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The Human Sexual Response

  • Shah Dupesh Khan
  • Karthik Gunasekaran
Chapter

Abstract

Sex remains highly controversial and is a major driving force for the human brain [1]. The brain is the master seat control for all sexual behaviour. Human beings are sexual through a better part of their entire lives [1]. Sexuality of humans manifests in different ways with increasing age. Despite the controversies that surround human sex, for a majority of us, sex is a highly pleasurable process [2]. In the boarder context things, good sexual health definitely goes hand in hand with general wellness and good health [2]. But why engage in sex in the first place? Sex is definitely more wasteful compared to asexual modalities of reproduction [3]. Moreover sex and sexual reproduction are far less efficient in propagating a species as compared to asexual reproduction [3]. The exact answer however has eluded researchers for years despite excellent studies on animal sexual behaviour.

References

  1. 1.
    DeLamater J, Friedrich WN. Human sexual development. J Sex Res. 2002;39(1):10–4.CrossRefGoogle Scholar
  2. 2.
    Jannini EA, Fisher WA, Bitzer J, McMahon CG. Is sex just fun? How sexual activity improves health. J Sex Med. 2009;6:2640–8.CrossRefGoogle Scholar
  3. 3.
    Morran LT, Schmidt OG, Gelarden IA, Parris RC II, Lively CM. Running with the red queen: host–parasite coevolution selects for biparental sex. Science. 2011;333:216–8.CrossRefGoogle Scholar
  4. 4.
    Meston CM, Buss DM. Why humans have sex. Arch Sex Behav. 2007;36:477–507.CrossRefGoogle Scholar
  5. 5.
    Meston CM, Hamilton LD, Harte CB. Sexual motivation in women as a function of age. J Sex Med. 2009;6:3305–19.CrossRefGoogle Scholar
  6. 6.
    Georgiadis JR, Kringelbach ML. The human sexual response cycle: brain imaging evidence linking sex to other pleasures. Prog Neurobiol. 2012;98(1):49–81.CrossRefGoogle Scholar
  7. 7.
    Pfaus JG, Kippin TE, Coria-Avila G. What can animal models tell us about human sexual response? Ann Rev Sex Res. 2003;14(1):1–63.Google Scholar
  8. 8.
    Feiring C, Cleland CM, Simon VA. Abuse-specific self-schemas and self functioning: a prospective study of sexually abused youth. J Clin Child Adolesc Psychol. 2010;39:35–50.CrossRefGoogle Scholar
  9. 9.
    Ferretti A, Caulo M, Del Gratta C, Di Matteo R, Merla A, Montorsi F, Pizzella V, Pompa P, Rigatti P, Rossini PM, Salonia A, Tartaro A, Romani GL. Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI. NeuroImage. 2005;26:1086–96.CrossRefGoogle Scholar
  10. 10.
    Rizzolatti G, Craighero L. The mirror-neuron system. Annu Rev Neurosci. 2004;27:169–92.CrossRefGoogle Scholar
  11. 11.
    Moulier V, Mouras H, Pelegrini-Issac M, Glutron D, Rouxel R, Grandjean B, Bittoun J, Stoleru S. Neuroanatomical correlates of penile erection evoked by photographic stimuli in human males. NeuroImage. 2006;33:689–99.CrossRefGoogle Scholar
  12. 12.
    Mouras H, Stoleru S, Moulier V, Pelegrini-Issac M, Rouxel R, Grandjean B, Glutron D, Bittoun J. Activation of mirror-neuron system by erotic video clips predicts degree of induced erection: an fMRI study. NeuroImage. 2008;42:1142–50.CrossRefGoogle Scholar
  13. 13.
    Ponseti J, Bosinski HA, Wolff S, Peller M, Jansen O, Mehdorn HM, Buchel C, Siebner HR. A functional endophenotype for sexual orientation in humans. NeuroImage. 2006;33:825–33.CrossRefGoogle Scholar
  14. 14.
    Martinson FM. The sexual life of children. Westport, CT: Bergin and Garvey; 1994.Google Scholar
  15. 15.
    Bull JJ. Evolution of sex determining mechanisms. Menlo Park: The Benjamin/Cummings Publishing Company; 1983.Google Scholar
