennane, S. (2016). Local descriptors and tensor local preserving projections in face recognition. In Proceedings of the 6th European Workshop at the Visual Information Processing (EUVIP), Marseille, France.
Lillholm, M., & Griffin, L. (2008). Novel image feature alphabets for object recognition. In 19th International Conference on Pattern Recognition (ICPR 2008), Tampa, Florida, USA.
Simonyan, K., & Zisserman, A. (2015). Very deep convolutional networks for large-scale image recognition. In International Conference on Learning Representations (ICLR).
He, K., Zhang, X., Ren, S., & Sun, J. (2016). Deep residual learning for image recognition. In Proceedings of IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Las Vegas, NV.
Szegedy, C., Vanhoucke, V., Ioffe, S., Shlens, J., & Wojna, Z. (2016). Rethinking the inception architecture for computer vision. In Proceedings of IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Las Vegas, NV.
Sandler, M., Howard, A., Zhu, M., Zhmoginov, A., & Chen, L. (2018). MobileNetV2: Inverted residuals and linear bottlenecks. In Proceedings of IEEE/CVF Conference on Computer Vision and Pattern Recognition, Salt Lake City, UT.
Huang, G., Liu, Z., Van Der Maaten, L., & Weinberger, K. Q. (2017). Densely connected convolutional networks. In Proceeding IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Honolulu, HI.
Tan, M., & Le, Q. V. (2019). EfficientNet: Rethinking model scaling for convolutional neural networks. In Proceedings of the 36th International Conference on Machine Learning (ICML 2019), Long Beach, California.
Zoph, B., Vasudevan, V., Shlens, J., & Le, Q. V. (2018). Learning transferable architectures for scalable image recognition. In Proceedings IEEE/CVF Conference on Computer Vision and Pattern Recognition, Salt Lake City, UT.
Huynh, B., Li, H., & Giger, M. L. (2016). Digital mammographic tumor classification using transfer learning from deep convolutional neural networks. Journal of Medical Imaging (Bellingham), 2(3), 034501.
Hotelling, H. (1933). Analysis of a complex of statistical variables into principal components. Journal of Educational Psychology, 24(6), 417.
Gil, D., Díaz-Chito, K., Sánchez, C., & Hernández-Sabaté, A. (2020). Early screening of SARS-CoV-2 by intelligent analysis of X-ray images. arXiv preprint arXiv:2005.13928.
Motwani, M., Dey, D., Berman, D. S., Germano, G., Achenbach. S., Al-Mallah. M. H., Chang, H. J., et al. (2017). Machine learning for prediction of all-cause mortality in patients with suspected coronary artery disease: A 5-year multicentre prospective registry analysis. European Heart Journal, 38(7), 500–507.
Agrawal, R. K., Kaur, B., & Sharma, S. (2020). Quantum based whale optimization al-gorithm for wrapper feature selection. Applied Soft Computing, 89(106092).
Wiharto, W., Suryani, E., & Cahyawati, V. (2019). The methods of duo output neural network ensemble for the prediction of coronary heart disease. Indonesian Journal of Electrical Engineering and Informatics (IJEEI), 7(1), 51–58.
Nilashi, M., Bin Ibrahim, O., Ahmadi, H., & Shahmoradi, L. (2017). An analytical method for diseases prediction using machine learning techniques. Computers and Chemical Engineering, 106, 212–223.
Liu, H., & Lang, B. (2019). Machine learning and deep learning methods for intrusion detection systems: A survey. Applied Sciences, 9(4396), 1–28.
Lundberg, S. M., & Lee, S. I. (2017). A unified approach to interpreting model predictions. In Proceedings of the Annual Processing Systems, Long Beach, CA, USA.
Ordóñez, P. F., Cepeda, C. M., Garrido, J., & Chakravarty, S. (2017). Classification of images based on small local features: A case applied to microaneurysms in fundus retina images. Journal of Medical Imaging, 4(4), 041309.
Shafiee, M. J., Chung, A. G., Khalvati, F., Haider, M. A., & Wong, A. (2017). Discovery radiomics via evolutionary deep radiomic sequencer discovery for pathologically proven lung cancer detection. Journal of Medical Imaging, 4(4), 041305.
Vaidhya, K., Thirunavukkarasu, S., Alex, V., & Krishnamurthi, G. (2016). Multi-modal Brain Tumor Segmentation Using Stacked Denoising Autoencoders. In Brainlesion: Glioma, Multiple Sclerosis, Stroke and TMultiple Sclerosis, Stroke and Traumatic Brain Injuries. (BrainLes 2015). Lecture notes in computer science.
Alex, K. V., Thirunavukkarasu, S., Kesavadas, C., & Krishnamurthi, G. (2017). Semisupervised learning using denoising autoencoders for brain lesion detection and segmentation. Journal of Medical Imaging (Bellingham), 4(4), 041311.
Li, H., Giger, M. L., Huynh, B. Q., & Antropova, N. O. (2017). Deep learning in breast cancer risk assessment: evaluation of convolutional neural networks on a clinical dataset of full-field digital mammograms. Journal of Medical Imaging (Bellingham), 4(4), 041304.
