Acute Liver Failure in Children: Intensive Care Management Protocol

  • Naresh Shanmugam
  • Anil DhawanEmail author


The practical definition of acute liver failure (ALF) suggested by the Pediatric Acute Liver Failure study group is “coagulopathy with INR ≥ 1.5 with encephalopathy or INR ≥ 2 without encephalopathy due to a liver cause, not correctable by intravenous vitamin K, along with biochemical evidence of acute liver injury.”

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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of Paediatric Liver, GI and NutritionInstitute of Advanced Paediatrics, Dr. Rela Institute and Medical CentreChennaiIndia
  2. 2.Paediatric Liver GI and Nutrition Center and MowatLabsKing’s College HospitalLondonUK

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