Associations of Indoor CO2 Concentration with Sleep Quality and Other Human Responses

  • Guanzhang Luo
  • Xiaojing ZhangEmail author
  • Jingchao Xie
  • Dandan Li
Conference paper
Part of the Environmental Science and Engineering book series (ESE)


This paper summarizes current literature evidence on the associations of indoor carbon dioxide (CO2) with sleep quality and other human responses at dorms, bedrooms or other sleeping environments. Published literature was identified by searching Web of Science and Google Scholar, using the following keywords including carbon dioxide, sleep quality, ventilation rate, indoor air quality, and health effect. From selected studies, detailed findings were summarized based on subjective assessments and objective measurements. The collected data were then tabulated to observe the associations of CO2 concentration with sleep quality and other human responses. Furthermore, the potential confounding of researches was discussed. The results of the reviewed studies show that there was a tendency that lower CO2 concentration improved sleep quality. Given the findings of this summary, effects of indoor CO2 concentration on sleep quality are worthy for further study to elaborate the dose-response relationship between CO2 concentration and human responses during sleep and “no-effect” threshold of CO2 concentration for good sleeping environment requires further research.


Carbon dioxide Ventilation rate Sleep quality Indoor air quality Health effect 



This study was financially supported by National Natural Science Foundation of China (No. 51708006) and Foundation for Top Youth Team of Beijing Educational Committee.