Liu, S., Xie, Y., Jirapatnakul, A., & Reevesa, A. P. (2017). Pulmonary nodule classification in lung cancer screening with three-dimensional convolutional neural networks. Journal of Medical Imaging (Bellingham), 4(4), 041308.
Shahedi, M., Cool, D. W., Bauman, G. S., Bastian-Jordan, M., Fenster, A., & Ward, A. D. (2017). Accuracy validation of an automated method for prostate segmentation in magnetic resonance imaging. Journal of Digit Imaging, 30, 782–795.
Cheng, R., Turkbey, B., Gandler. W., Agarwal, H. K., Shah, V. P., Bokinsky, A., McCreedy, E., Wang. S., Sankineni, S., Bernardo. M., Pohida. T., Choyke, P., & McAuliffe, M. J. (2014). Atlas based AAM and SVM model for fully automatic MRI prostate segmentation. In Conference Proceedings of IEEE Engineering Medical Biology Society (pp. 2881–2885).
Runkler, T. A. (2016). Data analytics: Models and algorithms for intelligent data analysis (2nd ed., p. 158). Springer Vieweg.
Folorunso, S. O., & Adeyemo, A. B. (2013). Alleviating classification problem of imbalanced dataset. African Journal of Computing and ICT, 6(1), 137–144.
Afshar, P., Mohammadi, A., Plataniotis, K. N., Oikonomou, A., & Benali, H. (2019). From handcrafted to deep-learning-based cancer radiomics: Challenges and opportunities. IEEE Signal Processing Magazine, 36, 132–160.
Kumar, S. M., & Majumder, D. (2018). Healthcare solution based on machine learning applications in IoT and edge computing. International Journal of Pure and Applied Mathematics, 119(16), 1473–1484.
Gillies, R., Kinahan, P., et al. (2016). Radiomics: Images are more than pictures, they are data. Radiology, 278(2), 563–577.
Folorunso, S. O., & Adeyemo, A. B. (2012). Theoretical comparison of undersampling techniques against. In EIE’s 2nd International Conference on Computing, Energy, Networking, Robotics and Telecommunication (EIE 2012).
Chawla, N., Bowyer, K., Hall, L., & Kegelmeyer, P. (2002). SMOTE: Synthetic minority over-sampling technique. Journal of Artificial Intelligence Research, 16, 321–357.
Wilson, D. L. (1972). Asymptotic properties of nearest neighbour rules using edited data. IEEE Transactions on Systems, Man, and Cybernetics, 2, 408–421.
Tomek, I. (1976). An experiment with the edited nearest-neighbor rule. IEEE Transactions on Systems, Man, and Cybernetics, 6(6), 448–452.
He, H., Bai, Y., Garcia, E. A., & Li, S. (2008). ADASYN: Adaptive synthetic sampling approach for imbalanced learning. In IEEE International Joint Conference Neural Networks, Hong Kong.
Vallières, M., Kay-Rivest, E., Perrin, L. J., Liem, X., Furstoss, C., Aerts, H. J. W. L., Khaouam, N., Nguyen-Tan, P. F., Wang, C. S., Sultanem, K., Seuntjens, J., & El Naqa, I. (2017). Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer. Scientific Reports, 7(1), 10117.
Pedregosa, F., Varoquaux, G., Gramfort, A., Michel, V., Thirion, B., Grisel, O., Blondel, M., Prettenhofer, P., Weiss, R., Dubourg, V., Vanderplas, J., Passos, A., Cournapeau, D., Brucher, M., Perrot, M., & Duchesnay, E. (2011). Scikit-learn: Machine learning in python. Journal of Machine Learning Research, 12, 2825–2830.
Vapnik, V. N. (1998). Adaptive and learning systems for signal processing communications, and control. In Statistical learning theory.
https://github.com/ieee8023/covid-chestxray-dataset. [Online].
https://commons.wikimedia.org/wiki/Category:Magnetic_resonance_imaging#/media/File:Petmr.jpg
https://en.wikipedia.org/wiki/X-ray_machine#/media/File:Projectional_radiography_components.jpg
https://en.wikipedia.org/wiki/CT_scan#/media/File:UPMCEast_CTscan.jpg
https://en.wikipedia.org/wiki/Medical_ultrasound#/media/File:AlokaPhoto2006a.jpg
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Folorunso, S.O., Awotunde, J.B., Ayo, F.E., Abdullah, KK.A. (2021). RADIoT: The Unifying Framework for IoT, Radiomics and Deep Learning Modeling. In: Kumar Bhoi, A., Mallick, P.K., Narayana Mohanty, M., Albuquerque, V.H.C.d. (eds) Hybrid Artificial Intelligence and IoT in Healthcare. Intelligent Systems Reference Library, vol 209. Springer, Singapore. https://doi.org/10.1007/978-981-16-2972-3_6
Download citation
DOI: https://doi.org/10.1007/978-981-16-2972-3_6
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-16-2971-6
Online ISBN: 978-981-16-2972-3
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)