Advertisement

Anticancer Plants and Their Conservation Strategies: An Update

  • Vankayalapati Vijaya KumarEmail author
  • Mallappa Kumara Swamy
  • Mohd. Sayeed Akhtar
Chapter

Abstract

Cancer is a multi-disease involving an abnormal growth of cells with the possibility of spreading or invading into other tissues of the body. Cancer harms the body by uncontrolled division of cells forming lumps or mass of tissue called tumor, which can be either benign or malignant type. The current practice of cancer treatments such as chemotherapy and radiotherapy is painful and is associated with side effects. Various chemical compounds including alkaloids, flavonoids, saponins, and terpenes found in plants, such as Colchicum autumnale, Taxus baccata, T. brevifolia, Catharanthus roseus, Curcuma longa, Glycyrrhiza glabra, etc. are recorded with anticancer potential, and some of which are already being used as anticancer agents. These natural compounds can enhance the body’s immunity and help in inhibiting the proliferation of cancer cells or cancer prognosis. Therefore in recent times, plant-based anticancer drugs are highly appreciated to the fact that they are safe when compared to the synthetic ones. In this regard, medicinal plants have been widely exploited in nature leading to habitat loss, and some species are in the margin of extinction. Further, loss of habitats due to environmental disturbance, industrialization, and urbanization has indirectly contributed to the endangered status for many plants around the globe. Hence, conservation of these threatened medicinal plants is a great challenge to the herbal, nutraceutical, and pharmaceutical industries. There is a need to adopt both in situ and ex situ conservation strategies, and though the micropropagation technique of biotechnological tools is much admired. Moreover, cryopreservation approach can be used for a long-term conservation. Therefore, this chapter provides an overview of anticancer plants and various conservational strategies used for some of the important anticancer plants.

Keywords

Alkaloids Anticancer compounds Conservation Cryopreservation Tumors 

Notes

Acknowledgments

The author is thankful to the Management of Core Green Sugar and Fuels Pvt. Ltd. for giving an opportunity and encouragement in preparation of this chapter.

References

  1. Abbasin Z, Zamani S, Movahedi S, Khaksar G, Tabatabaei BES (2010) In vitro micropropagation of Yew (Taxus baccata) and production of plantlets. Biotechnology 9:48–54CrossRefGoogle Scholar
  2. Abdi G, Hedayat M, Modarresi M (2013) In vitro micropropagation of Aloe vera-impacts of plant growth regulators, media and type of explants. J Biol Environ Sci 7:19–24Google Scholar
  3. Aguoru CU, Azua ET, Olasan OJ (2015) Approaches to minimizing and overcoming current biodiversity loss. Brit J Env Sci 3:12–26Google Scholar
  4. Akshay KR, Sudharani N, Anjali KB, Deepak TM (2014) Biodiversity and strategies for conservation of rare, endangered and threatened medicinal plants. Res Rev: J Pharmacogn Phytochem 2:12–20Google Scholar
  5. Al-Mamun MA, Akhter R, Rahman A, Ferdousi Z (2015) Efficient in vitro micro propagation of Andrographis paniculata and evaluation of antibacterial activity from its crude protein extract. Eur J Med Plants 6:231–241CrossRefGoogle Scholar
  6. Amin A, Gali-Muhtasib H, Ocker M, Schneider-Stock R (2009) Overview of major classes of plant-derived anticancer drugs. Int J Biomed Sci 5:1–11PubMedPubMedCentralGoogle Scholar
  7. Amirthalingam M (2016) Sacred groves of India-an overview. Int J Curr Res Biosci Plant Biol 3:64–74CrossRefGoogle Scholar
