Taurine 11 pp 313-321 | Cite as

Relationships Between the Purposes of Taurine-Contained Nutritional Drink Intake and Lifestyle Habits: A Cross-Sectional Survey of Workers in Japan

  • Makoto Ohtsuki
  • Akinobu Nishimura
  • Toshihiro Kato
  • Yusuke Wakasugi
  • Rie Nagao-Nishiwaki
  • Tomiko Shibata
  • Hiromi Okada
  • Takeshi Ohkubo
  • Ning MaEmail author
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1155)


This study surveyed that the relationship between the frequencies of intake of taurine-contained nutritional drinks (TCND), and lifestyle and the purposes of intake it. The study was conducted a cross-sectional survey using 265 people (203 male, 62 female) aged 18–64 worked in two companies in Mie Prefecture, Japan between December 2017 and February 2018. The questionnaires gathered characteristics, demographic, socioeconomic, lifestyle habits and purpose of TCND intake. We divided the frequency of intake of TCND of at least a few times every month as the high-frequency TCND (HF-TCND) group, and the remaining as the low-frequency TCND (LF-TCND) group. Multivariate logistic regression analysis was used to investigate the relationship between characteristics, demographic, socioeconomic, lifestyle habits and purpose of TCND intake and HF-TCND after controlling for individual variables. Of all participants, 13.4% was evaluated as HT-CND. 16.3% for male or 4.3% for female were evaluated as HF-TCND (p < 0.05). The most reason for frequent choosing a TCND was fatigue recovery. Logistic regression analysis showed that sex, occupation, purpose of TCND intake and stressful are related to HF-TCND. Our study indicates that purpose of TCND intake, such as fatigue recovery and reducing stress, may partly affect the frequency of intake of TCND. Therefore, we must continue to show scientific evidence for taurine by enlightenment activity etc.


Taurine-contained nutritional drinks Cross-sectional survey Workers Lifestyle habits Fatigue recovery 



Taurine-contained nutritional drinks


High-frequency TCND


Low-frequency TCND


Odds ratios


Confidence intervals



The authors thank all of the participants in this study.


