Post-Stroke Treatment Strategies, Management, and Rehabilitation: Where We Stand?

  • Mallikarjuna Rao Gedda
  • Surya Prakash Pandey
  • Kulsoom Zahra
  • Prasoon Madhukar
  • Abhishek Pathak


Stroke is a medical condition occurring due to the deprivation of blood supply temporarily/permanently to specific area of the brain leading to hypoxia to the brain cells, which eventually causes mortality of the patients. Stroke is categorized into three different types, i.e., transient ischemic attack (shows stroke-like symptoms), acute ischemic strokes (hiccups, nausea, troubles in walking and speaking, numbness of the face, arm, and leg mainly on one side of the body), and hemorrhagic strokes (loss of consciousness and balance, nausea, vomiting, seizures, dizziness). Over the past 20 years, the inhospital and post-discharge management for stroke has been deeply transformed. Their early detection and inhospital therapies can deteriorate short- and long-term outcomes of strokes. Inhospital treatments include thrombolysis, aspirin treatment, antithrombotic therapy, therapeutic hypothermia, blood pressure management, antiplatelet strategies, and surgery for cerebral edema. There are several important aspects which are discussed below in this chapter that should be taken care in order to decrease mortality rate in stroke patients.


Stroke Acute ischemic strokes Transient ischemic attack Cerebral edema Treatments 



Arachidonic acid


Angiotensin-converting enzyme


Adenosine diphosphate


Atrial fibrillation


Acute ischemic strokes


Antiplatelet agent


Amyloid precursor protein


American Stroke Association


Blood-brain barrier


Blood pressure


Cyclic adenosine monophosphate


Cerebral blood flow


Central nervous system




Cerebrospinal fluid


Dual antiplatelet therapy




Hemorrhagic strokes




Myocardial infarction


Novel oral anticoagulants




Prolyse in acute cerebral thromboembolism II


Reactive nitrogen species


Reactive oxygen species


Recombinant tissue plasminogen activator


Thromboxane A2


Traditional Chinese medicine


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Mallikarjuna Rao Gedda
    • 1
  • Surya Prakash Pandey
    • 2
  • Kulsoom Zahra
    • 1
  • Prasoon Madhukar
    • 2
  • Abhishek Pathak
    • 3
  1. 1.Department of Biochemistry, Institute of ScienceBanaras Hindu UniversityVaranasiIndia
  2. 2.Department of Zoology, Institute of ScienceBanaras Hindu UniversityVaranasiIndia
  3. 3.Department of Neurology, Institute of Medical SciencesBanaras Hindu UniversityVaranasiIndia

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