Advertisement

Neuropharmacology of Lavender, Rosemary and Salvia

  • Amritpal Singh Saroya
  • Jaswinder Singh
Chapter

Abstract

English lavender and true lavender are common names of L. officinalis. The plant belongs to the family Lamiaceae and is native to the Mediterranean.

References

  1. Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther. 2003;28:53–9.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Akhondzadeh S, Kashani L, Fotouhi A, Jarvandi S, Mobaseri M, Moin M, Khani M, Abdelhalim A, Karim N, Chebib M, Aburjai T, Khan I, Johnston GA, Hanrahan J. Antidepressant, anxiolytic and Antinociceptive activities of constituents from Rosmarinus officinalis. J Pharm Pharm Sci. 2015;18:448–59.CrossRefGoogle Scholar
  3. Delaveau P, Guillemain J, Narcisse G, Rousseau A. Neuro-depressive properties of essential oil of lavender. C R Seances Soc Biol Fil. 1989;183:342–8.PubMedPubMedCentralGoogle Scholar
  4. Farimani MM, Miran M. Labdane diterpenoids from Salvia reuterana. Phytochemistry. 2014;108:264–9.CrossRefPubMedPubMedCentralGoogle Scholar
  5. Guillemain J, Rousseau A, Delaveau P. Neurodepressive effects of the essential oil of Lavandula angustifolia mill. Ann Pharm Fr. 1989;47:337–43.PubMedGoogle Scholar
  6. Heidari MR, Assadipour A, Rashid-farokhi P, Assad H, Mandegary A. Effect of Rosmarinus officinalis L. extract on the seizure induced by picrotoxin in mice. Pak J Biol Sci. 2005;8:1807–11.CrossRefGoogle Scholar
  7. Herrera-Ruiz M, García-Beltrán Y, Mora S, Díaz-Véliz G, Viana GS, Tortoriello J, Ramírez G. Antidepressant and anxiolytic effects of hydroalcoholic extract from Salvia elegans. J Ethnopharmacol. 2006;107:53–8.CrossRefPubMedGoogle Scholar
  8. Jamshidi AH, Baghalian K, Taghizadeh M. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuro-Psychopharmacol Biol Psychiatry. 2003;27:123–7.CrossRefGoogle Scholar
  9. Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Dienel A, Schläfke S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of ‘subsyndromal’ anxiety disorder: a randomized, double-blind, placebo controlled trial. Int Clin Psychopharmacol. 2010;25:277–87.CrossRefPubMedGoogle Scholar
  10. Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Schläfke S, Dienel A. Lavender oil preparation Silexan is effective in generalized anxiety disorder-a randomized, double-blind comparison to placebo and paroxetine. Int J Neuropsychopharmacol. 2014;17:859–69.CrossRefPubMedGoogle Scholar
  11. Kavvadias D, Monschein V, Sand P, Riederer P, Schreier P. Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor. Planta Med. 2003;69:113–7.CrossRefPubMedGoogle Scholar
  12. Kim SJ, Kim JS, Cho HS, Lee HJ, Kim SY, Kim S, Lee SY, Chun HS. Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells. Neuroreport. 2006;17:1729–33.CrossRefPubMedGoogle Scholar
  13. Lee IS, Lee GJ. Effects of lavender aromatherapy on insomnia and depression in women college students. Taehan Kanho Hakhoe Chi. 2006;36:136–43.PubMedGoogle Scholar
  14. Lewith GT, Godfrey AD, Prescott P. A single-blinded, randomized pilot study evaluating the aroma of Lavandula angustifolia as a treatment for mild insomnia. J Altern Complement Med. 2005;11:631–7.CrossRefPubMedGoogle Scholar
  15. Mirza M, Sefidkon F. Essential oil composition of two Salvia species from Iran, Salvia nemorosa L. and Salvia reuterana Boiss. Flav Frag J. 1999;14(4):230–2.CrossRefGoogle Scholar
  16. Naderi N, Akhavan N, Aziz Ahari F, Zamani N, Kamalinejad M, Shokrzadeh M, Ahangar N, Motamedi F. Effects of Hydroalcoholic extract from Salvia verticillata on pharmacological models of seizure, anxiety and depression in mice. Iran J Pharm Res. 2011;10:535–45.PubMedPubMedCentralGoogle Scholar
  17. Nikfarjam M, Parvin N, Assarzadegan N, Asghari S. The effects of Lavandula Angustifolia mill infusion on depression in patients using citalopram: a comparison study. Iran Red Crescent Med J. 2013;15:734–9.CrossRefPubMedPubMedCentralGoogle Scholar
  18. Perry NS, Houghton PJ, Theobald A, Jenner P, Perry EK. In-vitro inhibition of human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil and constituent terpenes. J Pharm Pharmacol. 2000;52:895–0.CrossRefPubMedGoogle Scholar
  19. Rabbani M, Sajjadi SE, Jafarian A, Vaseghi G. Anxiolytic effects of Salvia reuterana Boiss. On the elevated plus-maze model of anxiety in mice. J Ethnopharmacol. 2005;101:100–3.CrossRefPubMedGoogle Scholar
  20. Rahmati B, Kiasalari Z, Roghani M, Khalili M, Ansari F. Antidepressant and anxiolytic activity of Lavandula officinalis aerial parts hydroalcoholic extract in scopolamine-treated rats. Pharm Biol. 2017;55:958–65.CrossRefPubMedGoogle Scholar
  21. Seyedemadi P, Rahnema M, Bigdeli MR, Oryan S, Rafati H. The neuroprotective effect of rosemary (Rosmarinus officinalis L.) hydro-alcoholic extract on cerebral ischemic tolerance in experimental stroke. Iran J Pharm Res. 2016;15:875–83.PubMedPubMedCentralGoogle Scholar
  22. Tildesley NT, Kennedy DO, Perry EK, Ballard CG, Savelev S, Wesnes KA, Scholey AB. Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacol Biochem Behav. 2003;75:669–74.CrossRefPubMedGoogle Scholar
  23. Woelk H, Schläfke S. A multi-center, double-blind, randomised study of the lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010;17:94–9.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Amritpal Singh Saroya
    • 1
  • Jaswinder Singh
    • 2
  1. 1.Herbal ConsultantMohaliIndia
  2. 2.Department of PharmacologySri Guru Ram Das Institute of Medical ScienceAmritsarIndia

Personalised recommendations