Understanding Diabetes: Uncovering the Leads from Ayurveda

  • Sanjeev Rastogi


Diabetes is observed as a pandemic upsurge in recent decades. It is proposed to become the world’s biggest cause of impending deaths in the future. Diabetes is found to have a variability of distribution in various geographical areas having a few areas affected heavily while sparing others. India is among the few countries worst hit by diabetes sharing a substantial sum in total global diabetic population. Ironically India has a pluralistic model of health care in existence since long where a number of alternative therapies including Ayurveda are available to be practiced. This is obvious to speculate that in Indian context, such pluralism of health care should have added value to the conventional health care in the areas where this alone has not been found to offer optimal care. Unfortunately, despite highly illustrious descriptions of diabetes in Ayurveda, the knowledge had not efficiently been utilized by its caregivers. We present here some novel and yet unexplored areas where inputs from Ayurveda may bring a paradigm shift in diabetes understanding in terms of its early clinical diagnosis, management, and complication prevention. This further illustrates a high translational value of some Ayurvedic concepts referring to diabetes in contemporary sense. The same seems highly desired in India if our current understanding of diabetes is needed to be brought to the next level of care.


Diabetes prevention Diabetes diagnosis Diabetes etiology Diabetes management Ayurveda 


  1. 1.
    NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet. 2016;387(10027):1513–30.CrossRefGoogle Scholar
  2. 2.
    Jia W. Diabetes research in China: making progress. Lancet Diabetes Endocrinol. 2017;5(1):9–10.CrossRefGoogle Scholar
  3. 3.
    WHO Global report of Diabetes 2016.Google Scholar
  4. 4.
    Arunachalam S, Gunasekaran S. Diabetes research in India and China today: from literature-based mapping to health-care policy. Curr Sci. 2002;82(9):1086–97.Google Scholar
  5. 5.
    Ratnakar A, Satyanarayan K. Diabetes research In India: a citation profile. Indian J Med Res. 2007;125:483–7.PubMedGoogle Scholar
  6. 6.
    Why m Diabetes. Http://Mdiabetes.Nhp.Gov.In/. Last downloaded on 20 Sep 2016.
  7. 7.
    Modak M, Dixit P, Londhe J, Ghaskadbi S, Paul T, Devasagayam A. Indian herbs and herbal drugs used for the treatment of diabetes. J Clin Biochem Nutr. 2007;40:163–73.CrossRefGoogle Scholar
  8. 8.
    Ayurvedic interventions for diabetes mellitus: a systematic review. Summary, evidence report/technology assessment: number 41. AHRQ Publication No. 01-E039, June 2001.Google Scholar
  9. 9.
    Ayush Research Portal.Google Scholar
  10. 10.
  11. 11.
    Patwardhan B. Ayurvedic drugs in case: claims, evidence, regulations and ethics. J Ayurveda Integr Med. 2016;7(3):135–7.CrossRefGoogle Scholar
  12. 12.
    Guidance for industry-diabetes mellitus: developing drugs and therapeutic biologics for treatment and prevention. Last accessed on 20 Jan 2017.
  13. 13.
    Islam T, Rahman A, Islam AU. Effects of aqueous extract of fresh leaves of Abroma augusta L. on oral absorption of glucose and metformin hydrochloride in experimental rats. ISRN Pharm. 2012;2012:472586. Scholar
  14. 14.
    Ayurvedline. Ayurvedic drug index. 11th ed. Bangalore: 2010. p. 471–78.Google Scholar
  15. 15.
    Rajput DS, Patgiri BJ, Galib R, Prajapati PK. Anti-diabetic formulations of Nāga bhasma (lead calx): a brief review. Ancient Sci Life. 2013;33(1):52–9.CrossRefGoogle Scholar
  16. 16.
    Guntaru KS, Nagarajan P, Mcphedran P, Goodman TR, Hodsdon ME, Strout MP. Ayurvedic herbal medicine and lead poisoning. J Hematol Oncol. 2011;4:51.CrossRefGoogle Scholar
  17. 17.
    Parivallal T, Anjana RM, Mohan V. Frequency of use of Indian systems of Medicine and homeopathy among diabetic patients in Chennai (CURES-80). J Social Health Diabetes. 2015;3(2):125.CrossRefGoogle Scholar
  18. 18.
