New Agents for Gastrointestinal Stromal Tumors

  • Yoichi NaitoEmail author
  • Toshihiko Doi


Gastrointestinal stromal tumors (GISTs) are rare soft tissue sarcomas arising from gastrointestinal tract. Standard of care for metastatic GIST is molecular targeted therapy (imatinib, sunitinib, and regorafenib). Developmental therapeutics for GIST is focused on primary or acquired resistance to these agents. In this section, we discuss new agents for the treatment of GIST.


Developmental therapeutics Gastrointestinal stromal tumor Imatinib resistance 


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of Experimental TherapeuticsNational Cancer Center Hospital EastKashiwaJapan

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