  8. Arumugam G, Swamy MK, Sinniah UR (2016) Plectranthus amboinicus (Lour.) Spreng: botanical, phytochemical, pharmacological and nutritional significance. Molecules 21:369PubMedPubMedCentralCrossRefGoogle Scholar
  9. Aslam J, Mujib A, Fatima Z, Sharma MP (2010) Variations in vinblastine production at different stages of somatic embryogenesis, embryo, and field grown plantlets of Catharanthus roseus L. (G) Don, as revealed by HPLC. In Vitro Cell Dev Biol 46:348–353CrossRefGoogle Scholar
  10. Aslam MS, Naveed S, Ahmed A, Abbas Z, Gull I, Athar MA (2014) Side effects of chemotherapy in cancer patients and evaluation of patients opinion about starvation based differential chemotherapy. J Cancer Ther 5:817–822CrossRefGoogle Scholar
  11. Autade RH, Fargade SA, Savant AR, Gangurde SS, Choudhary RS, Dighe SS (2016) Micropropagation of Ashwagandha (Withania somnifera). Biosci Biotech Res Comm 9:88–93Google Scholar
  12. Baharak BS, Mansoor O, Reza NM, Farhad HA, Sepideh KJ, Mehdi S, Mohammad S (2014) Effect of explants, salts concentration medium and hormone treatments on Taxus baccata in vitro culture. Int J Biosci 5:1–9Google Scholar
  13. Banerjee A, Bandyopadhyay S, Raychaudhuri SS (2012) In vitro regeneration of Hypericum perforatum L. using thidiazuron and analysis of genetic stability of regenerants. Indian J Biotechnol 11:92–98Google Scholar
  14. Bartosch B (2010) Hepatitis B and C viruses and hepatocellular carcinoma. Viruses 2:1504–1509CrossRefPubMedPubMedCentralGoogle Scholar
  15. Bassil KL, Vakil C, Sanborn M, Cole DC, Kaur JS, Kerr KJ (2007) Cancer health effects of pesticides. Can Fam Physician 53:1704–1711PubMedPubMedCentralGoogle Scholar
  16. Beyersmann D, Hartwig A (2008) Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. Arch Toxicol 82:493–512CrossRefPubMedGoogle Scholar
  17. Bhalerao BM, Vishwakarma KS, Maheshwari VL (2013) Tinospora cordifolia (Willd.) Miers ex Hook f. & Thoms. plant tissue culture and comparative chemo-profiling study as a function of different supporting trees. Indian J Nat Prod Resour 4:380–386Google Scholar
  18. Bindhu KB (2013) In vitro propagation of Aeglemarmelos through nodal explants. Int J Sci Res 4:691–694Google Scholar
  19. Biswas BC (2010) Cultivation of medicinal plant success stories of two farmers. Fertil Market News 41:1–4Google Scholar
  20. Braaten KP, Laufer MR (2008) Human papillomavirus (HPV), HPV-related disease, and the HPV vaccine. Rev Obstet Gynecol 1:2–10PubMedPubMedCentralGoogle Scholar
  21. Brearley TA, Vaidya BN, Joshee N (2014) Cytokinin, carbon source, and acclimatization requirements for in vitro propagation of Scutellaria barbata Don. and Scutellaria racemosa Pers. Am J Plant Sci 5:3662–3672Google Scholar
  22. Bustam S, Swamy MK, Sinniah UR (2017) Simple and efficient in vitro method of storing Dendrobium sw. shavin white protocorm like bodies (PLBs). Bangladesh J Bot 46:439–449Google Scholar
  23. Chaudhry H, Fatima N, Ahmad IZ (2014) Establishment of callus and cell suspension cultures of Nigella sativa L. for thymol production. Int J Pharm Pharm Sci 6:788–794Google Scholar
  24. Clapp RW, Jacobs MM, Loechler EL (2008) Environmental and occupational causes of cancer: new evidence 2005–2007. Rev Environ Health 23:1–37CrossRefPubMedPubMedCentralGoogle Scholar
  25. Coetzer KL, Witkowski ET, Erasmus BF (2014) Reviewing biosphere reserves globally: effective conservation action or bureaucratic label. Biol Rev 89:82–104CrossRefPubMedGoogle Scholar
  26. Correa P, Piazuelo MB (2011) Helicobacter pylori infection and gastric adenocarcinoma. US Gastroenterol Hepatol Rev 7:59–64PubMedPubMedCentralGoogle Scholar
  27. Cruz-Cruz CA, González-Arnao MT, Engelmann F (2013) Biotechnology and conservation of plant biodiversity. Resources 2:73–95CrossRefGoogle Scholar
