Omics-Based Nanomedicine

  • Chirasmita Nayak
  • Ishwar Chandra
  • Poonam Singh
  • Sanjeev Kumar Singh


Traditionally “one-size-fits-all” paradigm for all patients within the disease has the limit of successful treatment. Personalized medicine aims to individualize therapeutic interventions, in combination of ex vivo omics data (i.e., genomics, proteomics, metabolomics, etc.) profiling and in vivo imaging insights on the type, the stage, and the grade of the disease called as theranostic. Personalized medicine has led to the discovery of various biomarkers that can detect the early stage of disease as well as response of bioactive molecules. Nanomedicine, the application of nanotechnology in medicine, holds great promise for diagnosing, treating, and preventing disease and traumatic injury and of relieving pain using molecular tools and molecular knowledge of the human body. Personalized nanomedicine has the power of integration of nanomedicine and molecular biomarkers to improve diagnosis, disease management, and prognosis as well as individualized drug selection by reducing side effects and cytotoxicity. In this book chapter, we have discussed about the leading technologies available for personalized nanomedicine and immense potential combination of nanomedicine with high-throughput omics technology.


Omics Nanomedicine NGS Personalized medicine Biomarkers 



SKS, CN, and IC thank the Department of Biotechnology (DBT), New Delhi for providing financial support.

Conflict of Interest

The author(s) declare that there is no conflict of interest.


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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Chirasmita Nayak
    • 1
  • Ishwar Chandra
    • 1
  • Poonam Singh
    • 2
  • Sanjeev Kumar Singh
    • 1
  1. 1.Computer Aided Drug Design and Molecular Modelling Lab, Department of BioinformaticsAlagappa UniversityKaraikudiIndia
  2. 2.Corrosion & Materials Protection DivisionC.S.I.R – Central Electrochemical Research Institute (CECRI)KaraikudiIndia

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