Development of AC and DC Drive Coils for a Small Volume Magnetic Particle Imaging System
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Recent development in a new imaging modality called Magnetic Particle Imaging (MPI) technique has attracted much interests from researchers where it is expected to provide a higher spatial and temporal resolutions of images. The MPI technique works by utilizing an AC field to modulate the magnetic response from magnetic nanoparticles and a gradient DC field to localize the magnetic nanoparticles, where the characteristics of AC and DC fields affect the performance of MPI technique. The purpose of this study is to develop compact DC and AC drive coils as a preliminary step towards implementation in a small volume MPI system. The AC drive coil is designed based on a Helmholtz-coil configuration and resonated at a frequency to lower its circuit impedance. The gradient DC field is realized by combination of permanent magnets and a DC coil to shift a Flux Free Line (FFL) vertically. A 3rd-order Butterworth low-pass filter is implemented in the DC drive coil circuit to protect its DC current source from high-frequency field induction. The AC drive coil is able to be resonated at the designed frequency of 8 kHz and fairly good horizontal and vertical gradient DC fields are obtained. The DC drive coil is able to shift the FFL vertically at 0.33 mm/A and further improvement can be expected in the coil design for future implementation in the small volume MPI system.
KeywordsCoil Resonance Low pass filter Magnetic particle imaging
This work was supported by Research Management Center of Universiti Malaysia Pahang under grant number of RDU170377.
- 3.Bakenecker AC, Ahlborg M, Debbeler C et al (2018) Magnetic particle imaging in vascular medicine. Innov Surg Sci 3:179–192Google Scholar
- 4.Yu EY, Bishop M, Zheng B et al (2017) Magnetic particle imaging: a novel in vivo imaging platform for cancer detection. Nano Lett 17. https://doi.org/10.1021/acs.nanolett.6b04865
- 9.Croft LR, Goodwill PW, Konkle JJ et al (2016) Low drive field amplitude for improved image resolution in magnetic particle imaging. Med Phys 43. https://doi.org/10.1118/1.4938097
- 11.Konkle JJ, Goodwill PW, Hensley DW, et al (2015) A convex formulation for magnetic particle imaging X-space reconstruction. PLoS One 10. https://doi.org/10.1371/journal.pone.0140137
- 12.Shah SA, Ferguson RM, Krishnan KM (2014) Slew-rate dependence of tracer magnetization response in magnetic particle imaging. J Appl Phys 116. https://doi.org/10.1063/1.4900605
- 13.Bauer LM, Situ SF, Griswold MA, Samia ACS (2015) Magnetic particle imaging tracers: state-of-the-art and future directions. J Phys Chem Lett 6Google Scholar
- 18.Colombo S, Lebedev V, Tonyushkin A et al (2016) Towards a mechanical MPI scanner based on atomic magnetometry. 1–6Google Scholar
- 22.Bauer LM, Hensley DW, Zheng B et al (2016) Eddy current-shielded x-space relaxometer for sensitive magnetic nanoparticle characterization. Rev Sci Instrum 87. https://doi.org/10.1063/1.4950779
- 23.Tsukada K, Tsunashima K, Jinno K et al (2019) Using magnetic field gradients to shorten the antigen-antibody reaction time for a magnetic immunoassay. IEEE Trans Magn 1–5. https://doi.org/10.1109/tmag.2019.2894904
- 24.Saari MM, Suhaimi NS, Razali S et al (2018) Development of a resonant excitation coil of AC magnetometer for evaluation of magnetic fluid. J Telecommun Electron Comput Eng 10Google Scholar
- 25.Saari MM, Suhaimi NS, Lah NAC et al (2018) A sensitive AC magnetometer using a resonant excitation coil for magnetic fluid characterization in nonlinear magnetization region. In: 2018 IEEE international magnetics conference (INTERMAG). IEEE, pp 1–4Google Scholar