B Vitamins and Ageing

  • Kathleen Mikkelsen
  • Vasso ApostolopoulosEmail author
Part of the Subcellular Biochemistry book series (SCBI, volume 90)


Vitamin B contributes to the overall health and wellbeing, including that of energy metabolism, methylation, synthesis and DNA repair and proper immune function. Deficiency in B vitamins has been linked to neurocognitive disorders, mitochondrial dysfunction, immune dysfunction and inflammatory conditions. In ageing populations B vitamin deficiency has been linked to cardiovascular disorders, cognitive dysfunction, osteoporosis and methylation disorders and can increase the risk of developing degenerative diseases, particularly cardiovascular disease, cognitive diseases and osteoporosis. Optimization of B vitamin status in the elderly may prove beneficial in the prevention of degenerative diseases. Here we discuss broadly the role of B vitamins in ageing.


Vitamin B Ageing Niacin Thiamine Folate Cobalamin Riboflavin Pyridoxine 



VA was supported by the Victoria University College of Health and Biomedicine start-up funds, and KM was supported by the Victoria University Vice-Chancellor’s Scholarship.


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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Institute for Health and SportVictoria UniversityWerribeeAustralia

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