Actin Polymerization in Apicomplexans: A Novel Perspective
In the current chapter, we summarize the major/novel findings that we had reported in the previous sections. We also provide the novel perspective about individual partners known to regulate actin polymerization/depolymerization in apicomplexans. We also summarize the major findings of our mathematical model, which is mainly highlighted on how and what helps cells to maintain an average size of the actin filaments within a species. This is particularly important, since excessive growth of filament can lead to cell lysis. Finally, we present our conclusions about the probable evolutionary pathway of actin and its regulators in apicomplexans, based on the current literature and our phylogeny analysis.
- 6.Madden T (2002) The BLAST sequence analysis tool. NCBI Handb [Internet]. 2002:1–18Google Scholar