Biomechanical Optimization-Based Planning of Periacetabular Osteotomy

  • Li Liu
  • Klaus Siebenrock
  • Lutz-P. Nolte
  • Guoyan Zheng
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1093)


Modern computerized planning tools for periacetabular osteotomy (PAO) use either morphology-based or biomechanics-based methods. The latter rely on estimation of peak contact pressures and contact areas using either patient-specific or constant thickness cartilage models. We performed a finite element analysis investigating the optimal reorientation of the acetabulum in PAO surgery based on simulated joint contact pressures and contact areas using patient-specific cartilage model. Furthermore we investigated the influences of using patient-specific cartilage model or constant thickness cartilage model on the biomechanical simulation results. Ten specimens with hip dysplasia were used in this study. Image data were available from CT arthrography studies. Bone models were reconstructed. Mesh models for the patient-specific cartilage were defined and subsequently loaded under previously reported boundary and loading conditions. Peak contact pressures and contact areas were estimated in the original position. Afterward we used validated preoperative planning software to change the acetabular inclination by an increment of 5° and measured the lateral center-edge angle (LCE) at each reorientation position. The position with the largest contact area and the lowest peak contact pressure was defined as the optimal position. In order to investigate the influence of using patient-specific cartilage model or constant thickness cartilage model on the biomechanical simulation results, the same procedure was repeated with the same bone models but with a cartilage mesh of constant thickness. Comparison of the peak contact pressures and the contact areas between these two different cartilage models showed that good correlation between these two cartilage models for peak contact pressures (r = 0.634 ∈[0.6, 0.8], p < 0.001) and contact areas (r = 0.872 > 0.8, p < 0.001). For both cartilage models, the largest contact areas and the lowest peak pressures were found at the same position. Our study is the first study comparing peak contact pressures and contact areas between patient-specific and constant thickness cartilage models during PAO planning. Good correlation for these two models was detected. Computer-assisted planning with FE modeling using constant thickness cartilage models might be a promising PAO planning tool when a conventional CT is available.


Hip dysplasia Periacetabular osteotomy (PAO) Planning Biomechanical simulation Finite element analysis (FEA) Image-guided surgery Joint preservation surgery 



This work was supported by the open source dysplastic hips image data from the University of Utah [17] and partially supported by Natural Science Foundation of SZU (grant no. 2017089) and Japanese-Swiss Science and Technology Cooperation Program.

This chapter was modified from the paper published by our group in PLoS One (Li et al., PLoS One 2016; 11(1):e0146452). The related contents were reused with permission.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Li Liu
    • 1
    • 2
  • Klaus Siebenrock
    • 3
  • Lutz-P. Nolte
    • 2
  • Guoyan Zheng
    • 2
  1. 1.National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science CenterShenzhen UniversityShenzhenChina
  2. 2.Institute for Surgical Technology and BiomechanicsUniversity of BernBernSwitzerland
  3. 3.Department of Orthopedic Surgery, InselspitalUniversity of BernBernSwitzerland

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