  1. Azuma J, Sawamura A, Awata N, Ohta H, Hamaguchi T, Harada H, Takihara K, Hasegawa H, Yamagami T, Ishiyama T, Iwataet H, Kishimoto S (1985) Therapeutic effect of taurine in congestive heart failure: a double-blind crossover trial. Clin Cardiol 8:276–282CrossRefGoogle Scholar
  2. Barclay JK, Hansel M (1991) Free radicals may contribute to oxidative skeletal muscle fatigue. Can J Physiol Pharmacol 69:279–284CrossRefGoogle Scholar
  3. Breda JJ, Whiting SH, Encarnação R, Norberg S, Jones R, Reinap M, Jewell J (2014) Energy drink consumption in Europe: a review of the risks, adverse health effects, and policy options to respond. Front Public Health 2:134CrossRefGoogle Scholar
  4. Eley DW, Lake N, ter Keurs HE (1994) Taurine depletion and excitation-contraction coupling in rat myocardium. Circ Res 74:1210–1219CrossRefGoogle Scholar
  5. Hongo N, Fujishita M, Takahashi Y, Adachi Y, Takahashi J, Tominaga K, Miura N (2017) Daily fatigue-reducing effect of astaxathin—a randomized, placebo-controlled, double-blind, parallel-group study. Jpn Pharmacol Ther 45:61–72Google Scholar
  6. Huxtable RJ (1992) Physiological actions of taurine. Physiol Rev 72:101–163CrossRefGoogle Scholar
  7. Kendler BS (1989) Taurine: an overview of its role in preventive medicine. Prev Med 18:79–100CrossRefGoogle Scholar
  8. Logan AC, Wong C (2001) Chronic fatigue syndrome: oxidative stress and dietary modifications. Altern Med Rev 6:450–459PubMedGoogle Scholar
  9. Manuel y Keenoy B, Moorkens G, Vertommen J, De Leeuw I (2001) Antioxidant status and lipoprotein peroxidation in chronic fatigue syndrome. Life Sci 68:2037–2049CrossRefGoogle Scholar
  10. Matsuyama Y, Morita T, Higuchi M, Tsujii T (1983) The effect of taurine administration on patients with acute hepatitis. Prog Clin Biol Res 125:461–468PubMedGoogle Scholar
  11. Ministry of Health Labor and Welfare (2017) Newly designated quasi-drugs. Available at: Accessed 12 June 2018
  12. National Institute Health and Nutrition (2018) Information system on safety and effectiveness for health foods. Available at: Accessed 12 June 2018
  13. Nowak D, Jasionowski A (2015) Analysis of the consumption of caffeinated energy drinks among polish adolescents. Int J Environ Res Public Health 12:7910–7921CrossRefGoogle Scholar
  14. Sagara M, Murakami S, Mizushima S, Liu L, Mori M, Ikeda K, Nara Y, Yamori Y (2015) Taurine in 24-h urine samples is inversely related to cardiovascular risks of middle aged subjects in 50 populations of the world. Adv Exp Med Biol 803:623–636CrossRefGoogle Scholar
  15. Sivoňová M, Žitňanová I, Hlinčíková L, Škodáček I, Trebatická J, Ďuračková Z (2004) Oxidative stress in university students during examinations. Stress 7:183–188CrossRefGoogle Scholar
  16. Sturman JA (1993) Taurine in development. Physiol Rev 73:119–147CrossRefGoogle Scholar
  17. Takemoto D, Yasutake Y, Tomimori N, Ono Y, Shibata H, Hayashi J (2015) Sesame lignans and vitamin E supplementation improve subjective statuses and anti-oxidative capacity in healthy humans with feelings of daily fatigue. Glob J Health Sci 7:1–10CrossRefGoogle Scholar
  18. Vecchiet J, Cipollone F, Falasca K, Mezzetti A, Pizzigallo E, Bucciarelli T, De Laurentis S, Affaitati G, De Cesare D, Giamberardino MA (2003) Relationship between musculoskeletal symptoms and blood markers of oxidative stress in patients with chronic fatigue syndrome. Neurosci Lett 335:151–154CrossRefGoogle Scholar
  19. Yamori Y, Liu L, Ikeda K, Miura A, Mizushima S, Miki T, Nara Y, WHO-Cardiovascular Disease and Alimentary Comparison (CARDIAC) Study Group (2001) Distribution of twenty-four hour urinary taurine excretion and association with ischemic heart disease mortality in 24 populations of 16 countries: results from the WHO-CARDIAC study. Hypertens Res 24:453–457CrossRefGoogle Scholar
  20. Yamori Y, Taguchi T, Mori H, Mori M (2010) Low cardiovascular risks in the middle aged males and females excreting greater 24-hour urinary taurine and magnesium in 41 WHO-CARDIAC study populations in the world. J Biomed Sci 17(Suppl 1):S21CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Makoto Ohtsuki
    • 1
  • Akinobu Nishimura
    • 2
  • Toshihiro Kato
    • 3
  • Yusuke Wakasugi
    • 1
  • Rie Nagao-Nishiwaki
    • 4
  • Tomiko Shibata
    • 5
  • Hiromi Okada
    • 6
  • Takeshi Ohkubo
    • 7
  • Ning Ma
    • 4
    Email author
  1. 1.Department of Clinical NutritionSuzuka University of Medical ScienceSuzukaJapan
  2. 2.Department of Orthopedic and Sports MedicineMie University Graduate School of MedicineTsuJapan
  3. 3.Department of RehabilitationSuzuka Kaisei HospitalSuzukaJapan
  4. 4.Faculty of Nursing ScienceSuzuka University of Medical ScienceSuzukaJapan
  5. 5.Department of Public Health and Welfare, Mie Prefectural GovernmentSuzuka Public Health CenterSuzukaJapan
  6. 6.Department of Public Health and Welfare, Mie Prefectural GovernmentTsu Public Health CenterTsuJapan
  7. 7.Department of Health and NutritionSendai Shirayuri Women’s CollegeSendaiJapan

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