Acute Peritoneal Dialysis (PD)

  • Mignon McCullochEmail author
  • Sidharth Kumar Sethi
  • Ilana Webber
  • Peter Nourse


Peritoneal dialysis for AKI remains an important form of AKI treatment especially in the setting of small infants as well as low- and middle-income countries where extracorporeal facilities may not easily be available. The gold standard is a Tenckhoff catheter placed by a surgeon with training in this area in a sterile environment and then commencing automated PD using commercially manufactured dialysis fluid. However in many settings this may not be available and so this chapter offers alternative improvisation techniques for bed-side insertion of PD catheters/similar as well as custom produced dialysis fluid in an attempt to offer PD for any child with AKI in the acute setting.


Peritoneal dialysis (PD) Acute kidney injury (AKI) PD catheter Tenckhoff 


  1. 1.
    Susantitaphong P, Cruz D, Cerda J, Abulfaraj M, Alqahtani F, Koulouridis I, Jaber B, Acute Kidney Injury Advisory Group of the American Society of Nephrology. World incidence of AKI: a meta-analysis. Clin J Am Soc Nephrol. 2013;8(9):1482–93.CrossRefGoogle Scholar
  2. 2.
    Hui-Stickle S, Brewer ED, Goldstein SL. Pediatric ARF epidemiology at a tertiary care center from 1999 to 2001. Am J Kidney Dis. 2005;45(1):96–101.CrossRefGoogle Scholar
  3. 3.
    Williams DM, Sreedhar SS, Mickell JJ, Chan JC. Acute kidney failure: a pediatric experience over 20 years. Arch Pediatr Adolesc Med. 2002;156(9):893–900.CrossRefGoogle Scholar
  4. 4.
    Abdelraheem M, Ali E-T, Osman R, Ellidir R, Bushara A, Hussein R, et al. Outcome of acute kidney injury in Sudanese children—an experience from a sub-Saharan African unit. Perit Dial Int. 2014;34(5):526–33.CrossRefGoogle Scholar
  5. 5.
    Esezobor CI, Ladapo TA, Lesi FE. Peritoneal dialysis for children with acute kidney injury in Lagos, Nigeria: experience with adaptations. Perit Dial Int. 2014;34(5):534–8.CrossRefGoogle Scholar
  6. 6.
    Olowu WA, Niang A, Osafo C, Ashuntantang G, Arogundade FA, Porter J, et al. Outcomes of acute kidney injury in children and adults in sub-Saharan Africa: a systematic review. Lancet Glob Health. 2016;4(4):e242–50. Scholar
  7. 7.
    Cerda J, Bagga A, Kher V, Chakravarthi RM. The contrasting characteristics of acute kidney injury in developed and developing countries. Nat Clin Pract Nephrol. 2008;4(3):138–53. Scholar
  8. 8.
    Flynn JT, Kershaw DB, Smoyer WE, Brophy PD, McBryde KD, Bunchman TE. Peritoneal dialysis for management of pediatric acute renal failure. Perit Dial Int. 2001;21(4):390–4.PubMedGoogle Scholar
  9. 9.
    Reznik VM, Randolph G, Collins CM, Peterson BM, Lemire JM, Mendoza SA. Cost analysis of dialysis modalities for pediatric acute renal failure. Perit Dial Int. 1993;13(4):311–3.PubMedGoogle Scholar
  10. 10.
    Flynn JT. Choice of dialysis modality for management of pediatric acute renal failure. Pediatr Nephrol. 2002;17(1):61–9. Scholar
  11. 11.
    Auron A, Warady BA, Simon S, Blowey DL, Srivastava T, Musharaf G, Alon US. Use of the multipurpose drainage catheter for the provision of acute peritoneal dialysis in infants and children. Am J Kidney Dis. 2007;49(5):650–5. Scholar
  12. 12.
    Bunchman T, Smoyer W, Valentini R, Kershaw D, Gregory M, Sedman A. Modality and mortality in pediatric renal replacement therapy. Paper presented at the Journal of the American Society of Nephrology. 1994.Google Scholar
  13. 13.
    Chionh CY, Soni SS, Finkelstein FO, Ronco C, Cruz DN. Use of peritoneal dialysis in AKI: a systematic review. Clin J Am Soc Nephrol. 2013;8(10):1649–60. Scholar
  14. 14.
    Cullis B, Abdelraheem M, Abrahams G, Balbi A, Cruz DN, Frishberg Y, Koch V, McCulloch M, Numanoglu A, Nourse P, Pecoits-Filho R, Ponce D, Warady B, Yeates K, Finkelstein FO. ISPD Guidelines/Recommendations. Peritoneal dialysis for acute kidney injury. Perit Dial Int. 2014;34:494–517.CrossRefGoogle Scholar
  15. 15.
    Bai ZG, Yang K, Tian JH, Ma B, Liu Y, Jiang L, et al. Bicarbonate versus lactate solutions for acute peritoneal dialysis. Cochrane Database Syst Rev. 2014;7:CD007034. Scholar
  16. 16.
    Ponce D, Balbi AL, Amerling R. Advances in peritoneal dialysis in acute kidney injury. Blood Purif. 2012;34(2):107–16. Scholar
  17. 17.
    Olszewski, AE, Stein, D, McCulloch, M, Su, S, Hames, D, Wolbrink, TA. Virtual Peritoneal Dialysis Simulator. 2016. Online Interactive Simulator OPENPediatrics
  18. 18.
    Warady BA, Bakkaloglu S, Newland J, Cantwell M, Verrina E, Neu A, et al. Consensus guidelines for the prevention and treatment of catheter-related infections and peritonitis in pediatric patients receiving peritoneal dialysis: 2012 update. Perit Dial Int. 2012;32(Suppl 2):S32–86. Scholar
  19. 19.
    Hisamatsu C, Maeda K, Aida Y, Yasufuku M, Ninchoji T, Kaito H, et al. A novel technique of catheter placement with fibrin glue to prevent pericatheter leakage and to enable no break-in period in peritoneal dialysis. J Pediatr Urol. 2015;11(5):299–300. Scholar
  20. 20.
    Fischbach M, Zaloszyc A, Schaefer B, Schmitt CP. Should sodium removal in peritoneal dialysis be estimated from the ultrafiltration volume? Pediatr Nephrol. 2016;32(3):419–24. Scholar
  21. 21.
    Bunchman TE, Meldrum MK, Meliones JE, Sedman AB, Walters MB, Kershaw DB. Pulmonary function variation in ventilator dependent critically ill infants on peritoneal dialysis. Adv Perit Dial. 1992;8:75–8.PubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Mignon McCulloch
    • 1
    Email author
  • Sidharth Kumar Sethi
    • 2
    • 3
  • Ilana Webber
    • 4
  • Peter Nourse
    • 4
  1. 1.Paediatric Nephrology and Paediatric ICURed Cross Children’s HospitalCape TownSouth Africa
  2. 2.Pediatric Nephrology and Pediatric Kidney Transplantation, Kidney and Urology InstituteMedanta, The Medicity HospitalGurgaonIndia
  3. 3.SecretaryIndian Society of Pediatric NephrologyNew DelhiIndia
  4. 4.Paediatric Renal Unit, Red Cross Children’s HospitalUniversity of Cape TownCape TownSouth Africa

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