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Carbon Nanotubes in Controlled Drug Delivery

  • Md Saquib HasnainEmail author
  • Amit Kumar Nayak
Chapter
Part of the SpringerBriefs in Applied Sciences and Technology book series (BRIEFSAPPLSCIENCES)

Abstract

During past few decades, CNTs have been attracted a lot of attentiveness owing to their capability to deliver drug molecules to a particular site in a controlled manner (Luo et al., Biomaterials 32:6316–6323, 2011). Consequently, these are used to provide both controlled drug delivery as well as genetic substances like DNA, genes, and antibodies.

References

  1. E.J. Anglin, L. Cheng, W.R. Freeman, M.J. Sailor, Porous silicon in drug delivery devices and materials. Adv. Drug Deliv. Rev. 60, 1266–1277 (2008)CrossRefGoogle Scholar
  2. A. Bianco, K. Kostarelos, C.D. Partidos, M. Prato, Biomedical applications of functionalised carbon nanotubes. Chem. Commun. 5, 571–577 (2005)CrossRefGoogle Scholar
  3. M. Goldberg, R. Langer, X. Jia, Nanostructured materials for applications in drug delivery and tissue engineering. J. Biomater. Sci. Polym. Ed. 18, 241–268 (2007)CrossRefGoogle Scholar
  4. S. Hampel, D. Kunze, D. Haase, K. Krämer, M. Rauschenbach, M. Ritschel, A. Leonhardt, J. Thomas, S. Oswald, V. Hoffmann Carbon nanotubes filled with a chemotherapeutic agent: a nanocarrier mediates inhibition of tumor cell growth (2008)Google Scholar
  5. T.A. Hilder, J.M. Hill, Modeling the loading and unloading of drugs into nanotubes. Small 5, 300–308 (2009)CrossRefGoogle Scholar
  6. X. Luo, C. Matranga, S. Tan, N. Alba, X.T. Cui, Carbon nanotube nanoreservior for controlled release of anti-inflammatory dexamethasone. Biomaterials 32, 6316–6323 (2011)CrossRefGoogle Scholar
  7. M. Malmsten, Soft drug delivery systems. Soft Matter 2, 760–769 (2006)CrossRefGoogle Scholar
  8. A.K. Nayak, Controlled release drug delivery systems. Sci. J. UBU. 2, 1–8 (2011)Google Scholar
  9. A.K. Nayak, S.A. Ahmad, S. Beg, T.J. Ara, M.S. Hasnain, Drug delivery: Present, past and future of medicine, in, Applications of Nanocomposite Materials in Drug Delivery, (Elsevier, 2018), pp. 255–282Google Scholar
  10. A.K. Nayak, H. Bera, In situ polysaccharide-based gels for topical drug delivery applications, in Polysaccharide Carriers for Drug Delivery (Elsevier, 2019), pp. 615–638Google Scholar
  11. A.K. Nayak, B. Das, Introduction to polymeric gels, in Polymeric Gels (Elsevier, 2018), pp 3–27Google Scholar
  12. I.B. Neagoe, C. Braicu, C. Matea, C. Bele, G. Florin, K. Gabriel, C. Veronica, A. Irimie, Efficient siRNA delivery system using carboxilated single-wall carbon nanotubes in cancer treatment. J. Biomed. Nanotechnol. 8, 567–574 (2012)CrossRefGoogle Scholar
  13. J. Malakar, A. Basu, A.K. Nayak, Candesartan cilexetil microemulsions for transdermal delivery: Formulation, in-vitro skin permeation and stability assessment. Curr. Drug Deliv. 11, 313–321 (2014)CrossRefGoogle Scholar
  14. M. Prato, K. Kostarelos, A. Bianco, Functionalized carbon nanotubes in drug design and discovery. Acc. Chem. Res. 41, 60–68 (2007)CrossRefGoogle Scholar
  15. C. Tripisciano, S. Costa, R. Kalenczuk, E. Borowiak-Palen, Cisplatin filled multiwalled carbon nanotubes–a novel molecular hybrid of anticancer drug container. Eur. Phys. J. B 75, 141–146 (2010a)CrossRefGoogle Scholar
  16. C. Tripisciano, M.H. Rümmeli, X. Chen, E. Borowiak-Palen, Multi-wall carbon nanotubes–a vehicle for targeted Irinotecan drug delivery. Phys. Status Solidi (b) 247, 2673–2677 (2010b)CrossRefGoogle Scholar
  17. W. Yang, P. Thordarson, J.J. Gooding, S.P. Ringer, F. Braet, Carbon nanotubes for biological and biomedical applications. Nanotechnology 18, 412001 (2007)CrossRefGoogle Scholar
  18. Y.-J. Yang, X. Tao, Q. Hou, J.-F. Chen, Fluorescent mesoporous silica nanotubes incorporating CdS quantum dots for controlled release of ibuprofen. Acta Biomater. 5, 3488–3496 (2009)CrossRefGoogle Scholar
  19. A.M. Yusof, N.A. Buang, L.S. Yean, M.L. Ibrahim, The use of multi‐walled carbon nanotubes as possible carrier in drug delivery system for aspirin, in AIP Conference Proceedings (AIP, 2009), pp. 390–394Google Scholar

Copyright information

© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of PharmacyShri Venkateshwara UniversityAmrohaIndia
  2. 2.Department of PharmaceuticsSeemanta Institute of Pharmaceutical ScienceMayurbhanjIndia

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