Advertisement

Epidemiology of SFTS Virus from Ticks and Animals in the Republic of Korea

  • Jun-Gu Kang
  • Myoung-don Oh
  • Youngmee Jee
  • Joon-Seok ChaeEmail author
Chapter

Abstract

Except for human data on severe fever with thrombocytopenia syndrome virus (SFTSV) infection, the first detection of SFTSV antigen was reported in a tick collected from vegetation in 2014 and the first SFTSV isolate derived from tick was identified in 2016. The range of SFTSV minimum field infection rate (MFIR) for ticks collected from vegetation in the Republic of Korea (ROK) was 0.10%~0.46% and similar to that (0.2%) in China. In addition, the SFTSV antigen was detected in ticks collected from wild mammals and reptiles and the infection rate (IR) of SFTSV were 4.98% and 3.57%, respectively. In animals, SFTSV was detected from sera of dogs, cats, Korean water deer, and wild boars. The range of infection rate of SFTSV antigen and antibody were 0.23–17.46% and 6.59–13.85%, respectively. These studies including human data indicate that the ROK is an endemic area as well as China and Japan and SFTSV is circulating among several species of animals and ticks throughout ROK. However, the natural cycle of SFTSV has not yet been established. Therefore, further studies should be conducted to investigate the surveillance of SFTSV in various animals and to monitor the prevalence of SFTSV in natural environment steadily.

