Acute Kidney Injury: Definitions and Epidemiology

  • Neziha Celebi
  • Ayse Akcan ArikanEmail author


Acute kidney injury (AKI) could be community acquired or hospital acquired and is ubiquitous in the pediatric population, affecting one in three hospitalized children. Critically ill patients have the highest risk factors for AKI development and suffer severe consequences including increased mortality and new disability. Definition of AKI can impact detection and adjudication, and severity determines outcomes. Here, we review the current available AKI definitions, highlighting inherent differences. Then we provide a brief overview of the diagnostic approach to AKI in the pediatric intensive care unit.


Acute kidney injury Children Acute tubular necrosis AKI ATN 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of Pediatrics, Renal SectionBaylor College of MedicineHoustonUSA
  2. 2.Department of Pediatrics, Critical Care SectionBaylor College of MedicineHoustonUSA
  3. 3.Critical Care NephrologyTexas Children’s HospitalHoustonUSA

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