  28. D’Orazio J, Jarrett S, Amaro-Ortiz A, Scott T (2013) UV radiation and the skin. Int J Mol Sci 14:12222–12248CrossRefPubMedPubMedCentralGoogle Scholar
  29. Daradkeh NQ, Shibli RA, Makhadmeh IM, Alali F, Al-Qudah TS (2012a) Cell suspension and in vitro production of colchicine in wild Colchicum hierosolymitanum Feib. Open Conf Proc J 3:52–59CrossRefGoogle Scholar
  30. Daradkeh NQ, Shibli RA, Makhadmeh IM, Alali F, Al-Qudah TS (2012b) Callus culture and somatic embryogenesis in wild Colchicum hierosolymitanum Feib. Jordan J Agric Sci 8:536–556Google Scholar
  31. David D, Yan Ji T, Gansau JA (2016) In vitro propagation of Zingiber officinale Rosc. ‘Tambunan’. Trans Sci Technol 3:162–167Google Scholar
  32. Dixit S, Ahuja S, Narula A, Srivastava PS (2005) Cryopreservation: a potential tool for long-term conservation of medicinal plants. In: Srivastava PS, Narula A, Srivastava S (eds) Plant biotechnology and molecular markers. Springer, Dordrecht, pp 278–288Google Scholar
  33. Engelmann F (2004) Plant cryopreservation: progress and prospects. In Vitro Cell Dev Biol Plant 40:427–433CrossRefGoogle Scholar
  34. Engelmann F (2011) Use of biotechnologies for the conservation of plant biodiversity. In Vitro Cell Dev Biol Plant 47:5–16CrossRefGoogle Scholar
  35. ENVIS (2017) National parks-ENVIS centre on wildlife and protected areas (http://wiienvis.nic.in/Database/npa_8231.aspx; Assessed on 10th July 2017)
  36. Farag S, Kayser O (2015) Cannabinoids production by hairy root cultures of Cannabis sativa L. Am J Plant Sci 6:1874–1884CrossRefGoogle Scholar
  37. Fatima S, Mujib A, Nasim SA, Siddiqui ZH (2009) Cryopreservation of embryogenic cell suspensions of Catharanthus roseus L. (G) Don. Plant Cell Tissue Organ Cult 98:1–9CrossRefGoogle Scholar
  38. Fulzele DP, Satdive R, Kamble S, Singh S, Singh S (2015) Improvement of anticancer drug camptothecin production by gamma irradiation on callus cultures of Nothapodytes foetida. Int J Pharm Res Allied Sci 4:19–27Google Scholar
  39. Gandhi MK (2006) Epstein–Barr virus-associated lymphomas. Expert Rev Anti-Infect Ther 4:77–89CrossRefPubMedGoogle Scholar
  40. Ganesan A, Marichamy K, Thagamariappan J (2016) Development of medicinal plants sector in India-an empirical study. Int J Eng Technol Manag Appl Sci 4:82–88Google Scholar
  41. Gehlot A, Arya ID, Arya S, Gupta RK, Tripathi A, Sharma SK (2014) Role of tryptophan on in vitro rooting in microshoots of Azadirachta indica A. Juss (Neem). Adv For Sci Cuiabá 1:101–106Google Scholar
  42. Ghosh A, Chatterjee P, Ghosh P (2013) A protocol for rapid propagation of genetically true to type Indian turmeric (Curcuma longa L.) through in vitro culture technique. Adv Appl Sci Res 4:39–45Google Scholar
  43. Grywalska E, Rolinski J (2015) Epstein-barr virus–associated lymphomas. Semin Oncol 42:291–303CrossRefPubMedGoogle Scholar
  44. GSPC (2010) Global strategy for plant conservation (http://www.plants2010.org; Accessed on 10th July 2017)
  45. Guo Q, Zhou J, Wang Z, Yang H (2012) In vitro rooting of Podophyllum hexandrum and transplanting technique. Engineering 5:142–145CrossRefGoogle Scholar
  46. Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57–70CrossRefPubMedPubMedCentralGoogle Scholar
  47. Houllou LM, de Souza RA, Pacheco dos Santos EC, Pereira da Silva JJ, Barbosa MR, Guimaraes Sauve JP, Harand EW (2015) Clonal propagation of neem (Azadirachta indica A. Juss.) via direct and indirect in vitro regeneration. Rev Arvore 39:439–445CrossRefGoogle Scholar
  48. Inwanna OU, Samala S, Chanpradit C, Beem NCV (2014) Effects of culture media and explant types on callus and shoot induction of Annona muricata L. Malaya J Biosci 1:155–159Google Scholar
