Coscinium fenestratum: A Review on Phytochemicals and Pharmacological Properties

  • Muhammad TaherEmail author
  • Mohamad Shahreen Amri
  • Deny Susanti
  • Muhammad Badri Abdul Kudos
  • Anis Natasha Shafawi
  • Soraya Nur Yazid


Coscinium fenestratum has been used in the traditional medicine, especially in the Ayurvedic method of healing as this plant can be found vastly in the Western Ghats of India. The distribution of this plant is concentrated to the Southeast Asia including Sri Lanka, India, Cambodia, Vietnam, Peninsular Malaysia, Sumatra, West Java, Borneo, Northeast of Thailand and Laos. This review is related to the phytochemicals and pharmacological effects of C. fenestratum. The major chemical constituents present in this plant include alkaloids, flavonoids and steroids. The most important bio-active compound is the berberine, which is the most widely studied plant compound. This plant exerts several pharmacological effects including antidiabetic, anticancer, antibacterial, antimalarial, antioxidant, antihypertensive, antiulcer, neuroprotector and wound healing activities. This chapter is supported by in vitro and in vivo studies carried out from the year of 1970 to 2016, which are available from PubMed, ScienceDirect, Google Scholar and Scopus.


Antidiabetic Berberine Coscinium fenestratum Pharmacology Phytochemicals 



The authors are thankful to the International Islamic University Malaysia for funding through grant no RIGS15-095-0095 and P-RIGS18-028-0028.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Muhammad Taher
    • 1
    Email author
  • Mohamad Shahreen Amri
    • 1
  • Deny Susanti
    • 2
  • Muhammad Badri Abdul Kudos
    • 1
  • Anis Natasha Shafawi
    • 2
  • Soraya Nur Yazid
    • 2
  1. 1.Department of Pharmaceutical Technology, Faculty of PharmacyInternational Islamic University MalaysiaKuantanMalaysia
  2. 2.Department of Chemistry, Faculty of ScienceInternational Islamic University MalaysiaKuantanMalaysia

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