Botany, Chemistry, and Pharmaceutical Significance of Sida cordifolia: A Traditional Medicinal Plant

  • Hassan Ahmed
  • Abdul Shukor JuraimiEmail author
  • Mallappa Kumara Swamy
  • Muhammad Saiful Ahmad-Hamdani
  • Dzolkifli Omar
  • Mohd Yusop Rafii
  • Uma Rani SinniahEmail author
  • Mohd Sayeed Akhtar


Sida cordifolia Linn. belonging to the family, Malvaceae has been widely employed in traditional medications in many parts of the world including India, Brazil, and other Asian and African countries. The plant is extensively used in the Ayurvedic medicine preparation. There are more than 200 plant species within the genus Sida, which are distributed predominantly in the tropical regions. The correct taxonomic identification is a major concern due to the fact that S. cordifolia looks morphologically similar with its related species. It possesses activity against various human ailments, including cancer, asthma, cough, diarrhea, malaria, gonorrhea, tuberculosis, obesity, ulcer, Parkinson’s disease, urinary infections, and many others. The medical importance of this plant is mainly correlated to the occurrence of diverse biologically active phytochemical compounds such as alkaloids, flavonoids, and steroids. The major compounds include β-phenylamines, 2-carboxylated tryptamines, quinazoline, quinoline, indole, ephedrine, vasicinone, 5-3-isoprenyl flavone, 5,7-dihydroxy-3-isoprenyl flavone, and 6-(isoprenyl)- 3-methoxy- 8-C-β-D-glucosyl-kaempferol 3-O-β-D-glucosyl[1–4]-α-D-glucoside. The literature survey reveals that most of the pharmacological investigations on S. cordifolia are limited to crude plant extracts and few isolated pure compounds. Therefore, there is a need to evaluate many other unexplored bioactive phytoconstituents with evidences so as to justify the traditional usages of S. cordifolia. Furthermore, detailed studies on the action of mechanisms of these isolated compounds supported by clinical research are necessary for validating their application in contemporary medicines. The aim of the present chapter is to provide a detailed information on the ethnobotanical, phytochemical, and pharmacological aspects of S. cordifolia.


Biological activities Herb Medicinal plant Pharmacology Phytochemicals Sida cordifolia Therapy Traditional medicine 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Hassan Ahmed
    • 1
    • 2
  • Abdul Shukor Juraimi
    • 2
    Email author
  • Mallappa Kumara Swamy
    • 2
  • Muhammad Saiful Ahmad-Hamdani
    • 2
  • Dzolkifli Omar
    • 3
  • Mohd Yusop Rafii
    • 4
  • Uma Rani Sinniah
    • 2
    Email author
  • Mohd Sayeed Akhtar
    • 5
  1. 1.Department of Biological sciencesUsmanu Danfodiyo University SokotoSokotoNigeria
  2. 2.Department of Crop Science, Faculty of AgricultureUniversiti Putra MalaysiaSerdangMalaysia
  3. 3.Department of Plant Protection, Faculty of AgricultureUniversiti Putra MalaysiaSerdangMalaysia
  4. 4.Institute of Tropical AgricultureUniversiti Putra MalaysiaSerdangMalaysia
  5. 5.Department of BotanyGandhi Faiz-e-Aam CollegeShahjahanpurIndia

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