  49. Ioja-Boldura O-M, Radu F, Popescu S, Borozan A (2010) Regeneration, micropropagation, callus cultures and somatic embryogenesis of common sage (Salvia officinalis L.) Bull UASVM Horticul 67:308–313Google Scholar
  50. Iskandar NN, Iriawati (2016) Vinblastine and vincristine production on Madagascar periwinkle (Catharanthus roseus (L.) G. Don.) callus culture treated with polyethylene glycol. Makara J Sci 20:7–16CrossRefGoogle Scholar
  51. IUCN (2017) IUCN Red list of endangered species (http://www.iucnredlist.org; Assessed on 10th July 2017)
  52. Jan T, Khatoon K (2014) In vitro regeneration of Salvia santolinifolia. Pak J Bot 46:325–328Google Scholar
  53. Jan T, Naqvi B, Qadri R (2015) In vitro mass multiplication and isolation of natural products from callus tissues of Salvia santolinifolia (Boiss). Biol Chem Res:320–328Google Scholar
  54. Kajani AA, Moghim S, Mofid MR (2012) Optimization of the basal medium for improving production and secretion of taxanes from suspension cell culture of Taxus baccata L. DARU J Pharm Sci 20:54CrossRefGoogle Scholar
  55. Kang SM, Min JY, Park DJ, Jeong MJ, Song HJ, Heo CM, Moon HS, Kim JG, Karigar CS, Choi MS (2011) Effects of plant growth regulators on rapid in vitro propagation of Camptotheca acuminata from axillary buds. J Agric Life Sci 45:33–40Google Scholar
  56. Kasagana VN, Karumuri SS (2011) Conservation of medicinal plants (past, present & future trends). J Pharm Sci Res 3:1378–1386Google Scholar
  57. Kaushik PS, Swamy MK, Balasubramanya S, Anuradha M (2015) Rapid plant regeneration, analysis of genetic fidelity and camptothecin content of micropropagated plants of Ophiorrhiza mungos Linn.-a potent anticancer plant. J Crop Sci Biotechnol 18:1–8CrossRefGoogle Scholar
  58. Kaveri S, Rao S (2015) In vitro seed germination and embryo culture in Nothapodytes foetida (Wight) Sleumer. Int Lett Nat Sci 48:23–31Google Scholar
  59. Kaviani B (2011) Conservation of plant genetic resources by cryopreservation. Aust J Crop Sci 5:778–800Google Scholar
  60. Kavitha MS, Wesely EG, Mehalingam P (2012) Direct multiple shoot regeneration from shoot tip and nodal explants of Solanum nigrum L., a medicinal herb. J Ornam Horti Plants 2:65–72Google Scholar
  61. Khadke S, Kuvalekar A (2013) Direct somatic embryogenesis and plant regeneration from leaf and stem explants of Nothapodytes foetida: a critically endangered plant species. Int J Plant Ani Environ Sci 3:257–264Google Scholar
  62. Khan H (2014) Medicinal plants need biological screening: a future treasure as therapeutic agents. Biol Med 6:1–2CrossRefGoogle Scholar
  63. Khandekar V, Srivastava A (2014) Ecosystem biodiversity of India. In: Biodiversity-the dynamic balance of the planet 2014. InTech ( https://doi.org/10.5772/58431; Assessed on 10th July 2017)Google Scholar
  64. Kulkarni A (2012) Biodiversity and sustainable development: a critical analysis. Int J Sci Eng Res 3:1–9Google Scholar
  65. Kumaraswamy M, Anuradha M (2010) Micropropagation of Pogostemon cablin Benth. through direct regeneration for production of true to type plants. Plant Tiss Cult Biotechnol 20:81–89Google Scholar
  66. Lata H, Chandra S, Techen N, Khan IA, El Sohly MA (2016) In vitro mass propagation of Cannabis sativa L.: a protocol refinement using novel aromatic cytokinin meta-topolin and the assessment of eco-physiological, biochemical and genetic fidelity of micropropagated plants. J Appl Res Med Arom Plants 3:18–26CrossRefGoogle Scholar
  67. Ledda C, Loreto C, Zammit C, Marconi A, Fago L, Matera S, Costanzo V, Fuccio Sanzà G, Palmucci S, Ferrante M, Costa C (2017) Non-infective occupational risk factors for hepatocellular carcinoma: a review. Mol Med Rep 15:511–533CrossRefPubMedGoogle Scholar