    Mac Lean CD, Littenberg B, Kennedy AG. Limitations of diabetes pharmacotherapy: results from the Vermont Diabetes Information System study. BMC Fam Pract. 2006;7:50.CrossRefGoogle Scholar
  19. 19.
    Ritz E. Limitations and future treatment options in type 2 diabetes with renal impairment. Diabetes Care. 2011;34(Suppl 2):S330–4.CrossRefGoogle Scholar
  20. 20.
    Sohal T, Sohal P, King Shier KM, Khan NA. Barriers and facilitators for type-2 diabetes management in South Asians: a systematic review. PLoS One. 2015;10(9):e0136202.CrossRefGoogle Scholar
  21. 21.
    Banerjee S, Debnath P, Rao PN, Tripathy TB, Adhikari A, Debnath PK. Ayurveda in changing scenario of diabetes management for developing safe and effective treatment choices for the future. J Comp Integr Med. 2015;12(2):101–10.Google Scholar
  22. 22.
    Janket S, Manson JE, Sesso H, Buring JE, Liu S. A prospective study of sugar intake and risk of type 2 diabetes in women. Diabetes Care. 2003;26(4):1008–15.CrossRefGoogle Scholar
  23. 23.
    Marsden J, Pickering D. Urine testing for diabetic analysis. Community Eye Health. 2015;28(92):77.PubMedPubMedCentralGoogle Scholar
  24. 24.
    Chowta NK, Pant P, Chowta MN. Microalbuminuria in diabetes mellitus: association with age, sex, weight, and creatinine clearance. Indian J Nephrol. 2009;19(2):53–6.CrossRefGoogle Scholar
  25. 25.
    Marunaka Y. Roles of interstitial fluid pH in diabetes mellitus: Glycolysis and mitochondrial function. World J Diabetes. 2015;6(1):125–35.CrossRefGoogle Scholar
  26. 26.
    Hansen T. Type 2 diabetes mellitus—a multifactorial disease. Ann Univ Mariae Curie Sklodowska Med. 2002;57(1):544–9.PubMedGoogle Scholar
  27. 27.
    Faerch K, Hulmán A, Solomon TP. Heterogeneity of pre-diabetes and type 2 diabetes: implications for prediction, prevention and treatment responsiveness. Curr Diabetes Rev. 2016;12(1):30–41.CrossRefGoogle Scholar
  28. 28.
    Tuomi T, Santoro N, Caprio S, Cai M, Weng J, Groop L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet. 2014;383(9922):1084–94. doi: Epub 2013 Dec 3.
  29. 29.
    Jurysta C, Bulur N, Oguzhan B, et al. Salivary glucose concentration and excretion in normal and diabetic subjects. J Biomed Biotechnol. 2009; 2009, Article ID 430426, 6 pages. CrossRefGoogle Scholar
  30. 30.
    Kumar S, Padmashree S, Jayalekshmi R. Correlation of salivary glucose, blood glucose and oral candidal carriage in the saliva of type 2 diabetics: a case-control study. Contemp Clin Dentist. 2014;5(3):312–7. Scholar
  31. 31.
    Møller N, Jørgensen JOL. Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr Rev. 2009;30(2):152–77. Scholar
  32. 32.
    Glycated nail protein suitability for diabetes testing.
  33. 33.
    Mata AD, Marques D, Rocha S, Francisco H, Santos C, Mesquita MF, Singh J. Effects of diabetes mellitus on salivary secretion and its composition in the human. Mol Cell Biochem. 2004;261(1–2):137–42.CrossRefGoogle Scholar
  34. 34.
    Kenny GP, Sigal RJ, McGinn R. Body temperature regulation in diabetes. Temp Multidiscip Biomed J. 2016;3(1):119–45. Scholar
  35. 35.
    Moyer J, Wilson DF, inkelshtein I, Wong B, Potts R. Correlation between sweat glucose and blood glucose in subjects with diabetes. Diabetes Technol Ther. 2012;14(5):398–402. doi: Epub 2012 Feb 29.CrossRefGoogle Scholar
  36. 36.
    Jadoon S, Karim S, Akram MR, et al. Recent developments in sweat analysis and its applications. Int J Anal Chem. 2015; 2015: Article ID 164974, 7 pages. Scholar
  37. 37.
    Grice EA, Segre JA. The skin microbiome. Nat Rev Microbiol. 2011;9(4):244–53. Scholar
  38. 38.
    Stokes A, Preston SH. Deaths attributable to diabetes in the United States: comparison of data sources and estimation approaches. PLoS One. 2017;12(1):e0170219. Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Sanjeev Rastogi
    • 1
  1. 1.Department of Kaya ChikitsaState Ayurvedic College and Hospital, Lucknow UniversityLucknowIndia

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