  16. 16.
    Masters WH, Johnson VE. Human sexual response. Boston, MA: Little, Brown & Company; 1966.Google Scholar
  17. 17.
    Robinson P. The modernization of sex. New York: Harper and Row; 1976.Google Scholar
  18. 18.
    Beach FA. Characteristics of masculine “sex drive”. In: Jones MR, editor. Nebraska symposium on motivation. Lincoln: University of Nebraska Press; 1956. p. 1–32.Google Scholar
  19. 19.
    Kinsey AC, Pomeroy WB, Martln CE, Gebhard PH. Sexual behavior in the human female. Philadelphia: W. B. Saunders Co; 1953.Google Scholar
  20. 20.
    Hackett G. The use of questionnaires to assess sexual function. Trends Urol Mens Health. 2017;8(1):17–20.CrossRefGoogle Scholar
  21. 21.
    Basson R. Human sex-response cycles. J Sex Marital Ther. 2001;27:33–43.CrossRefGoogle Scholar
  22. 22.
    Janssen E, Everaerd W, Spiering M, et al. Automatic processes and the appraisal of sexual stimuli: toward an information processing model of sexual arousal. J Sex Res. 2000;37:8–23.CrossRefGoogle Scholar
  23. 23.
    Laan E, van Driel EM, van Lunsen RHW. Genital responsiveness in healthy women with and without sexual arousal disorder. J Sex Med. 2008;5:1424–35.CrossRefGoogle Scholar
  24. 24.
    Goldhammer DL, McCabe MP. A qualitative exploration of the meaning and experience of sexual desire among partnered women. Can J Hum Sex. 2011;20(1–2):19–34.Google Scholar
  25. 25.
    Vannier SA, O’Sullivan LF. Sex without desire: characteristics of occasions of sexual compliance in young adults’ committed relationships. J Sex Res. 2010;47:429–39.CrossRefGoogle Scholar
  26. 26.
    Stole’ru S, Fonteille V, Corne’lis C, et al. Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: a review and meta-analysis. Neurosci Biobehav Rev. 2012;36:1481–509.CrossRefGoogle Scholar
  27. 27.
    American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5®). San Francisco: American Psychiatric Publishing; 2013. p. 22.CrossRefGoogle Scholar
  28. 28.
    King M, Holt V, Nazareth I. Women’s view of their sexual difficulties: agreement and disagreement for the clinical diagnoses. Arch Sex Behav. 2007;36:281–8.CrossRefGoogle Scholar
  29. 29.
    Levin RJ. The human sexual response cycle. In: The textbook of clinical sexual medicine. Cham: Springer; 2017. p. 39–51.CrossRefGoogle Scholar
  30. 30.
    Havermans RC. How to tell where ‘liking’ ends and ‘wanting’ begins. Appetite. 2012;58:252–5.CrossRefGoogle Scholar
  31. 31.
    Smith KS, Berridge KC, Aldridge JW. Disentangling pleasure from incentive salience and learning signals in brain reward circuitry. Proc Natl Acad Sci U S A. 2011;108:E255–64.CrossRefGoogle Scholar
  32. 32.
    Mostafa T, El Khouly G, Hassan A. Pheromones in sex and reproduction: do they have a role in humans? J Adv Res. 2012;3:1–9.CrossRefGoogle Scholar
  33. 33.
    Loken LS, Wessberg J, Morrison I, McGlone F, Olausson H. Coding of pleasant touch by unmyelinated afferents in humans. Nat Neurosci. 2009;12:547–8.CrossRefGoogle Scholar
  34. 34.
    Michels L, Mehnert U, Boy S, Schurch B, Kollias S. The somatosensory representation of the human clitoris: an fMRI study. NeuroImage. 2010;49:177–84.CrossRefGoogle Scholar
  35. 35.
    Georgiadis JR, Reinders AA, Paans AM, Renken R, Kortekaas R. Men versus women on sexual brain function: prominent differences during tactile genital stimulation but not during orgasm. Hum Brain Mapp. 2009;30:3089–101.CrossRefGoogle Scholar
  36. 36.
    Miyagawa Y, Tsujimura A, Fujita K, Matsuoka Y, Takahashi T, Takao T, Takada S, Matsumiya K, Osaki Y, Takasawa M, Oku N, Hatazawa J, Kaneko S, Okuyama A. Differential brain processing of audiovisual sexual stimuli in men: comparative positron emission tomography study of the initiation and maintenance of penile erection during sexual arousal. NeuroImage. 2007;36:830–42.CrossRefGoogle Scholar