  68. Mahdinejad N, Fakheri BA, Ghanbari S (2015) Effects of growth regulators on in vitro callogenesis of Taxus baccata L. Biol Forum 7:142–145Google Scholar
  69. Mehta MJ, Sharma A, Sharma N, Megwal S, Sharma G, Gehlot P, Naruka R (2013) An improved method for callus culture and in vitro propagation of garlic (Allium sativum L.) Int J Pure App Biosci 1:1–6Google Scholar
  70. Michael L (2003) Beating cancer with natural medicine (https://www.drlam.com/book/CancerBook.pdf; Assessed on 10th July 2017)
  71. MOEF (2015) Annual report 2014–15, Ministry of Environment, Forests and Climate change (http://www.moef.gov.in/sites/default/files/Environment%20Annual%20Report%20%20Eng.pdf; Assessed on 10th July 2017)
  72. Mohanty SK, Swamy MK, Sinniah UR, Anuradha M (2017) Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): botanical, agronomical, phytochemical, pharmacological, and biotechnological aspects. Molecules 22:1019CrossRefGoogle Scholar
  73. Movahedi M, Ghasemi-Omran VO, Torabi S (2015) The effect of different concentrations of TDZ and BA on in vitro regeneration of Iranian cannabis (Cannabis sativa) using cotyledon and epicotyl explants. J Plant Mol Breed 3:20–27Google Scholar
  74. Muhumuza M, Balkwill K (2013) Factors affecting the success of conserving biodiversity in national parks: a review of case studies from Africa. Int J Biodiver 2013:798101.  https://doi.org/10.1155/2013/798101 CrossRefGoogle Scholar
  75. Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 15:473–497CrossRefGoogle Scholar
  76. Nair DS, Reghunath BR, Soni KB, Alex S (2016) In vitro regeneration and conservation of Indigo (Indigofera tinctoria L.) by slow growth induction. Int J Environ Agric Biotechnol 1:873–884Google Scholar
  77. Namdeo AG, Priya T, Bhosale BB (2012) Micropropagation and production of camptothecin from in vitro plants of Ophiorrhiza mungos. Asian Pac J Trop Biomed 2012:S662–S666CrossRefGoogle Scholar
  78. Narayanan DL, Saladi RN, Fox JL (2010) Ultraviolet radiation and skin cancer. Int J Dermatol 49:978–986CrossRefPubMedGoogle Scholar
  79. Nasim SA, Dhir B, Kapoor R, Fatima S, Mahmooduzzafar MA (2010) Alliin production in various tissues and organs of Allium sativum grown under normal and sulphur-supplemented in vitro conditions. Plant Cell Tissue Organ Cult 101:59–63CrossRefGoogle Scholar
  80. Ni X, Wen S, Wang W, Wang X, Xu H, Kai G (2011) Enhancement of camptothecin production in Campotheca acuminata hairy roots by over expressing ORCA3 gene. J App Pharm Sci 1:85–88Google Scholar
  81. NIH (2003) Cancer and environment. What you need to know and what you can do. NIH publication no. 03-2039, p 42 (https://www.niehs.nih.gov/health/materials/cancer_ and_the_environment_508.pdf; Assessed on 10th July 2017)
  82. Noor EEM, Sinniah UR, Swamy MK (2017) Micropropagation of Musa acuminata Var. Zebrina (Van Houtte ex Planch.) nasution, an ornamental plant for the horticulture industry. Bangladesh J Bot 46:297–304Google Scholar
  83. Padmapriya H, Karthikeyan AVP, Jahir Hussain G, Karthi C, Velayutham P (2011) An efficient protocol for in vitro propagation of Solanum nigrum L. from nodal explants. J Agric Technol 7:1063–1073Google Scholar
  84. Pandey M, Debnath M, Gupta S, Chikara SK (2011) Phytomedicine: an ancient approach turning into future potential source of therapeutics. J Pharmacogn Phytother 3:113–117Google Scholar
  85. Pandey S, Bahadur AN, Kanungo VK, Tiwari U (2014) In-vitro propagation of a medicinal plant Catharanthus roseus L. (G.) Don. Indian J Life Sci 4:125–128Google Scholar
