Hepatic Coagulopathy: Intricacies and Challenges

  • Rakhee Kar


Liver is an elegant factory which synthesizes several plasma proteins, transport proteins, and most of the clotting factors to name just a few of its immense synthetic function. Virtually every arm of the complex hemostatic pathway gets deranged in liver disease. Hence, it is quite natural to find abnormal tests of hemostasis in patients with chronic liver disease (CLD). A bleeding as well as a clotting tendency does exist simultaneously in liver disease. These are due to a set of complex and multifactorial process leading to a state of rebalanced hemostasis in stable cirrhosis patients [1].


Chronic liver disease (CLD) Coagulopathy Hemostasis Thrombocytopenia Rebalanced hemostasis 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Rakhee Kar
    • 1
  1. 1.Department of PathologyJawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia

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