Chemistry and Synthetic Overview of Flavonoids
Flavonoids are widely distributed secondary metabolites in plants that are known to be present in different vegetables and fruits. The flavonoid groups include various subclasses of compounds such as flavanones, flavones, dihydroflavonols, flavonols, flavan-3-ols, anthocyanidins, isoflavones, proanthocyanidins, and chalcones with a C6-C3-C6 structure. These compounds are considered to be imperative structural motifs owing to their distinctive way of physiological action and biochemical effects in humans as well as in plants. Keeping in view of their immense importance and physiological roles, the summation of the structural features is quintessential for their therapeutic applications. Furthermore, the structure-activity relationship together with their chemical and biochemical synthetic preview could help the scientific community to explore and design novel drugs. Therefore, structural features of flavonoids may prompt a great deal of attention in the field of organic synthesis and biology to study innovative methods of synthesis and therapeutic applications.
KeywordsFlavonoids Structural features Structure-activity relationship (SAR)
The authors would like to acknowledge the assistance of Career Point University, in Tikker – kharwarian, Hamirpur, Himachal Pradesh, and Maharishi Markandeshwar (deemed to be university) in Mullana, Ambala, Haryana, for providing the required facilities to complete this study.
Conflict of Interest
There exists no conflict of interest among authors regarding the publication of this book chapter.
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