Gastric cancer remains one of the most common cancers in the world, being the third most common cause of cancer death and the fifth most common malignancy. Incidence rate of gastric cancer is highest in East Asia including Japan, Korea, and China. More than half of new gastric cancer cases in the world have been diagnosed in East Asia. Gastric cancer is not a disease of the past in Japan like other developed Western countries. Although mortality and morbidity rates of gastric cancer have been dramatically declining in Japan, the absolute number of gastric cancer deaths has remained constant for a few decades. The number of deaths has begun to decline in recent years. Interestingly, gastric cancers detected in Japan have characteristic features. Mortality rates in Japan are considerably lower than incidence rates due to the impact of diagnosis and treatment of early-stage gastric cancers.
KeywordsGastric cancer Early gastric cancer Mortality Morbidity H. pylori Salt Diet Atrophy Intestinal metaplasia
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