Fungal Nanotechnology: A New Approach Toward Efficient Biotechnology Application

  • Cintia Mariana Romero
  • Analía Alvarez
  • María Alejandra Martínez
  • Silvina Chaves


Nanotechnology is a wide developing area of the biotechnology since the important applications of nanoparticles (NPs) in different technologies. The NPs produced by green technologies have many advantages such as greater surface area and high catalytic activity, in addition to providing a suitable contact between the metal salt and enzyme. Fungi secrete proteins, enzymes, and reducing agents which can be used for the synthesis of metal NPs from metal salts.

The biosynthesis of metal NPs by fungi has been explored in recent years, evaluating the extracellular and intracellular chemistry of formation. Emphasis has been given to the potential of metal NPs as an antimicrobial agent to inhibit the growth of pathogenic bacteria and fungi and other potential applications such as their cytotoxic activity against cancer cell lines. Further, the metal NPs are being explored as promising candidates for several biomedical, pharmaceutical, and agricultural applications.


Nanoparticles Biosynthesis Antimicrobial Cytotoxicity Biomineralization 



This work was supported by the Agencia Nacional de Investigaciones Científicas y Técnicas (PICT 2974 and 0480), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET, PIP 0372), and Consejo Interuniversitario Nacional Consejo and Nacional de Investigaciones Científicas y Técnicas (CIN-CONICET, PDTS 474).


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Cintia Mariana Romero
    • 1
    • 2
  • Analía Alvarez
    • 1
    • 3
  • María Alejandra Martínez
    • 1
    • 4
  • Silvina Chaves
    • 5
  1. 1.Planta Piloto de Procesos Industriales Microbiológicos (PROIMI), CONICETSan Miguel de TucumánArgentina
  2. 2.Facultad de Bioquímica, Química y FarmaciaUniversidad Nacional de TucumánSan Miguel de TucumánArgentina
  3. 3.Facultad de Ciencias Naturales e IMLUniversidad Nacional de TucumánSan Miguel de TucumánArgentina
  4. 4.Facultad de Ciencias Exactas y TecnologíaUniversidad Nacional de TucumánSan Miguel de TucumánArgentina
  5. 5.Instituto de Medicina Molecular y Celular Aplicada. (IMMCA) CONICET-UNT-SIPROSAUniversidad Nacional de TucumánSan Miguel de TucumánArgentina

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