  86. Pandurangan B, Philomina D (2010) Effect of nutritional factors and precursors on formation of colchicine in Gloriosa superba in vitro. Res Biotechnol 1:29–37Google Scholar
  87. Pathak K, Das RJ (2013) Herbal medicine- a rational approach in health care system. Int J Herb Med 1:86–89Google Scholar
  88. Perez J, Guillen A, Ramos K, Engelmann F, Abdelnour-Esquivel A (2015) Cryopreservation of cat’s claw (Uncaria tomentosa). Am J Plant Sci 6:2960–2972CrossRefGoogle Scholar
  89. Petijová L, Skyba M, Cellárová E (2012) Genotype-dependent response of St. John’s wort (Hypericum perforatum L.) shoot tips to cryogenic treatment: effect of pre-culture conditions on post-thaw recovery. Plant Omics J 5:291–297Google Scholar
  90. Prakash O, Kumar A, Kumar P, Ajeet A (2013) Anticancer potential of plants and natural products: a review. Am J Pharmacol Sci 1:104–115Google Scholar
  91. Prakash L, Middha SK, Mohanty SK, Swamy MK (2016) Micropropagation and validation of genetic and biochemical fidelity among regenerants of Nothapodytes nimmoniana (Graham) Mabb. employing ISSR markers and HPLC. 3. Biotech 6:171Google Scholar
  92. Puhan P, Rath SP (2012) In vitro propagation of Aegle marmelos (L.) corr., a medicinal plant through axillary bud multiplication. Adv Biosci Biotechnol 3:121–125Google Scholar
  93. Radha RK, Decruse SW, Krishnan PN (2010) Cryopreservation of excised embryonic axes of Nothapodytes nimmoniana (Graham) Mobberley-a vulnerable medicinal tree species of the western ghats. Indian J Biotechnol 9:435–437Google Scholar
  94. Rai MK (2010) Biotechnological strategies for conservation of rare and endangered medicinal plants. Biodiversitas 11:157–166CrossRefGoogle Scholar
  95. Rajesh M, Sivanandhan G, Subramanyam K, Kapildev G, Jaganath B, Kasthurirengan S, Manickavasagam M, Ganapathi A (2014) Establishment of somatic embryogenesis and podophyllotoxin production in liquid shake cultures of Podophyllum hexandrum Royle. Indust Crops Prod 60:66–74CrossRefGoogle Scholar
  96. Rajora RK, Sharma NK, Sharma V (2013) Effect of plant growth regulators on micro-propagation of Catharanthus roseus. Int J Adv Biotechnol Res 4:123–130Google Scholar
  97. Rands MRW, Adams WM, Bennun L, Butchart SHM, Clements A, Coomes D, Entwistle A, Hodge I, Kapos V, Scharlemann JPW, Sutherland WJ, Bhaskar V (2010) Biodiversity conservation: challenges beyond 2010. Science 329:1298–1303CrossRefPubMedGoogle Scholar
  98. Rani A, Kumar M, Kumar S (2014) In vitro propagation of Withania somnifera (L.) Dunal. from shoot apex explants. J Appl Nat Sci 6:159–163CrossRefGoogle Scholar
  99. Rao S, Teesta VK, Bhattrai A, Khushi K, Bhat S (2012) In vitro propagation of Withania somnifera and estimation of with anolides for neurological disorders. J Pharmacogn 3:85–87Google Scholar
  100. Rasool Hassan BA (2012) Medicinal plants (importance and uses). Pharma Anal Acta 3:e139.  https://doi.org/10.4172/2153-2435.1000e139
  101. Rathore V, Gupta D (2013) In vitro clonal propagation of Solanum nigrum. Res J Chem Environ Sci 1:32–33Google Scholar
  102. Reed MG, Egunyu F (2013) Management effectiveness in UNESCO biosphere reserves: learning from Canadian periodic reviews. Environ Sci Pol 25:107–117CrossRefGoogle Scholar
  103. Reed BM, Sarasan V, Kane M, Bunn E, Pence VC (2011) Biodiversity conservation and conservation biotechnology tools. In Vitro Cell Dev Biol 47:1–4CrossRefGoogle Scholar
  104. Rezaei A, Ghanati F, Dehaghi MA (2011) Stimulation of taxol production by combined salicylic acid elicitation and sonication in Taxus baccata cell culture. Int Conf Life Sci Technol 3:193–197Google Scholar
  105. Rousselot P, Labaume S, Marolleau JP, Larghero J, Noguera MH, Brouet JC, Fermand JP (1999) Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients. Cancer Res 59:1041–1048PubMedGoogle Scholar
