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Recent Advances in Triazolyl Nucleosides

  • Smriti Srivastava
  • Vipin K. Maikhuri
  • Divya Mathur
  • Ashok K. Prasad
Conference paper

Abstract

Nucleosides and its modified analogues are important components and possess key roles in various biological processes. Copper catalyzed 1,3-dipolar cycloadditions have been emerged as an excellent tool to join azide and alkyne moieties to form triazolyl compounds. Presence of triazole group enhances the therapeutic potential as well as fluorescence properties of the modified nucleosides. Owing to the designing and development of the new triazolyl nucleosides for their various biological and photophysical application at faster pace, there is a need to have knowledge of the recent developments in this area. The review herein highlights the various modifications, therapeutic importance and other applications of recently reported triazolyl-nucleosides.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Smriti Srivastava
    • 1
  • Vipin K. Maikhuri
    • 1
  • Divya Mathur
    • 2
  • Ashok K. Prasad
    • 1
  1. 1.Department of ChemistryUniversity of DelhiNew DelhiIndia
  2. 2.Department of ChemistryDaulat Ram College, University of DelhiDelhiIndia

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