  1. 1.
    Azuma, K., Kagi, N., Yanagi, U.: Effects of low-level inhalation exposure to carbon dioxide in indoor environments: a short review on human health and psychomotor performance. Environ. Int. 121, 51–56 (2018)CrossRefGoogle Scholar
  2. 2.
    Seppänen, O.A., Fisk, W.J., Mendell, M.J.: Association of ventilation rates and CO2 concentrations with health and other responses in commercial and institutional buildings. Indoor Air 9(4), 226–252 (1999)CrossRefGoogle Scholar
  3. 3.
    Zhang, X., Wargocki, P., Lian, Z.: Effects of exposure to carbon dioxide and bioeffluents on perceived air quality, self-assessed acute health symptoms, and cognitive performance. Indoor Air 27(1), 47–64 (2017)CrossRefGoogle Scholar
  4. 4.
    Alberts, W.M.: Indoor air pollution: NO, NO2, CO, and CO2. J. Allergy Clin. Immunol. 94(2), 289–295 (1994)CrossRefGoogle Scholar
  5. 5.
    Pettenkoffer, M.V.: Über den Luftwechsel in Wohngebäuden. Cottasche Buchhandlung, Muenchen (1858)Google Scholar
  6. 6.
    Chatzidiakou, L., Mumovic, D., Summerfield, A.: Is CO2 a good proxy for indoor air quality in classrooms? Part 1: The interrelationships between thermal conditions, CO2 levels, ventilation rates and selected indoor pollutants. Build. Serv. Eng. Res. Technol. 36(2), 129–161 (2015)CrossRefGoogle Scholar
  7. 7.
    Myhrvold, A.N., Olsen, E., Lauridsen, O.: Indoor environment in schools-pupils health and performance in regard to CO2 concentrations. Indoor Air 96(4), 369–371 (1996)Google Scholar
  8. 8.
    Coley, D.A., Greeves, R., Saxby, B.K.: The effect of low ventilation rates on the cognitive function of a primary school class. Int. J. Vent. 6(2), 107–112 (2007)CrossRefGoogle Scholar
  9. 9.
    Zhang, X., Wargocki, P., Lian, Z.: Physiological responses during exposure to carbon di-oxide and bioeffluents at levels typically occurring indoors. Indoor Air 27(1), 65–77 (2017)CrossRefGoogle Scholar
  10. 10.
    Urlaub, S., Grün, G., Foldbjerg, P.: The influence of the indoor environment on sleep quality. In: Proceedings of Healthy Buildings Europe 2015. Eindhoven, The Netherlands (2015)Google Scholar
  11. 11.
    Strøm-Tejsen, P., Zukowska, D., Wargocki, P.: The effects of bedroom air quality on sleep and next-day performance. Indoor Air 26(5), 679–686 (2016)CrossRefGoogle Scholar
  12. 12.
    Canha, N., Lage, J., Candeias, S.: Indoor air quality during sleep under different ventilation patterns. Atmos. Pollut. Res. 8(6), 1132–1142 (2017)CrossRefGoogle Scholar
  13. 13.
    Lan, L., Qian, X.L., Lian, Z.W.: Local body cooling to improve sleep quality and thermal comfort in a hot environment. Indoor Air 28(1), 135–145 (2018)CrossRefGoogle Scholar
  14. 14.
    Laverge, J., Janssens, A.: IAQ exposure of sleeping occupants under different residential ventilation configurations. In: 12th International Conference on Air Distribution in Rooms (Roomvent 2011). Tapir Academic Press (2011)Google Scholar
  15. 15.
    Bekö, G., Lund, T., Nors, F.: Ventilation rates in the bedrooms of 500 Danish children. Build. Environ. 45(10), 2289–2295 (2010)CrossRefGoogle Scholar
  16. 16.
    BSR/ASHRAE Standard 62-1989: Ventilation for Acceptable Indoor Air Quality. ASHRAE, Atlanta (1989)Google Scholar
  17. 17.
    Wargocki, P., Lan, L., Lian, Z.: Thermal environment, IAQ and sleep. ASHRAE J. 60(4), 60–63 (2018)Google Scholar
  18. 18.
    Strøm-Tejsen, P., Wargocki, P., Wyon, D. P.: The effect of air quality on sleep. In: 13th International Conference on Indoor Air Quality and Climate-Indoor Air 2014. International Society for Indoor Air Quality and Climate (ISIAQ). HA0506. Hong Kong, China (2014)Google Scholar
  19. 19.
    Strøm-Tejsen, P., Wargocki, P., Wyon, D. P.: The effect of CO2 controlled bedroom ventilation on sleep and next-day performance. In: 13th SCANVAC International Conference on Air Distribution in Rooms: New Ventilation Strategies Based in Active and Passive Technology in Buildings and for Comfort in Airplanes, p. 148. Sao Paulo, Brazil (2014)Google Scholar
  20. 20.
    Laverge, J., Janssens, A.: Analysis of the influence of ventilation rate on sleep pattern. In: Proceedings of Indoor Air 2011, pp. 51–53. Austin, TX, USA (2011)Google Scholar
  21. 21.
    Zhang, N., Cao, B., Zhu, Y.: Indoor environment and sleep quality: a research based on online survey and field study. Build. Environ. 137, 198–207 (2018)CrossRefGoogle Scholar
  22. 22.
    Zhu, M.L., Ouyang, Q., Shen, H.G.: Field study on the objective evaluation of sleep quality and sleeping thermal environment in summer. Energy Build. 133, 843–852 (2016)CrossRefGoogle Scholar
  23. 23.
    Mishra, A.K., van Ruitenbeek, A.M., Loomans, M.G.L.C.: Window/door opening-mediated bedroom ventilation and its impact on sleep quality of healthy, young adults. In-door. Air. 28(2), 339–351 (2018)Google Scholar
  24. 24.
    Cremers, B.: Effect of CO2 on restlessness of an Alzheimer patient. REHVA J. 5, 41–44 (2015)Google Scholar
  25. 25.
    Margel, D., White, D.P., Pillar, G.: Long-term intermittent exposure to high ambient CO2 causes respiratory disturbances during sleep in submariners. Chest 124(5), 1716–1723 (2003)CrossRefGoogle Scholar
  26. 26.
    Sekhar, S.C., Goh, S.E.: Thermal comfort and IAQ characteristics of naturally/mechanically ventilated and air-conditioned bedrooms in a hot and humid climate. Build. Environ. 46(10), 1905–1916 (2011)CrossRefGoogle Scholar
  27. 27.
    Canha, N., Lage, J., Belo, J.: Is the air that we breathe during sleep affecting our sleep quality? In: 15th Conference of the International Society of Indoor Air Quality and Climate Indoor Air 2018, p. 717. Philadelphia, PA, USA (2018)Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Guanzhang Luo
    • 1
  • Xiaojing Zhang
    • 1
    Email author
  • Jingchao Xie
    • 1
  • Dandan Li
    • 1
  1. 1.Key Laboratory of Green Built Environment and Energy Efficient TechnologyBeijing University of TechnologyBeijingChina

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