  106. Safarpour S, Sinniah UR, Subramaniam S, Swamy MK (2017) A novel technique for Musa acuminata Colla ‘Grand Naine’ (AAA) micropropagation through transverse sectioning of the shoot apex. In vitro Cell Dev Biol 2017:1–13 doi: https://doi.org/10.1007/s11627-017-9809-6 CrossRefGoogle Scholar
  107. Saha SP, Bhalla DK, Whayne TF, Gairola CG (2007) Cigarette smoke and adverse health effects: an overview of research trends and future needs. Int J Angiol 16:77–83CrossRefPubMedPubMedCentralGoogle Scholar
  108. Sawaengsak W, Saisavoey T, Chuntaratin P, Karnchanatat A (2011) Micropropagation of the medicinal herb Glycyrrhiza glabra L., through shoot tip explant culture and glycyrrhizin detection. Int Res J Plant Sci 2:129–136Google Scholar
  109. Sbeity H, Younes R (2015) Review of optimization methods for cancer chemotherapy treatment planning. J Comp Sci Syst Biol 8:74–95Google Scholar
  110. Schinzari V, Barnaba V, Piconese S (2015) Chronic hepatitis B virus and hepatitis C virus infections and cancer: synergy between viral and host factors. Clin Microbiol Infect 21:969–974CrossRefPubMedGoogle Scholar
  111. Selvarasu A, Kandhasamy R (2012) In vitrotuberization of glory lily (Gloriosa superba L.) J Hortic For 4:81–84Google Scholar
  112. Sen-Rong H, Ming-Hua YA (2012) Simple and efficient protocol for cryopreservation of embryogenic calli of the medicinal plant Anemarrhena asphodeloides Bunge by vitrification. Plant Cell Tissue Organ Cult 109:287–296CrossRefGoogle Scholar
  113. Seyfried TN, Flores RE, Poff AM, D’Agostino DP (2014) Cancer as a metabolic disease. Implication for novel therapeutics Carcinogenesis 35:515–527CrossRefGoogle Scholar
  114. Sharma S, Thokchom R (2014) A review on endangered medicinal plants of India and their conservation. J Crop and Weed 10:205–218Google Scholar
  115. Shivanna MB, Nagashree BR, Gurumurthy BR (2013) In vitro response of Azadirachta indicat o salinity stress and its effect of certain osmoprotectants and antioxidative enzymes. Int J Pharm Bio Sci 4:591–602Google Scholar
  116. Sivakumar V, Rajan MSD, Sadiq AM, Jayanthi M (2014) In vitro micropropagation of Tinospora cordifolia (Willd.) Miers ex. Hook. F. & Thoms-an important medicinal plant. J Pharmacogn Phytochem 3:5–10Google Scholar
  117. Siwach M, Siwach P, Solanki P, Gill AR (2013) Biodiversity conservation of Himalayan medicinal plants in India: a retrospective analysis for a better vision. Int J Biodiver Conserv 5:529–540Google Scholar
  118. Sudipta KM, Kumara Swamy M, Balasubramanya S, Anuradha M (2011) Cost effective approach for in vitro propagation of (Leptadenia reticulata Wight & Arn.)- a threatened plant of medicinal importance. J Phytology 3:72–79Google Scholar
  119. Swamy MK, Sinniah UR (2015) A comprehensive review on the phytochemical constituents and pharmacological activities of Pogostemon cablin Benth.: an aromatic medicinal plant of industrial importance. Molecules 20:8521–8547CrossRefPubMedGoogle Scholar
  120. Swamy MK, Sinniah UR (2016) Patchouli (Pogostemon cablin Benth.): botany, agrotechnology and biotechnological aspects. Indust Crop Prod 87:161–176CrossRefGoogle Scholar
  121. Swamy MK, Balasubramanya S, Anuradha M (2009) Germplasm conservation of patchouli (Pogostemon cablin Benth.) by encapsulation of in vitro derived nodal segments. Int J Biodvers Conserv 1:224–230Google Scholar
  122. Swamy MK, Balasubramanya S, Anuradha M (2010) In vitro multiplication of Pogostemon cablin Benth. through direct regeneration. Afr J Biotechnol 9:2069–2075Google Scholar
  123. Swamy MK, Mohanty SK, Anuradha M (2014) The effect of plant growth regulators and natural supplements on in vitro propagation of Pogostemon cablin Benth. J Crop Sci Biotech 17:71–78CrossRefGoogle Scholar
