Abruption and Preterm Labor

  • Seishi Furukawa
Part of the Comprehensive Gynecology and Obstetrics book series (CGO)


Placental abruption accounts for 5–10% of all preterm deliveries and is more common in cases involving a lower gestational age. The incidence of placental abruption is highest at earlier gestational age (7–18%, 24–30 weeks of gestation) and then decreases and reaches <1.0% around 36 weeks.

Cigarette smoking, parity (grand multiparity), hypertensive disorders, and preterm premature rupture of membranes are found to be independent factors associated with the development of preterm placental abruptions. In the late preterm period, prognosis tends to deteriorate especially in cases of placental abruption preceded by hypertensive disorders. Furthermore, preceding clinical manifestations such as preterm premature rupture of membranes or hypertensive disorders may not have less of an influence on prognosis at the early preterm period. An understanding of the etiology involving the development of placental abruption, its frequency, and its effect on prognosis should lead to better management of preterm labor.


Preterm birth Placental abruption Inflammation pathway Ischemic pathway 


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© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Seishi Furukawa
    • 1
  1. 1.Department of Obstetrics and Gynecology, Faculty of medicineUniversity of MiyazakiMiyazakiJapan

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