  37. 37.
    Ghazanfar AA, Santos LR. Primate brains in the wild: the sensory bases for social interactions. Nat Rev Neurosci. 2004;5:603–16.CrossRefGoogle Scholar
  38. 38.
    Childress AR, Ehrman RN, Wang Z, Li Y, Sciortino N, Hakun J, Jens W, Suh J, Listerud J, Marquez K, Franklin T, Langleben D, Detre J, O’Brien CP. Prelude to passion: limbic activation by unseen drug and sexual cues. PLoS One. 2008;3:e1506.CrossRefGoogle Scholar
  39. 39.
    Rupp HA, Wallen K. Sex differences in response to visual sexual stimuli: a review. Arch Sex Behav. 2008;37:206–18.CrossRefGoogle Scholar
  40. 40.
    Caspers S, Zilles K, Laird AR, Eickhoff SB. ALE meta-analysis of action observation and imitation in the human brain. NeuroImage. 2010;50:1148–67.CrossRefGoogle Scholar
  41. 41.
    Buhler M, Vollstadt-Klein S, Klemen J, Smolka MN. Does erotic stimulus presentation design affect brain activation patterns? Event-related vs blocked fMRI designs. Behav Brain Funct. 2008;4:30.CrossRefGoogle Scholar
  42. 42.
    Klucken T, Schweckendiek J, Merz CJ, Tabbert K, Walter B, Kagerer S, Vaitl D, Stark R. Neural activations of the acquisition of conditioned sexual arousal: effects of contingency awareness and sex. J Sex Med. 2009;6:3071–85.CrossRefGoogle Scholar
  43. 43.
    Savic I, Lindstrom P. PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects. Proc Natl Acad Sci U S A. 2008;105:9403–8.CrossRefGoogle Scholar
  44. 44.
    Clayton AH, Clavet GJ, McGarvey EL, Warnock JK, Weiss K. Assessment of sexual functioning during the menstrual cycle. J Sex Marital Ther. 1999;25:281–91.CrossRefGoogle Scholar
  45. 45.
    Mass R, Holldorfer M, Moll B, Bauer R, Wolf K. Why we haven’t died out yet: changes in women’s mimic reactions to visual erotic stimuli during their menstrual cycles. Horm Behav. 2009;55:267–71.CrossRefGoogle Scholar
  46. 46.
    Chivers ML, Seto MC, Blanchard R. Gender and sexual orientation differences in sexual response to sexual activities versus gender of actors in sexual films. J Pers Soc Psychol. 2007;93:1108–21.CrossRefGoogle Scholar
  47. 47.
    Graham CA. The DSM diagnostic criteria for female sexual arousal disorder. Arch Sex Behav. 2010;39(2):240–55.CrossRefGoogle Scholar
  48. 48.
    Dennerstein L, Lehert P, Guthrie J. The effects of the menopausal transition and biopsychosocial factors on well-being. Arch Womens Ment Health. 2002;5:15–22.CrossRefGoogle Scholar
  49. 49.
    Mah K, Binik YM. The nature of human orgasm: a critical review of major trends. Clin Psychol Rev. 2001;21:823–56.CrossRefGoogle Scholar
  50. 50.
    Warneke LB. A case of temporal lobe epilepsy with an orgasmic component. Can Psychiatr Assoc J. 1976;21(5):319–24.CrossRefGoogle Scholar
  51. 51.
    Georgiadis JR, Kortekaas R, Kuipers R, Nieuwenburg A, Pruim J, Reinders AATS, Holstege G. Regional cerebral blood flow changes associated with clitorally induced orgasm in healthy women. Eur J Neurosci. 2006;24:3305–16.CrossRefGoogle Scholar
  52. 52.
    Georgiadis JR, Reinders AA, van der Graaf FH, Paans AM, Kortekaas R. Brain activation during human male ejaculation revisited. Neuroreport. 2007;18:553–7.CrossRefGoogle Scholar
  53. 53.
    Levin RJ. Revisiting post-ejaculation refractory time-what we know and what we do not know in males and in females. J Sex Med. 2009;6:2376–89.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Shah Dupesh Khan
    • 1
  • Karthik Gunasekaran
    • 1
  1. 1.The Metromale Clinic and Fertility CenterChennaiIndia

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