Quorum Sensing and Biofilm Disassembly Process in Pseudomonas aeruginosa, Staphylococcus aureus and Xanthomonas campestris

  • Santosh Kumar Singh


Quorum sensing (QS) is a cooperative activity among bacterial cells that is mediated by extracellular cell signaling biomolecules and regulates multiple social traits like biofilm. Similar to QS, biofilm formation is also a cooperative activity among bacterial cell population that leads to formation of extracellular matrix in which bacterial cells are living embedded. Multiple findings intuitively indicate that QS may regulate biofilm formation when cell density of bacterial populations reaches at threshold levels.

However, a group of studies provide convincing evidences that QS initiates in established biofilm and leads to maturation and dispersion of biofilm. This chapter will explain the emerging concepts that QS regulates biofilm disassembly process using three pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus aureus and Xanthomonas campestris) as example.


Bacteria Biofilm eDNA Quorum sensing Bacterial adhesins 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Santosh Kumar Singh
    • 1
  1. 1.Molecular Biology Unit, Institute of Medical SciencesBanaras Hindu UniversityVaranasiIndia

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