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3D Bioprinting of Adipose-Derived Stem Cells for Organ Manufacturing

  • Xiaohong WangEmail author
  • Chang Liu
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1078)

Abstract

Organ manufacturing is an attractive high-tech research field which can solve the serious donor shortage problems for allograft organ transplantation, high throughput drug screening, and energy metabolism model establishment. How to integrate heterogeneous cell types along with other biomaterials to form bioartificial organs is one of the kernel issues for organ manufacturing. At present, three-dimensional (3D) bioprinting of adipose-derives stem cell (ADSC) containing hydrogels has shown the most bright futures with respect to overcoming all the difficult problems encountered by tissue engineers over the last several decades. In this chapter, we briefly introduce the 3D ADSC bioprinting technologies for organ manufacturing, especially for the branched vascular network construction.

Keywords

Organ manufacturing Three-dimensional (3D) bioprintng Rapid prototyping Tissue engineering Biomaterials Stem cells 

Notes

Acknowledgments

The work was supported by grants from the National Natural Science Foundation of China (NSFC) (No. 81571832 & 81271665), the 2017 Discipline Promotion Project of China Medical University (CMU) (No. 3110117049), and the International Cooperation and Exchanges NSFC and Japanese Society for the Promotion of Science (JSPS) (No. 81411140040).

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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Center of Organ Manufacturing, Department of Tissue EngineeringChina Medical University (CMU)ShenyangPeople’s Republic of China
  2. 2.Center of Organ Manufacturing, Department of Mechanical EngineeringTsinghua UniversityBeijingPeople’s Republic of China
  3. 3.Tianjin Mifang Technology Company LimitedTianjinPeople’s Republic of China

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