Supportive Therapy

  • Michihiro YanoEmail author


Proper supporting therapy for malignant patients is important for pain relief, safety of treatment, and improvement of treatment efficacy. This chapter focuses on the following three areas of supporting therapy.
  1. 1.

    Tumor lysis syndrome.

  2. 2.

    Chemotherapy-induced nausea and vomiting.

  3. 3.

    Cancer pain management.



Supporting therapy Supportive care Tumor lysis syndrome Hyperuricemia Antiemetic agents Persistent cancer pain Analgesics Opioids 


  1. 1.
    Cairo MS, Coiffier B, Reiter A, Younes A, Expert Panel TLS. Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus. Br J Med. 2010;149:578–86.Google Scholar
  2. 2.
    Hesketh PJ, Kris MG, Grungerg SM, Hainsworth JD, Harker G, Aapro MS, Gandara D, Lindley CM. Proposal for classifying the acute emetogenicity of cancer chemotherapy. J Clin Oncol. 1997;15:103–9.CrossRefGoogle Scholar
  3. 3.
    WHO guidelines on the pharmacological treatment of persisting pain in children with medical illness. 2012.

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Department of PediatricsAkita University HospitalAkitaJapan

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