  124. Swamy MK, Sinniah UR, Akhtar MS (2015a) In vitro pharmacological activities and GC-MS analysis of different solvent extracts of Lantana camara leaves collected from tropical region of Malaysia. Evidence-Based Compl Altern Med 2015:506413.  https://doi.org/10.1155/2015/506413
  125. Swamy MK, Mohanty SK, Sinniah UR, Maniyam A (2015b) Evaluation of patchouli (Pogostemon cablin Benth.) cultivars for growth, yield and quality parameters. J Essent Oil Bear Plants 18:826–832CrossRefGoogle Scholar
  126. Swamy MK, Arumugam G, Kaur R, Ghasemzadeh A, Yusoff MM, Sinniah UR (2017) GC-MS based metabolite profiling, antioxidant and antimicrobial properties of different solvent extracts of Malaysian Plectranthus amboinicus leaves. Evidence-Based Compl Altern Med 2017:1517683.  https://doi.org/10.1155/2017/1517683 CrossRefGoogle Scholar
  127. Tasheva K, Kosturkova G (2012) The role of biotechnology for conservation and biologically active substances production of Rhodiola rosea: endangered medicinal species. The Sci World J 2012:274942.  https://doi.org/10.1100/2012/274942 CrossRefGoogle Scholar
  128. Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ (2012) Heavy metal toxicity and the environment. EXS 101:133–164.  https://doi.org/10.1007/978-3-7643-8340-4_6
  129. Tejavathi DH, Raveesha HR, Sobha K (2012) Organogenesis from the cultures of Nothapodytes foetida (Wight) Sleumer raised on TDZ supplemented media. Indian J Biotechnol 11:205–209Google Scholar
  130. Umadevi M, Kumar KPS, Bhowmik D, Duraivel S (2013) Traditionally used anticancer herbs in India. J Med Plants Stud 1:56–74Google Scholar
  131. UNDP (2010a) Development Goal 7 (http://www.un.org/en/mdg/summit2010/; Assessed on 10th July 2017)
  132. UNDP (2010b) Millennium Development Goals (http://www.undp.org/mdg/; Assessed on 10th July 2017)
  133. UNEP (1992) Convention on biological diversity, (NA92-7807), New York, USAGoogle Scholar
  134. Upadhyay RK, Baksh H, Patra DD, Tewari SK, Sharma SK, Katiyar RS (2011) Integrated weed management of medicinal plants in India. Int J Med Arom Plants 1:51–56Google Scholar
  135. Urruticoechea A, Alemany R, Balart J, Villanueva A, Viñals F, Capellá G (2010) Recent advances in cancer therapy: an overview. Curr Pharm Des 16:3–10CrossRefPubMedGoogle Scholar
  136. Vijay R, Shukla J, Saxena R (2016) Micropropagation of Plumbago zeylanica L.: an important medicinal plant of India. Int J Pure App Biosci 4:159–167CrossRefGoogle Scholar
  137. Wroblewski LE, Peek RM, Wilson KT (2010) Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev 23:713–739CrossRefPubMedPubMedCentralGoogle Scholar
  138. Yedjou CG, Tchounwou PB (2007) In-vitro cytotoxic and genotoxic effects of arsenic trioxide on human leukemia (HL-60) cells using the MTT and alkaline single cell gel electrophoresis (Comet) assays. Mol Cell Biochem 301:123–130CrossRefPubMedPubMedCentralGoogle Scholar
  139. Zuraida AR, Mohd Shukri MA, Erny Sabrina MN, Ayu Nazreena O, Che Radziah CZ, Pavallekoodi G, Sreeramanan S (2016) Micropropagation of ginger (Zingiber officinale var. rubrum) using buds from microshoots. Pak J Bot 48:1153–1158Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Vankayalapati Vijaya Kumar
    • 1
    Email author
  • Mallappa Kumara Swamy
    • 2
  • Mohd. Sayeed Akhtar
    • 3
  1. 1.Core Green Sugar and Fuels Private LimitedTumkur Village, Shahapur Taluk, Yadgir DistrictIndia
  2. 2.Department of Crop Science, Faculty of AgricultureUniversiti Putra MalaysiaSerdangMalaysia
  3. 3.Department of BotanyGandhi Faiz-e-Aam CollegeShahjahanpurIndia

Personalised recommendations