The basic aim of delivering radical radiotherapy is to deliver maximum dose to the target while sparing normal tissues as much as possible. Knowledge about the 6Rs of radiotherapy namely repair of sublethal damage in normal tissues, reoxygenation of the tumor cells, redistribution of the tumor cells into more radiosensitive phase, radiosensitivity, and remote (bystander effect) is very important in achieving this goal. The chapter describes the 6Rs of radiotherapy and its clinical significance.
KeywordsRepair Reoxygenation Redistribution Repopulation
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