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Expedient Synthesis of Diverse Spirooxindoles via Multicomponent Approach in Presence of Green Catalyst

  • Ankita Chaudhary
  • Pooja Saluja
  • Garima Khanna
Conference paper

Abstract

An efficient, convenient and environmentally benign procedure for the construction of various bioactive spirooxindoles has been developed by condensation reactions of isatins, malononitrile and α-methylene carbonyl compounds/enols in the presence of starch solution as expedient, eco-friendly and biodegradable catalyst at 60 °C. The prominent features of the above protocol are short reaction time, high atom economy, simple work-up, cost-effectiveness, avoidance of toxic chemicals.

Keywords

Spirooxindoles Green synthesis Multicomponent synthesis Starch 

Notes

Acknowledgements

P.S. and G.K. are thankful to UGC and, CSIR, New Delhi respectively, for the grant of junior and senior research fellowship.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of ChemistryMaitreyi CollegeChanakyapuri, New DelhiIndia
  2. 2.Department of ChemistryUniversity of DelhiNew DelhiIndia

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