Keywords

Severe fever with thrombocytopenia syndrome virus Tick Animals Republic of Korea 

References

  1. Chae JB, Kang JG, Kim HC, Chong ST, Lee IY, Shin NS, Chae JS (2017a) Identification of tick species collected from wild boars and habitats of wild boars and domestic pigs in the Republic of Korea. Korean J Parasitol 55(2):185–191CrossRefGoogle Scholar
  2. Chae JB, Kim TH, Jung JH, Park YJ, Park JH, Choi KS, Yu DH, Park BK, Chae JS (2017b) Prevalence of severe fever with thrombocytopenia syndrome virus among ticks surveyed at Mt. Gwanak, Korea. Korean J Vet Res 57(3):169–174Google Scholar
  3. Chong ST, Kim HC, Lee IY, Kollars TM Jr, Sancho AR, Sames WJ, Chae JS, Klein TA (2013) Seasonal distribution of ticks in four habitats near the demilitarized zone, Gyeonggi-do (Province), Republic of Korea. Korean J Parasitol 51(3):319–325CrossRefGoogle Scholar
  4. Guglielmone AA, Robbins RG, Apanaskevich DA, Petney TN, Estrada-Pena A, Horak IG, Shao R, Barker SC (2010) The Argasidae, Ixodidae and Nuttalliellidae (Acari: Ixodida) of the world: a list of valid species names. Zootaxa 528:1–28CrossRefGoogle Scholar
  5. Ham H, Jo S, Jang J, Choi S (2014) No detection of severe fever with thrombocytopenia syndrome virus from ixodid ticks collected in Seoul. Korean J Parasitol 52(2):221–224CrossRefGoogle Scholar
  6. Hwang J, Kang JG, Oh SS, Chae JB, Cho YK, Cho YS, Lee H, Chae JS (2017) Molecular detection of severe fever with thrombocytopenia syndrome virus (SFTSV) in feral cats from Seoul, Korea. Ticks Tick Borne Dis 8(1):9–12CrossRefGoogle Scholar
  7. Kang JG, Kim HC, Choi CY, Nam HY, Chae HY, Chong ST, Klein TA, Ko S, Chae JS (2013) Molecular detection of Anaplasma, Bartonella, and Borrelia species in ticks collected from migratory birds from Hong-do Island, Republic of Korea. Vector-Borne Zoo Dis 13:215–225CrossRefGoogle Scholar
  8. Kang JG, Ko S, Kim HC, Chong ST, Klein TA, Chae JB, Jo YS, Choi KS, Yu DH, Park BK, Park J, Chae JS (2016) Prevalence of Anaplasma and Bartonella spp. in ticks collected from Korean water deer (Hydropotes inermis argyropus). Korean J Parasitol 54:87–91CrossRefGoogle Scholar
  9. Kim CM, Yi YH, Yu DH, Lee MJ, Cho MR, Desai AR, Shringi S, Klein TA, Kim HC, Song JW, Baek LJ, Chong ST, O’guinn ML, Lee JS, Lee IY, Park JH, Foley J, Chae JS (2006) Tick-borne rickettsial pathogens in ticks and small mammals in Korea. Appl Environ Microbiol 72:5766–5776CrossRefGoogle Scholar
  10. Kim HC, Han SH, Chong ST, Klein TA, Choi CY, Nam HY, Chae HY, Lee H, Ko S, Kang JG, Chae JS (2011) Ticks collected from selected mammalian hosts surveyed in the Republic of Korea during 2008–2009. Korean J Parasitol 49(3):331–335CrossRefGoogle Scholar
  11. Kim BJ, Kim H, Won S, Kim HC, Chong ST, Klein TA, Kim KG, Seo HY, Chae JS (2014) Ticks collected from wild and domestic animals and natural habitats in the Republic of Korea. Korean J Parasitol 52(3):281–285CrossRefGoogle Scholar
  12. Lee SH, Kim HJ, Byun JW, Lee MJ, Kim NH, Kim DH, Kang HE, Nam HM (2017a) Molecular detection and phylogenetic analysis of severe fever with thrombocytopenia syndrome virus in shelter dogs and cats in the Republic of Korea. Ticks Tick Borne Dis 8(4):626–630CrossRefGoogle Scholar
  13. Lee SH, Kim HJ, Lee MJ, Byun JW, Kim DY, Kim NH, Kim DH, Kwak D, Kang HE, Nam HM (2017b) Prevalence of antibodies against severe fever with thrombocytopenia syndrome virus in shelter dogs in the Republic of Korea. Ticks Tick Borne Dis.  https://doi.org/10.1016/j.ttbdis.2017.09.002 CrossRefGoogle Scholar
  14. Luo LM, Zhao L, Wen HL, Zhang ZT, Liu JW, Fang LZ, Xue ZF, Ma DQ, Zhang XS, Ding SJ, Lei XY, Yu XJ (2015) Haemaphysalis longicornis ticks as reservoir and vector of severe fever with thrombocytopenia syndrome virus in China. Emerg Infect Dis 21(10):1770–1776CrossRefGoogle Scholar
  15. Oh JY, Moon BC, Bae BK, Shin EH, Ko YH, Kim YJ, Park YH, Chae JS (2009) Genetic identification and phylogenetic analysis of Anaplasma and Ehrlichia species in Haemaphysalis longicornis collected from Jeju Island, Korea. J Bacteriol Virol 39:1–11CrossRefGoogle Scholar
  16. Oh SS, Chae JB, Kang JG, Kim HC, Chong ST, Shin JH, Hur MS, Suh JH, Oh MD, Jeong SM, Shin NS, Choi KS, Chae JS (2016) Detection of severe fever with thrombocytopenia syndrome virus from wild animals and Ixodidae ticks in the Republic of Korea. Vector Borne Zoonotic Dis 16(6):408–414.CrossRefGoogle Scholar
  17. Park SW, Song BG, Shin EH, Yun SM, Han MG, Park MY, Park C, Ryou J (2014) Prevalence of severe fever with thrombocytopenia syndrome virus in Haemaphysalis longicornis ticks in South Korea. Ticks Tick Borne Dis 5(6):975–977CrossRefGoogle Scholar
  18. Suh JH, Kim HC, Yun SM, Lim JW, Kim JH, Chong ST, Kim DH, Kim HT, Kim H, Klein TA, Johnson JL, Lee WJ (2016) Detection of SFTS virus in Ixodes nipponensis and Amblyomma testudinarium (Ixodida: Ixodidae) collected from reptiles in the Republic of Korea. J Med Entomol 53(3):584–590CrossRefGoogle Scholar
  19. Yun SM, Lee YJ, Choi W, Kim HC, Chong ST, Chang KS, Coburn JM, Klein TA, Lee WJ (2016a) Molecular detection of severe fever with thrombocytopenia syndrome and tick-borne encephalitis viruses in ixodid ticks collected from vegetation, Republic of Korea, 2014. Ticks Tick Borne Dis 7(5):970–978CrossRefGoogle Scholar
  20. Yun SM, Song BG, Choi W, Roh JY, Lee YJ, Park WI, Han MG, Ju YR, Lee WJ (2016b) First isolation of severe fever with thrombocytopenia syndrome virus from Haemaphysalis longicornis ticks collected in severe fever with thrombocytopenia syndrome outbreak areas in the Republic of Korea. Vector Borne Zoonotic Dis 16(1):66–70CrossRefGoogle Scholar
  21. Yun SM, Park SJ, Park SW, Choi W, Jeong HW, Choi YK, Lee WJ (2017) Molecular genomic characterization of tick- and human-derived severe fever with thrombocytopenia syndrome virus isolates from South Korea. PLoS Negl Trop Dis 11(9):e0005893CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Jun-Gu Kang
    • 1
  • Myoung-don Oh
    • 2
  • Youngmee Jee
    • 3
  • Joon-Seok Chae
    • 1
    Email author
  1. 1.Laboratory of Veterinary Internal Medicine, College of Veterinary MedicineSeoul National UniversitySeoulRepublic of Korea
  2. 2.Department of Internal MedicineSeoul National University College of MedicineSeoulRepublic of Korea
  3. 3.Center for Infectious Disease Research, Korea National Institute of HealthCheongju-siRepublic of Korea

Personalised recommendations