Magnetic Resonance Spectroscopic Analysis in Brain Tumors

  • Ghazaleh Jamalipour Soufi
  • Nastaran Fallahpour
  • Kaveh Jamalipour Soufi
  • Siavash Iravani


Magnetic resonance spectroscopy (MRS) can be applied for analyzing and evaluating the treatment response to human brain tumors. It is a valuable and noninvasive technique for identifying metabolites including choline-containing compounds, N-acetyl aspartate, lactate, and creatine/phosphocreatine. This technique provides important clinical information allowing more specific diagnosis, including differentiating the brain tumors from abscesses, identifying the tumoral characteristic of the studied lesion, better characterizing brain tumors, and establishing an extended local assessment of morphological abnormalities detected in conventional magnetic resonance imaging (MRI). In this chapter, MRS (single- and multi-voxel) techniques in diagnosis, follow-up and analysis of brain tumors, and grading of primary brain tumors are highlighted.


Magnetic resonance spectroscopy Brain tumors Proton magnetic resonance spectroscopy MRI MRS Multi-voxel 1-H MRSI 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Ghazaleh Jamalipour Soufi
    • 1
  • Nastaran Fallahpour
    • 2
  • Kaveh Jamalipour Soufi
    • 2
  • Siavash Iravani
    • 3
  1. 1.Radiology DepartmentIsfahan University of Medical SciencesIsfahanIran
  2. 2.School of Medicine, Isfahan University of Medical SciencesIsfahanIran
  3. 3.Faculty of Pharmacy and Pharmaceutical SciencesIsfahan University of Medical SciencesIsfahanIran

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