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Pathology of Ovary: Germ Cell Tumours

  • Pranab Dey
Chapter

Abstract

In this chapter the various germ cell tumours of ovary are described with illustrations of gross and histopathological features. Epidemiology, clinical features, gross features, histopathology, immunohistochemistry, molecular genetics, differential diagnosis and treatment with prognosis of these tumours are also discussed.

Keywords

Dysgerminoma Yolk sac tumour Schiller Duval bodies Mature cystic teratoma Immature teratoma Peritoneal gliomatosis Struma ovarii Mixed germ cell tumours Insular carcinoid 

Reference

  1. 1.
    Kurman RJ, Carcangiu ML, Herrington S, Young RH. WHO classification of tumours of female genital reproductive organs. 4th ed. Lyon: International Agency for Research on Cancer; 2014.Google Scholar

Suggested Reading

  1. Alwazzan AB, Popowich S, Dean E, Robinson C, Lotocki R, Altman AD. Pure immature teratoma of the ovary in adults: thirty-year experience of a single tertiary care center. Int J Gynecol Cancer. 2015;25(9):1616–22.CrossRefGoogle Scholar
  2. Aslam MF, Choi C, Khulpateea N. Neuroendocrine tumour of the ovary. J Obstet Gynaecol. 2009;29(5):449–51.CrossRefGoogle Scholar
  3. Ayhan A, Aksu T, Selçuk Tuncer Z, Mercan R, Ozbay G. Immature teratoma of the ovary. Eur J Gynaecol Oncol. 1993;14(3):205–7.PubMedGoogle Scholar
  4. Corakçi A, Ozeren S, Ozkan S, Gürbüz Y, Ustün H, Yücesoy I. Pure nongestational choriocarcinoma of ovary. Arch Gynecol Obstet. 2005;271(2):176–7.CrossRefGoogle Scholar
  5. Dällenbach P, Bonnefoi H, Pelte MF, Vlastos G. Yolk sac tumours of the ovary: an update. Eur J Surg Oncol. 2006;32(10):1063–75.CrossRefGoogle Scholar
  6. Fukunaga M, Endo Y, Miyazawa Y, Ushigome S. Small cell neuroendocrine carcinoma of the ovary. Virchows Arch. 1997;430(4):343–8.CrossRefGoogle Scholar
  7. Gallion H, van Nagell JR Jr, Donaldson ES, Hanson MB, Powell DF. Immature teratoma of the ovary. Am J Obstet Gynecol. 1983;146(4):361–5.CrossRefGoogle Scholar
  8. Gershenson DM. Update on malignant ovarian germ cell tumours. Cancer (Phila). 1993;71:1581–90.CrossRefGoogle Scholar
  9. Goffredo P, Sawka AM, Pura J, Adam MA, Roman SA, Sosa JA. Malignant struma ovarii: a population-level analysis of a large series of 68 patients. Thyroid. 2015;25(2):211–5.CrossRefGoogle Scholar
  10. Goyal LD, Kaur S, Kawatra K. Malignant mixed germ cell tumour of ovary--an unusual combination and review of literature. J Ovarian Res. 2014;7:91.CrossRefGoogle Scholar
  11. Guillem V, Poveda A. Germ cell tumours of the ovary. Clin Transl Oncol. 2007;9(4):237–43.CrossRefGoogle Scholar
  12. Monti E, Mortara L, Zupo S, Dono M, Minuto F, Truini M, Naseri M, Giusti M. Papillary thyroid cancer in a struma ovarii: a report of a rare case. Hormones (Athens). 2015;14(1):154–9.Google Scholar
  13. Nogales FF, Dulcey I, Preda O. Germ cell tumours of the ovary: an update. Arch Pathol Lab Med. 2014;138(3):351–62.CrossRefGoogle Scholar
  14. Nogales FF, Preda O, Nicolae A. Yolk sac tumours revisited. A review of their many faces and names. Histopathology. 2012;60(7):1023–33.CrossRefGoogle Scholar
  15. Tsuji T, Togami S, Shintomo N, Fukamachi N, Douchi T, Taguchi S. Ovarian large cell neuroendocrine carcinoma. J Obstet Gynaecol Res. 2008;34(4 Pt 2):726–30.CrossRefGoogle Scholar
  16. Wang Y, Zhou F, Qian Z, Qing J, Zhao M, Huang L. Mixed ovarian germ cell tumour composed of immature teratoma, yolk sac tumour and embryonal carcinoma. J Coll Physicians Surg Pak. 2014;24(Suppl 3):S198–200.PubMedGoogle Scholar
  17. Wei S, Baloch ZW, LiVolsi VA. Pathology of Struma Ovarii: a report of 96 cases. Endocr Pathol. 2015;26(4):342–8.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Pranab Dey
    • 1
  1. 1.Post Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

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