Liquid-Based Cytology and Automated Screening Devices in Cytology Sample
The liquid-based cytology (LBC) is an increasingly popular technique in cervical and exfoliative cytology processing. LBC is free of blood, mucus and drying artefact, and it provides clean, monolayered smear in small area of the slide. Presently two widely used techniques of LBC are available in the market: ThinPrep and SurePath. The present chapter discusses the basic principle and technique of these two systems. Relative advantages and disadvantages of LBC and conventional preparations are also discussed. The chapter also elucidates the principle of the two types of automated screening devices (BD FocalPoint GS Imaging System and Hologic’l ThinPrep Imaging System) in cervical cytology. Each system has its own advantages and limitations.
KeywordsLiquid-based cytology Monolayered smear ThinPrep SurePath Automated screening device BD FocalPoint GS Imaging System Hologic l ThinPrep Imaging System
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