Sclerochoroidal Calcification

  • Tero T. Kivelä
Part of the Retina Atlas book series (RA)


Sclerochoroidal calcification, deposition of calcium pyrophosphate within the sclera with secondary compression and atrophy of the choroid that can mimic a choroidal tumor, especially an osteoma, first appeared in case reports of patients with pseudohypoparathyroidism and hyperparathyroidism between 1979 and 1982 (Wong et al. 1979; Goldstein and Miller 1982). A patient with normal calcium and phosphorous metabolism was first published in 1989 by Lim and Goldberg (Lim and Goldberg 1989) after hearing a talk on another idiopathic case that Jerry Shields delivered at a meeting of the American Academy of Ophthalmology Fluorescein Angiography Club (Lim and Goldberg 1989; Shields and Shields 2002) in 1987; the same year, two cases misdiagnosed as osteomas were published (Wiesner et al. 1987). In 1989, seven patients with idiopathic sclerochoroidal calcification from the Wills Eye Hospital, Northwestern University, and University of Kentucky were reported in the annual meeting of the American Academy of Ophthalmology and published in 1991 by Sivalingam, Shields, Shields, McNamara, Jampol, Wood, and Daubert (Sivalingam et al. 1991), followed in 1992 by a report of 19 patients collected from seven hospitals (Schachat et al. 1992). The latter two papers established sclerochoroidal calcification as an entity: a benign, degenerative, usually bilateral lesion, located in the postequatorial, usually superotemporal fundus of patients who either are elderly or have a systemic abnormality of calcium, phosphorous, or magnesium metabolism. Sclerochoroidal calcification has later been shown to be a scleral lesion with secondary choroidal atrophy (Fung et al. 2013; Hasanreisoglu et al. 2015).


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Tero T. Kivelä
    • 1
  1. 1.Department of OphthalmologyUniversity of Helsinki and Helsinki University HospitalHelsinkiFinland

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